Development Level

Tbio 11 | 11,445
Tchem 10 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal bone structure 2 | 187
preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal tooth morphology 1 | 24
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Cancer 19 | 2,499
Carcinoma 17 | 11,493
psoriasis 15 | 6,694
osteosarcoma 14 | 7,950
ovarian cancer 14 | 8,520
glioblastoma 13 | 5,792
atypical teratoid / rhabdoid tumor 10 | 5,112
lung cancer 10 | 4,740
malignant mesothelioma 10 | 3,232
diabetes mellitus 9 | 1,728
medulloblastoma, large-cell 9 | 6,241
Astrocytoma, Pilocytic 8 | 3,081
Breast Neoplasms 8 | 445
Breast cancer 8 | 3,578
Hypertensive disease 8 | 292
Kidney disease 8 | 430
Mammary Neoplasms 8 | 425
astrocytoma 8 | 1,146
ependymoma 8 | 4,679
Hypertension 7 | 396
Schizophrenia 7 | 1,160
Vascular disease 7 | 319
adult high grade glioma 7 | 3,801
colon cancer 7 | 1,478
lung carcinoma 7 | 2,843
Carcinoma, Hepatocellular 6 | 228
Cell Transformation, Neoplastic 6 | 97
Liver carcinoma 6 | 240
Prostatic Neoplasms 6 | 495
ductal carcinoma in situ 6 | 1,745
group 3 medulloblastoma 6 | 4,104
group 4 medulloblastoma 6 | 1,855
lung adenocarcinoma 6 | 2,716
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
ulcerative colitis 6 | 1,819
Acquired scoliosis 5 | 281
Adenocarcinoma 5 | 122
Amyotrophic lateral sclerosis 5 | 451
Anemia 5 | 365
Arthritis 5 | 290
Brain Ischemia 5 | 110
Curvature of spine 5 | 282
Depressive disorder 5 | 409
Heart disease 5 | 306
Liver disease 5 | 237
Lung Neoplasms 5 | 232
Neoplastic Cell Transformation 5 | 89
Pancreatic Neoplasm 5 | 85
Pancreatic Neoplasms 5 | 85
Reperfusion Injury 5 | 86
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
Skin Neoplasms 5 | 69
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
non-small cell lung cancer 5 | 2,890
Adenoma 4 | 167
Arthritis, Juvenile 4 | 126
Asthma 4 | 385
Atherosclerosis 4 | 291
Cardiomegaly 4 | 116
Cholestasis, Extrahepatic 4 | 25
Cleft Palate 4 | 271
Cocaine-Related Disorders 4 | 92
Colonic Neoplasms 4 | 142
Coronary artery disease 4 | 268
Endometriosis 4 | 540
Epilepsy 4 | 792
Eye disease 4 | 62
Inflammatory bowel disease 4 | 151
Juvenile arthritis 4 | 126
Liver neoplasms 4 | 130
Lymphoid leukemia 4 | 160
Major Depressive Disorder 4 | 301
Obesity 4 | 678
Osteoporosis 4 | 363
Pneumonia 4 | 174
Pulmonary Fibrosis 4 | 106
Recurrent respiratory infections 4 | 141
Short stature 4 | 531
Stomach Neoplasms 4 | 300
Toxic encephalopathy 4 | 141
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
dermatomyositis 4 | 966
invasive ductal carcinoma 4 | 2,951
non-small cell lung carcinoma 4 | 317
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
Alzheimer's disease 3 | 658
Mental Depression 3 | 333
Polycystic ovary syndrome 3 | 360
chronic lymphosyte leukemia 3 | 204
hepatocellular carcinoma 3 | 547

Tissue

Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Blood and immune system 21 | 16,909
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192
Nervous System 20 | 16,725
Respiratory system 20 | 16,393

Target Family

Transcription Factor 12 | 1,400
Non-IDG 7 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

GO Process

positive regulation of pri-miR... 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Telomerase reverse transcriptase TERT Tchem Enzyme -3.56910 3506.4 643
Bone morphogenetic protein receptor type-1A BMPR1A Tchem Kinase -2.34984 211.0 622
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058
Transcriptional enhancer factor TEF-1 TEAD1 Tbio Transcription Factor -1.71108 45.2 164
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298