Development Level

Tbio 27 | 11,445
Tchem 8 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal testis morphology 2 | 43
decreased vertical activity 2 | 208
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal limb bud morphology 1 | 17
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal vitreous body morphol... 1 | 10
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
increased blood urea nitrogen ... 1 | 48
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58

Disease

Carcinoma 27 | 11,493
lung cancer 17 | 4,740
osteosarcoma 17 | 7,950
ovarian cancer 17 | 8,520
Cancer 15 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
psoriasis 14 | 6,694
glioblastoma 13 | 5,792
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
pancreatic cancer 13 | 2,398
atypical teratoid / rhabdoid tumor 12 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Breast cancer 11 | 3,578
lung adenocarcinoma 11 | 2,716
invasive ductal carcinoma 10 | 2,951
Kidney cancer 9 | 2,613
ependymoma 9 | 4,679
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
pituitary cancer 8 | 1,972
Alzheimer's disease 7 | 658
Liver Cirrhosis, Experimental 7 | 769
Schizophrenia 7 | 1,160
acute quadriplegic myopathy 7 | 1,158
adult high grade glioma 7 | 3,801
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
medulloblastoma, large-cell 7 | 6,241
non-small cell lung cancer 7 | 2,890
Amyotrophic lateral sclerosis 6 | 451
Atherosclerosis 6 | 291
Coronary artery disease 6 | 268
Rheumatoid arthritis 6 | 1,191
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
group 3 medulloblastoma 6 | 4,104
interstitial cystitis 6 | 2,312
oligodendroglioma 6 | 2,850
spina bifida 6 | 1,074
Arthritis 5 | 290
Bipolar Disorder 5 | 666
Depressive disorder 5 | 409
Hypertensive disease 5 | 292
Parkinson's disease 5 | 392
Prostatic Neoplasms 5 | 495
Spontaneous abortion 5 | 113
Vascular disease 5 | 319
aldosterone-producing adenoma 5 | 665
astrocytic glioma 5 | 2,597
group 4 medulloblastoma 5 | 1,855
non-small cell lung carcinoma 5 | 317
pancreatic carcinoma 5 | 562
pediatric high grade glioma 5 | 1,064
Adverse reaction to drug 4 | 61
Asthma 4 | 385
Breast Neoplasms 4 | 445
Cerebrovascular disease 4 | 238
Chemical and Drug Induced Liver Injury 4 | 195
Dementia 4 | 175
Drug-Related Side Effects and Adverse Reactions 4 | 62
Endometriosis 4 | 540
Inflammatory bowel disease 4 | 151
Lung disease 4 | 142
Neoplasm Metastasis 4 | 168
Neurodegenerative disease 4 | 414
Osteoporosis 4 | 363
Pulmonary Fibrosis 4 | 106
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
juvenile dermatomyositis 4 | 1,187
Acquired metabolic disease 3 | 336
Atopic dermatitis 3 | 952
Cholestasis 3 | 155
Heart disease 3 | 306
Hypersensitivity reaction type II disease 3 | 253
Hypertension 3 | 396
Inflammation 3 | 120
Kidney Diseases 3 | 114
Kidney disease 3 | 430
Mood Disorders 3 | 184
Myocardial Ischemia 3 | 169
Myopathy 3 | 185
Neoplasm Invasiveness 3 | 161
Osteoarthritis 3 | 184
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
Proteinuria 3 | 144
Thrombophilia 3 | 38
Type 2 diabetes mellitus 3 | 272
Venous Thrombosis 3 | 47
active Crohn's disease 3 | 922
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
fibroadenoma 3 | 559
hereditary spastic paraplegia 3 | 318
tuberculosis 3 | 2,010

Tissue

Digestive Tract 38 | 17,369
Endocrine System 38 | 18,159
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Blood and immune system 37 | 16,909
Female tissues 37 | 17,400
Respiratory system 37 | 16,393
Nervous System 36 | 16,725
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 8 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

GO Process

positive regulation of protein... 38 | 38
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Syntaxin-binding protein 5-like STXBP5L Tbio Non-IDG -0.71494 6.16 5
Titin TTN Tbio Kinase -3.24415 1743.0 123
Rab effector Noc2 RPH3AL Tbio Non-IDG -1.26757 23.0 148
Fibrinogen alpha chain FGA Tbio Non-IDG -2.88066 753.1 595
Peptidyl-prolyl cis-trans isomerase A PPIA Tclin Enzyme -2.97822 870.7 436
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 Tchem Ion Channel -2.44473 312.3 199
Fibrinogen gamma chain FGG Tbio Non-IDG -2.21041 158.7 384