Development Level

Tbio 10 | 10,625
Tchem 8 | 1,890
Tclin 3 | 602

IMPC Phenotype

preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 2 | 260
tremors 2 | 34
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal digit morphology 1 | 13
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
cataract 1 | 26
decreased bone mineral content 1 | 157
decreased circulating alkaline... 1 | 41
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased circulating alkaline... 1 | 119
limb grasping 1 | 35

Disease

Cancer 16 | 2,346
ovarian cancer 14 | 8,491
psoriasis 13 | 6,685
diabetes mellitus 9 | 1,663
glioblastoma 9 | 5,572
osteosarcoma 9 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
Alzheimer's disease 7 | 644
lung adenocarcinoma 7 | 2,714
lung cancer 7 | 4,473
malignant mesothelioma 7 | 3,163
medulloblastoma, large-cell 7 | 6,234
Breast cancer 6 | 3,098
non-small cell lung cancer 6 | 2,798
pilocytic astrocytoma 6 | 3,086
Kidney disease 5 | 397
atypical teratoid / rhabdoid tumor 5 | 4,369
group 3 medulloblastoma 5 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
pancreatic cancer 5 | 2,300
Arthritis 4 | 248
Obesity 4 | 616
Osteoporosis 4 | 259
Vascular disease 4 | 281
adrenocortical carcinoma 4 | 1,427
adult high grade glioma 4 | 2,148
astrocytoma 4 | 1,493
invasive ductal carcinoma 4 | 2,950
oligodendroglioma 4 | 2,849
posterior fossa group A ependymoma 4 | 1,511
sonic hedgehog group medulloblastoma 4 | 1,482
ulcerative colitis 4 | 2,087
Adenoma 3 | 165
Brain disease 3 | 84
Carcinoma 3 | 2,147
Cardiomegaly 3 | 66
Diabetic Retinopathy 3 | 53
Endometriosis 3 | 535
Heart disease 3 | 279
Liver carcinoma 3 | 217
Liver disease 3 | 219
Lung Neoplasms 3 | 171
Lung disease 3 | 136
Mammary Neoplasms 3 | 410
Multiple myeloma 3 | 1,327
Polycystic Ovary Syndrome 3 | 334
Prostatic Neoplasms 3 | 471
Waldenstrons macroglobulinemia 3 | 764
cystic fibrosis 3 | 1,670
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pediatric high grade glioma 3 | 2,712
primary pancreatic ductal adenocarcinoma 3 | 1,271
primitive neuroectodermal tumor 3 | 3,031
Anemia 2 | 252
Atherosclerosis 2 | 275
Atopic dermatitis 2 | 944
Bladder Neoplasm 2 | 109
COPD 2 | 116
Carcinoma of colon 2 | 32
Cataract 2 | 104
Cerebrovascular disease 2 | 231
Coronary artery disease 2 | 240
Down syndrome 2 | 548
Glaucoma 2 | 135
Hepatitis C 2 | 90
Hypertension 2 | 293
Hypertensive disease 2 | 193
IGA Glomerulonephritis 2 | 454
Infertility 2 | 163
Ischemic stroke 2 | 12
Lactic acidosis 2 | 43
Metabolic syndrome X 2 | 155
Myopathy 2 | 128
Neoplastic Syndromes, Hereditary 2 | 48
Nerve Degeneration 2 | 73
Neuropathy 2 | 210
Pancreatic Neoplasm 2 | 79
Parkinson Disease 2 | 105
Parkinson's disease 2 | 364
Peripheral vascular disease 2 | 90
Pick disease 2 | 1,893
Seizures 2 | 95
Squamous cell carcinoma 2 | 96
Status Epilepticus 2 | 85
Stomach Neoplasms 2 | 282
Toxic encephalopathy 2 | 131
active ulcerative colitis 2 | 477
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
chronic lymphosyte leukemia 2 | 232
inflammatory breast cancer 2 | 404
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung carcinoma 2 | 413
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 674
tuberculosis and treatment for 3 months 2 | 327

Tissue

Blood and immune system 21 | 17,994
Cardiovascular System 21 | 17,957
Digestive Tract 21 | 18,472
Endocrine System 21 | 18,511
Female tissues 21 | 18,646
Liver and Pancreas 21 | 18,135
Male tissues 21 | 17,968
Nervous System 21 | 18,560
Skin and soft tissues 21 | 18,114
Urinary Tract 21 | 18,443
Respiratory system 20 | 17,483

Target Family

Non-IDG 8 | 11,969
Kinase 7 | 634
Enzyme 4 | 4,146
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

GO Process

positive regulation of protein... 21 | 21
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 2-alpha kinase 3 EIF2AK3 Tchem Kinase -3.01129 806.4 424
G2 and S phase-expressed protein 1 GTSE1 Tbio Enzyme -1.41297 25.7 187
Cyclin-dependent kinase 1 CDK1 Tchem Kinase -3.25783 1710.8 1724
CDK5 regulatory subunit-associated protein 3 CDK5RAP3 Tbio Non-IDG -1.25579 19.7 133
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -3.98540 8801.0 1257
Transforming growth factor beta-2 TGFB2 Tchem Non-IDG -3.13045 1015.3 342
Tumor necrosis factor receptor superfamily member 16 NGFR Tchem Non-IDG -3.04691 1125.0 687
Prothrombin F2 Tclin Enzyme -4.50962 31685.2 484
Insulin INS Tbio Non-IDG -5.16178 141255.4 1549
Sestrin-2 SESN2 Tbio Non-IDG -1.78334 73.0 151