Development Level

Tclin 6 | 613
Tchem 3 | 1,598

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
Breast cancer 7 | 3,578
Cancer 7 | 2,499
cystic fibrosis 7 | 1,696
Kidney cancer 6 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung cancer 6 | 4,740
non-small cell lung cancer 6 | 2,890
osteosarcoma 6 | 7,950
psoriasis 6 | 6,694
Gastrointestinal stromal tumor 5 | 62
Renal Cell Carcinoma 5 | 214
Sarcoma of soft tissue 5 | 11
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
tuberculosis 5 | 2,010
Breast Neoplasms 4 | 445
Chronic eosinophilic leukemia 4 | 11
Depressive disorder 4 | 409
Follicular thyroid carcinoma 4 | 14
Hamman-Rich syndrome 4 | 34
Hypereosinophilic syndrome 4 | 71
Idiopathic hypereosinophilic syndrome 4 | 10
Liver Cirrhosis, Experimental 4 | 769
Mammary Neoplasms 4 | 425
Mastocytosis 4 | 27
Pancreatic Neuroendocrine Tumor 4 | 45
Papillary thyroid carcinoma 4 | 43
Schizophrenia 4 | 1,160
astrocytic glioma 4 | 2,597
ductal carcinoma in situ 4 | 1,745
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Blastic phase chronic myeloid leukemia 3 | 58
Carcinoma of thyroid 3 | 17
Chronic Myelocytic Leukemia Accelerated Phase 3 | 59
Chronic phase chronic myeloid leukemia 3 | 45
Cleft Palate 3 | 271
Delayed bone age 3 | 136
Dermatofibrosarcoma protuberans 3 | 15
Disease Progression 3 | 136
Eosinophilia 3 | 28
Generalized osteopenia 3 | 99
Heart disease 3 | 306
Isolated cases 3 | 72
Liver cell carcinoma 3 | 15
Lung Neoplasms 3 | 232
Myelodysplastic/ Myeloproliferative Diseases associated with Platelet-derived Growth Factor Receptor 3 | 9
Myeloproliferative disease 3 | 16
Osteopenia 3 | 99
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 3 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 3 | 47
Seizures 3 | 596
Skin cancer 3 | 469
Systemic mast cell disease 3 | 12
atypical teratoid / rhabdoid tumor 3 | 5,112
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
non-small cell lung carcinoma 3 | 317
Acrocephalosyndactylia 2 | 17
Adenoma 2 | 167
Blepharoptosis 2 | 231
Constipation 2 | 181
Craniofacial Abnormalities 2 | 151
Downward slant of palpebral fissure 2 | 158
Dyschezia 2 | 135
Exophthalmos 2 | 112
Fatigue 2 | 182
Intestinal Obstruction 2 | 31
Keratitis 2 | 62
Liver Cirrhosis 2 | 181
Lung diseases 2 | 50
Melanoma 2 | 711
Mesothelioma 2 | 38
Mood Disorders 2 | 184
Myocardial Infarction 2 | 151
Nausea and vomiting 2 | 97
Neoplasm Metastasis 2 | 168
Osteoporosis 2 | 363
Polycythemia vera 2 | 27
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Pruritus 2 | 58
Sensorineural Hearing Loss (disorder) 2 | 284
Skull malformation 2 | 38
Somatic mutation 2 | 61
Stomach Neoplasms 2 | 300

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Kinase 6 | 634
GPCR 1 | 408
Non-IDG 1 | 12,091
Nuclear Receptor 1 | 48

GO Process

positive regulation of phospho... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Abelson tyrosine-protein kinase 2 ABL2 Tchem Kinase -1.86293 71.2 358
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Platelet-activating factor receptor PTAFR Tchem GPCR -2.02420 116.1 134
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -4.00542 10573.5 798
Platelet-derived growth factor receptor alpha PDGFRA Tclin Kinase -2.95012 809.9 1423
Platelet-derived growth factor receptor beta PDGFRB Tclin Kinase -2.89315 712.3 1390