Development Level

Tbio 12 | 11,178
Tchem 6 | 1,885
Tclin 5 | 612

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96

Disease

Carcinoma 15 | 11,192
medulloblastoma, large-cell 12 | 6,086
osteosarcoma 12 | 7,766
ovarian cancer 12 | 8,297
adult high grade glioma 10 | 3,701
atypical teratoid / rhabdoid tumor 10 | 4,971
glioblastoma 10 | 5,635
group 3 medulloblastoma 10 | 4,002
Cancer 9 | 2,388
primitive neuroectodermal tumor 9 | 2,957
astrocytic glioma 8 | 2,530
ependymoma 8 | 4,559
Epilepsy 7 | 775
lung cancer 7 | 4,607
psoriasis 7 | 6,514
Astrocytoma, Pilocytic 6 | 3,006
Schizophrenia 6 | 1,136
ulcerative colitis 6 | 1,765
Hypertension 5 | 372
diabetes mellitus 5 | 1,683
oligodendroglioma 5 | 2,768
Alzheimer's disease 4 | 640
Cerebrovascular disease 4 | 223
Cognitive delay 4 | 596
Global developmental delay 4 | 596
Heart disease 4 | 288
Mental and motor retardation 4 | 596
Neurodegenerative disease 4 | 402
Seizures 4 | 584
Toxic encephalopathy 4 | 139
colon cancer 4 | 1,428
invasive ductal carcinoma 4 | 2,867
lung adenocarcinoma 4 | 2,627
malignant mesothelioma 4 | 3,135
non-small cell lung cancer 4 | 2,799
subependymal giant cell astrocytoma 4 | 2,230
Amyloidosis 3 | 64
Aspergillosis 3 | 25
Autosomal recessive predisposition 3 | 1,407
Bipolar Disorder 3 | 646
Breast cancer 3 | 3,469
Delayed Puberty 3 | 94
Depressive disorder 3 | 401
Dilated ventricles (finding) 3 | 119
Hepatomegaly 3 | 280
Idiopathic scoliosis 3 | 31
Liver Cirrhosis, Experimental 3 | 733
Long QT syndrome 1 3 | 20
Malignant hyperthermia 3 | 26
Multiple epiphyseal dysplasia 3 | 18
Multiple myeloma 3 | 1,296
Open mouth 3 | 44
Osteoporosis 3 | 348
Otitis externa 3 | 10
Parkinsonian Disorders 3 | 55
Pertussis 3 | 20
Pick disease 3 | 1,856
Pseudoachondroplasia 3 | 14
Recurrent respiratory infections 3 | 138
Short stature 3 | 514
Splenomegaly 3 | 186
Sporotrichosis 3 | 9
Stomach Neoplasms 3 | 287
Supraventricular arrhythmia 3 | 4
Tetanus 3 | 67
Ventricular arrhythmia 3 | 27
breast carcinoma 3 | 1,589
interstitial cystitis 3 | 2,237
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,204
lung carcinoma 3 | 2,755
nasopharyngeal carcinoma 3 | 1,024
pancreatic cancer 3 | 2,322
Constipation 2 | 174
Deafness 2 | 193
Delayed bone age 2 | 132
Disease Progression 2 | 133
Failure to gain weight 2 | 359
Hearing Loss, Partial 2 | 180
Highly variable clinical phenotype 2 | 147
Highly variable phenotype and severity 2 | 147
Highly variable phenotype, even within families 2 | 147
Hyperreflexia 2 | 208
Infantile onset 2 | 236
Muscle Spasticity 2 | 192
Neoplasm Invasiveness 2 | 151
Parkinson Disease 2 | 64
Parkinson's disease 2 | 378
Pediatric failure to thrive 2 | 359
Phenotypic variability 2 | 147
Pneumonia 2 | 169
Strabismus 2 | 265
Waldenstrons macroglobulinemia 2 | 742
adrenocortical carcinoma 2 | 1,385
atypical teratoid/rhabdoid tumor 2 | 349
gastric carcinoma 2 | 781
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,872
medulloblastoma 2 | 702
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,911
spina bifida 2 | 1,053

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Enzyme 11 | 4,145
Non-IDG 9 | 12,091
Kinase 2 | 634
GPCR 1 | 408

GO Process

positive regulation of protein... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform PPP2R5A Tchem Enzyme -0.54568 3.09 202
Glucosylceramidase GBA Tchem Enzyme -3.22080 1617.1 299
Leukocyte immunoglobulin-like receptor subfamily B member 2 LILRB2 Tbio Non-IDG -2.03244 85.4 165
Signal peptide peptidase-like 3 SPPL3 Tbio Enzyme -1.36769 23.9 88
Adenosine receptor A1 ADORA1 Tclin GPCR -3.08657 1177.9 342
Nuclear envelope phosphatase-regulatory subunit 1 CNEP1R1 Tbio Enzyme 0.32 0.61 9
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform PPP2R5D Tbio Enzyme -0.70843 3.59 261
Cell division cycle-associated protein 2 CDCA2 Tbio Non-IDG -1.20885 18.7 84
Calmodulin-2 CALM3 Tclin Non-IDG -3.59834 5859.5 0
Calmodulin-3 CALM3 Tclin Non-IDG -3.59140 5859.5 0