Development Level

Tbio 26 | 11,445
Tchem 13 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
impaired glucose tolerance 3 | 75
abnormal embryo size 2 | 220
abnormal locomotor behavior 2 | 24
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased pulmonary respirator... 1 | 5
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged stomach 1 | 2
increased IgG2b level 1 | 1
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
small thymus 1 | 16
tremors 1 | 39

Disease

Carcinoma 28 | 11,493
ovarian cancer 26 | 8,520
psoriasis 26 | 6,694
glioblastoma 21 | 5,792
medulloblastoma, large-cell 21 | 6,241
osteosarcoma 21 | 7,950
Cancer 19 | 2,499
atypical teratoid / rhabdoid tumor 15 | 5,112
pancreatic cancer 15 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
lung adenocarcinoma 14 | 2,716
lung cancer 14 | 4,740
Kidney cancer 13 | 2,613
ependymoma 13 | 4,679
group 3 medulloblastoma 13 | 4,104
Breast cancer 12 | 3,578
adult high grade glioma 12 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
non-small cell lung cancer 12 | 2,890
ductal carcinoma in situ 11 | 1,745
lung carcinoma 11 | 2,843
malignant mesothelioma 11 | 3,232
interstitial cystitis 10 | 2,312
invasive ductal carcinoma 10 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
pituitary cancer 10 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
oligodendroglioma 9 | 2,850
Astrocytoma, Pilocytic 8 | 3,081
breast carcinoma 8 | 1,638
primitive neuroectodermal tumor 8 | 3,035
spina bifida 8 | 1,074
subependymal giant cell astrocytoma 8 | 2,287
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
astrocytic glioma 7 | 2,597
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
ulcerative colitis 7 | 1,819
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
Rheumatoid arthritis 6 | 1,191
astrocytoma 6 | 1,146
cutaneous lupus erythematosus 6 | 1,057
dermatomyositis 6 | 966
primary pancreatic ductal adenocarcinoma 6 | 1,109
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Diarrhea 5 | 253
Down syndrome 5 | 499
Endometrial cancer 5 | 311
Melanoma 5 | 711
Skin cancer 5 | 469
adrenocortical carcinoma 5 | 1,428
esophageal adenocarcinoma 5 | 737
nasopharyngeal carcinoma 5 | 1,058
tuberculosis 5 | 2,010
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Arthritis 4 | 290
Asthma 4 | 385
Depressive disorder 4 | 409
Epilepsy 4 | 792
Liver Cirrhosis, Experimental 4 | 769
Mental Depression 4 | 333
Multiple myeloma 4 | 1,332
Obesity 4 | 678
Prostatic Neoplasms 4 | 495
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
fibroadenoma 4 | 559
pancreatic carcinoma 4 | 562
sarcoidosis 4 | 370
Anemia 3 | 365
Disease Models, Animal 3 | 155
Failure to gain weight 3 | 365
Heart disease 3 | 306
Hypersensitivity reaction type II disease 3 | 253
Large auricle 3 | 87
Large dysplastic ears 3 | 87
Large pinnae 3 | 87
Large prominent ears 3 | 87
Large protruding ears 3 | 87
Large, floppy ears 3 | 87
Liver cancer 3 | 604
Liver neoplasms 3 | 130
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Macrotia 3 | 87
Major Depressive Disorder 3 | 301
Myopia 3 | 176
Pediatric failure to thrive 3 | 365
Seizures 3 | 596
Unipolar Depression 3 | 250
Vomiting 3 | 116
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
hepatocellular carcinoma 3 | 547
juvenile dermatomyositis 3 | 1,187

Tissue

Digestive Tract 44 | 17,369
Female tissues 44 | 17,400
Respiratory system 44 | 16,393
Skin and soft tissues 44 | 17,230
Endocrine System 43 | 18,159
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Urinary Tract 43 | 16,678
Blood and immune system 42 | 16,909
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 27 | 12,091
Kinase 11 | 634
Enzyme 5 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

positive regulation of protein... 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anterior gradient protein 2 homolog AGR2 Tbio Non-IDG -2.07496 136.6 594
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Serine/threonine-protein kinase WNK3 WNK3 Tchem Kinase -1.14290 17.3 193
Sorbin and SH3 domain-containing protein 1 SORBS1 Tbio Non-IDG -1.57341 40.2 224
Protein RER1 RER1 Tbio Non-IDG -1.57552 40.0 65
Protein kinase C eta type PRKCH Tchem Kinase -1.79158 65.4 184
Neurexin-1-beta NRXN1 Tbio Non-IDG -1.88807 125.1 174
Villin-1 VIL1 Tbio Non-IDG -2.20137 162.5 349
Rho-related GTP-binding protein RhoG RHOG Tbio Enzyme -2.04297 108.1 142
Kinesin-1 heavy chain KIF5B Tbio Non-IDG -2.32485 196.1 326