Development Level

Tbio 46 | 10,625
Tchem 7 | 1,890
Tclin 3 | 602
Tdark 3 | 7,003

IMPC Term

decreased lean body mass 3 | 195
increased or absent threshold ... 3 | 128
preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
decreased body length 2 | 108
decreased body weight 2 | 174
abnormal bone mineralization 1 | 55
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
absent startle reflex 1 | 15
decreased B cell number 1 | 30
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased granulocyte number 1 | 8
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hyperactivity 1 | 108
hypoactivity 1 | 89
increased T cell number 1 | 15
increased exploration in new e... 1 | 56
increased sacral vertebrae num... 1 | 62
male infertility 1 | 62
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 36 | 8,484
osteosarcoma 33 | 7,933
psoriasis 32 | 6,685
lung cancer 26 | 4,466
glioblastoma 22 | 5,572
medulloblastoma, large-cell 20 | 6,234
Cancer 18 | 2,346
atypical teratoid / rhabdoid tumor 16 | 4,369
Breast cancer 15 | 3,094
malignant mesothelioma 15 | 3,162
primitive neuroectodermal tumor 15 | 3,031
invasive ductal carcinoma 14 | 2,950
ependymoma 13 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
lung adenocarcinoma 13 | 2,713
lung carcinoma 13 | 2,844
non-small cell lung cancer 13 | 2,798
pediatric high grade glioma 13 | 2,712
oligodendroglioma 12 | 2,849
pilocytic astrocytoma 12 | 3,086
breast carcinoma 11 | 1,614
diabetes mellitus 11 | 1,663
ductal carcinoma in situ 11 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
spina bifida 11 | 1,064
astrocytoma 10 | 1,493
pancreatic cancer 10 | 2,300
ulcerative colitis 9 | 2,087
Alzheimer's disease 8 | 644
Pick disease 8 | 1,893
group 4 medulloblastoma 8 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Carcinoma 7 | 2,147
Multiple myeloma 7 | 1,327
adrenocortical carcinoma 7 | 1,427
cystic fibrosis 7 | 1,665
medulloblastoma 7 | 1,524
Intellectual disability 6 | 573
Lung Neoplasms 6 | 171
Prostatic Neoplasms 6 | 471
Rheumatoid Arthritis 6 | 1,160
acute quadriplegic myopathy 6 | 1,157
colon cancer 6 | 1,475
group 3 medulloblastoma 6 | 2,254
interstitial cystitis 6 | 2,299
sonic hedgehog group medulloblastoma 6 | 1,482
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 1,557
Adenoma 5 | 165
Parkinson's disease 5 | 364
active Crohn's disease 5 | 918
acute myeloid leukemia 5 | 780
astrocytic glioma 5 | 2,241
atypical teratoid/rhabdoid tumor 5 | 1,095
fibroadenoma 5 | 557
pituitary cancer 5 | 1,972
tuberculosis and treatment for 6 months 5 | 686
Autistic Disorder 4 | 320
Dementia 4 | 129
Hypertension 4 | 287
Liver carcinoma 4 | 217
Multiple Sclerosis 4 | 498
Muscular atrophy 4 | 67
Neurodegenerative disease 4 | 383
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 765
active ulcerative colitis 4 | 477
adult high grade glioma 4 | 2,148
cutaneous lupus erythematosus 4 | 1,056
dermatomyositis 4 | 933
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 832
Animal Mammary Neoplasms 3 | 136
Atopic dermatitis 3 | 944
Bipolar Disorder 3 | 266
Colorectal Neoplasms 3 | 217
Crohn's disease 3 | 304
Down syndrome 3 | 548
Endometriosis 3 | 535
Hydrolethalus syndrome 3 | 128
Inflammatory Bowel Diseases 3 | 87
Juvenile rheumatoid arthritis 3 | 104
Mammary Neoplasms 3 | 410
Mesothelioma 3 | 40
Myocardial Infarction 3 | 126
Neoplastic Cell Transformation 3 | 81
Osteoarthritis 3 | 96
Pain 3 | 70
Schizophrenia 3 | 501
aldosterone-producing adenoma 3 | 664
hepatocellular carcinoma 3 | 532
ovarian neoplasm 3 | 97
pancreatic carcinoma 3 | 567
posterior fossa group A ependymoma 3 | 1,511
posterior fossa group B ependymoma 3 | 1,530
primary pancreatic ductal adenocarcinoma 3 | 1,271
Myocardial Ischemia 2 | 169
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
nephrosclerosis 2 | 329

Tissue

Blood and immune system 59 | 17,995
Cardiovascular System 59 | 17,958
Digestive Tract 59 | 18,473
Endocrine System 59 | 18,512
Female tissues 59 | 18,647
Liver and Pancreas 59 | 18,136
Male tissues 59 | 17,969
Nervous System 59 | 18,561
Respiratory system 59 | 17,484
Urinary Tract 59 | 18,444
Skin and soft tissues 58 | 18,115

Target Family

Non-IDG 32 | 11,971
Enzyme 18 | 4,146
Kinase 5 | 634
Transcription Factor 4 | 1,400

GO Process

positive regulation of protein... 59 | 59
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.60609 403.7 216
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha PPP2R3A Tbio Enzyme -1.19072 14.4 144
Glycogen synthase kinase-3 alpha GSK3A Tclin Kinase -1.81647 52.3 722
Fizzy-related protein homolog FZR1 Tbio Non-IDG -1.74457 58.7 182
ADP-ribosylation factor-binding protein GGA3 GGA3 Tbio Non-IDG -1.62754 38.5 124
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.43649 30.3 84
Vacuolar protein sorting-associated protein 28 homolog VPS28 Tbio Non-IDG -1.27884 15.2 86
E3 ubiquitin-protein ligase MYLIP MYLIP Tbio Enzyme -2.01928 109.1 122