Development Level

Tbio 3 | 11,445
Tclin 3 | 613
Tchem 2 | 1,598

IMPC Phenotype

abnormal gait 1 | 69
decreased body weight 1 | 161
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
preweaning lethality, complete... 1 | 979

Disease

Cancer 7 | 2,499
Carcinoma 7 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
ovarian cancer 6 | 8,520
glioblastoma 5 | 5,792
malignant mesothelioma 5 | 3,232
Congenital Epicanthus 4 | 177
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
Abnormality of the ulna 3 | 10
Acquired scoliosis 3 | 281
Anteverted nostril 3 | 191
Blepharoptosis 3 | 231
Byzanthine arch palate 3 | 194
Cell Transformation, Neoplastic 3 | 97
Cognitive delay 3 | 608
Colorectal Neoplasms 3 | 243
Cryptorchidism 3 | 296
Curvature of spine 3 | 282
Downward slant of palpebral fissure 3 | 158
Dull intelligence 3 | 645
Global developmental delay 3 | 608
High forehead 3 | 102
Hypoplastic mandible condyle 3 | 275
Intellectual disability 3 | 1,016
Large auricle 3 | 87
Large dysplastic ears 3 | 87
Large pinnae 3 | 87
Large prominent ears 3 | 87
Large protruding ears 3 | 87
Large, floppy ears 3 | 87
Low intelligence 3 | 645
Macrotia 3 | 87
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Micrognathism 3 | 275
Muscle hypotonia 3 | 571
Neoplasm Invasiveness 3 | 161
Neoplastic Cell Transformation 3 | 89
Orbital separation excessive 3 | 244
Poor school performance 3 | 645
Short stature 3 | 531
Tall forehead 3 | 102
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
group 3 medulloblastoma 3 | 4,104
subependymal giant cell astrocytoma 3 | 2,287
Abnormality of vision 2 | 40
Absence of eyebrows 2 | 31
Acute kidney injury 2 | 70
Adenocarcinoma 2 | 122
Adenocarcinoma of lung 2 | 142
Aplasia/Hypoplasia of the eyebrow 2 | 31
Atrial Septal Defects 2 | 85
Big calvaria 2 | 147
Brachydactyly 2 | 156
Breast Neoplasms 2 | 445
Carcinoma, Squamous Cell 2 | 110
Cardiomyopathy 2 | 116
Coarse facial features 2 | 108
Congenital deafness 2 | 185
Deafness 2 | 198
Dry skin 2 | 75
Hearing Loss, Partial 2 | 185
Hemangioma, Cavernous 2 | 20
Hyperhidrosis disorder 2 | 81
Hypertrophic Cardiomyopathy 2 | 117
Ichthyoses 2 | 41
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Increased sweating 2 | 81
Low posterior hairline 2 | 52
Mammary Neoplasms 2 | 425
Neoplasm Metastasis 2 | 168
Osteoporosis 2 | 363
Palmoplantar keratosis 2 | 74
Premature Birth 2 | 77
Premature birth of newborn 2 | 67
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Pulmonary Stenosis 2 | 45
Sparse hair 2 | 59
Sparse or absent eyebrows 2 | 31
Sparse/absent eyebrows 2 | 31
Specific learning disability 2 | 47
Squamous cell carcinoma 2 | 129
Sweating 2 | 81
Thickened facial skin with coarse facial features 2 | 108
Thin, sparse hair 2 | 59
Underdeveloped brows 2 | 38
Underdeveloped supraorbital ridges 2 | 38
Xerosis 2 | 75
hearing impairment 2 | 199
sarcoidosis 2 | 370

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Kinase 3 | 634
Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

positive regulation of product... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ATP-dependent RNA helicase DDX5 DDX5 Tbio Enzyme -2.08566 121.1 344
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
N-myc proto-oncogene protein MYCN Tbio Transcription Factor -3.35747 2111.2 242
Protein lin-28 homolog A LIN28A Tbio Transcription Factor -2.44709 277.0 494
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.83744 60.9 883
Epidermal growth factor receptor EGFR Tclin Kinase -4.02650 10013.1 6418
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222