Development Level

Tbio 6 | 11,445
Tclin 5 | 613
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal heart shape 1 | 5
abnormal seminal vesicle morph... 1 | 114
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
enlarged heart 1 | 210
increased body weight 1 | 25
increased circulating triglyce... 1 | 42
increased monocyte cell number 1 | 63

Disease

Cancer 9 | 2,499
Carcinoma 9 | 11,493
lung cancer 9 | 4,740
osteosarcoma 8 | 7,950
ovarian cancer 8 | 8,520
Alzheimer's disease 6 | 658
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
Schizophrenia 5 | 1,160
adult high grade glioma 5 | 3,801
diabetes mellitus 5 | 1,728
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
subependymal giant cell astrocytoma 5 | 2,287
Cerebrovascular disease 4 | 238
Epilepsy 4 | 792
Heart disease 4 | 306
Hypertension 4 | 396
Kidney cancer 4 | 2,613
Toxic encephalopathy 4 | 141
atypical teratoid / rhabdoid tumor 4 | 5,112
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
oligodendroglioma 4 | 2,850
psoriasis 4 | 6,694
ulcerative colitis 4 | 1,819
Amyloidosis 3 | 67
Aspergillosis 3 | 26
Bipolar Disorder 3 | 666
Idiopathic scoliosis 3 | 31
Long QT syndrome 1 3 | 20
Malignant hyperthermia 3 | 26
Multiple epiphyseal dysplasia 3 | 18
Multiple myeloma 3 | 1,332
Otitis externa 3 | 10
Pertussis 3 | 20
Pick disease 3 | 1,894
Pseudoachondroplasia 3 | 14
Sporotrichosis 3 | 10
Supraventricular arrhythmia 3 | 4
Tetanus 3 | 68
Ventricular arrhythmia 3 | 27
malignant mesothelioma 3 | 3,232
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
urothelial carcinoma 3 | 318
Acquired metabolic disease 2 | 336
Calcinosis 2 | 70
Crohn's disease 2 | 321
Decreased platelet count 2 | 111
Dizziness 2 | 26
Hepatomegaly 2 | 285
Hypereosinophilic syndrome 2 | 71
Hypertensive disease 2 | 292
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Lymphoid leukemia 2 | 160
MAJOR AFFECTIVE DISORDER 2 2 | 22
Mastocytosis 2 | 27
Melanoma 2 | 711
Myeloproliferative disease 2 | 16
Myocardial Infarction 2 | 151
Polycythemia vera 2 | 27
Prostatic Neoplasms 2 | 495
Rheumatoid arthritis 2 | 1,191
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Thrombocytopenia 2 | 197
Vertigo 2 | 29
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109
Diabetic Cardiomyopathies 1 | 10
Gastrointestinal stromal tumor 1 | 62
Hamman-Rich syndrome 1 | 34
Hematocrit increased 1 | 5
Hemoglobin increased 1 | 6
Increased red blood cell mass 1 | 4
Malignant neoplasm of skin 1 | 15
Pancreatic Neuroendocrine Tumor 1 | 45
Peripheral thrombosis 1 | 3
Skin Neoplasms 1 | 69

Tissue

Cardiovascular System 14 | 15,192
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Nervous System 13 | 16,725

Target Family

Non-IDG 6 | 12,091
Enzyme 4 | 4,145
Kinase 3 | 634
GPCR 1 | 408

GO Process

positive regulation of phospho... 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
Inactive serine/threonine-protein kinase VRK3 VRK3 Tbio Kinase -0.74516 7.30 63
Calmodulin-2 CALM3 Tclin Non-IDG -3.59834 5859.5 0
Calmodulin-3 CALM3 Tclin Non-IDG -3.59140 5859.5 0
CMRF35-like molecule 8 CD300A Tbio Non-IDG -1.58380 41.3 219
Type-2 angiotensin II receptor AGTR2 Tchem GPCR -3.30172 1972.1 147
Calmodulin-1 CALM3 Tclin Non-IDG -3.59093 5859.5 0
A-kinase anchor protein 6 AKAP6 Tbio Enzyme -1.39062 24.2 108
Integrin alpha-1 ITGA1 Tbio Non-IDG -1.97879 88.9 397
Heat shock protein HSP 90-beta HSP90AB1 Tchem Non-IDG -2.04844 173.5 988