Development Level

Tbio 36 | 11,445
Tchem 15 | 1,598
Tclin 14 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 2 | 298
decreased T cell number 2 | 15
decreased bone mineral content 2 | 151
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal pericardium morpholog... 1 | 26
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
absent startle reflex 1 | 24
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased CD4-positive, alpha ... 1 | 4
increased IgG2b level 1 | 1
increased circulating alkaline... 1 | 122
increased heart left ventricle... 1 | 4
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
prenatal lethality 1 | 28
tremors 1 | 39

Disease

Carcinoma 51 | 11,493
Cancer 45 | 2,499
ovarian cancer 43 | 8,520
osteosarcoma 41 | 7,950
lung cancer 38 | 4,740
psoriasis 33 | 6,694
glioblastoma 31 | 5,792
invasive ductal carcinoma 28 | 2,951
malignant mesothelioma 27 | 3,232
medulloblastoma, large-cell 27 | 6,241
Breast cancer 26 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
Kidney cancer 24 | 2,613
interstitial cystitis 24 | 2,312
diabetes mellitus 23 | 1,728
non-small cell lung cancer 23 | 2,890
lung adenocarcinoma 22 | 2,716
lung carcinoma 22 | 2,843
ependymoma 21 | 4,679
ulcerative colitis 21 | 1,819
cystic fibrosis 20 | 1,696
Astrocytoma, Pilocytic 19 | 3,081
Liver Cirrhosis, Experimental 19 | 769
adult high grade glioma 19 | 3,801
atypical teratoid / rhabdoid tumor 18 | 5,112
ductal carcinoma in situ 18 | 1,745
oligodendroglioma 18 | 2,850
Atherosclerosis 17 | 291
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
pancreatic cancer 17 | 2,398
Kidney disease 16 | 430
Schizophrenia 16 | 1,160
pituitary cancer 16 | 1,972
Bipolar Disorder 15 | 666
Obesity 15 | 678
breast carcinoma 15 | 1,638
Coronary artery disease 14 | 268
Depressive disorder 14 | 409
astrocytic glioma 14 | 2,597
subependymal giant cell astrocytoma 14 | 2,287
tuberculosis 14 | 2,010
Breast Neoplasms 13 | 445
Heart disease 13 | 306
Hypertension 13 | 396
Mammary Neoplasms 13 | 425
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Alzheimer's disease 12 | 658
Polycystic ovary syndrome 12 | 360
adrenocortical carcinoma 12 | 1,428
group 3 medulloblastoma 12 | 4,104
group 4 medulloblastoma 12 | 1,855
Autosomal recessive predisposition 11 | 1,442
Cerebrovascular disease 11 | 238
Melanoma 11 | 711
Rheumatoid arthritis 11 | 1,191
Anemia 10 | 365
Mental Depression 10 | 333
Skin cancer 10 | 469
astrocytoma 10 | 1,146
gastric carcinoma 10 | 807
primary Sjogren syndrome 10 | 735
primitive neuroectodermal tumor 10 | 3,035
Arthritis 9 | 290
Diabetic retinopathy 9 | 56
Down syndrome 9 | 499
Hypertensive disease 9 | 292
Myocardial Ischemia 9 | 169
colon cancer 9 | 1,478
cutaneous lupus erythematosus 9 | 1,057
Atopic dermatitis 8 | 952
Liver disease 8 | 237
Major Depressive Disorder 8 | 301
Myocardial Infarction 8 | 151
Neoplasm Metastasis 8 | 168
Osteoporosis 8 | 363
Pick disease 8 | 1,894
Prostatic Neoplasms 8 | 495
Pulmonary Fibrosis 8 | 106
Renal Cell Carcinoma 8 | 214
Seizures 8 | 596
Skin Neoplasms 8 | 69
Unipolar Depression 8 | 250
fibroadenoma 8 | 559
primary pancreatic ductal adenocarcinoma 8 | 1,109
Arthritis, Rheumatoid 7 | 174
Asthma 7 | 385
Epilepsy 7 | 792
Fatty Liver 7 | 70
Fibrosis 7 | 44
Thrombocytopenia 7 | 197
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
esophageal adenocarcinoma 7 | 737
mucosa-associated lymphoid tissue lymphoma 7 | 484
non primary Sjogren syndrome sicca 7 | 891
Duchenne muscular dystrophy 6 | 601
Hypereosinophilic syndrome 6 | 71
Lung Neoplasms 6 | 232
pediatric high grade glioma 6 | 1,064
urothelial carcinoma 6 | 318

Tissue

Endocrine System 65 | 18,159
Digestive Tract 64 | 17,369
Female tissues 64 | 17,400
Liver and Pancreas 64 | 16,750
Skin and soft tissues 63 | 17,230
Blood and immune system 62 | 16,909
Nervous System 62 | 16,725
Urinary Tract 62 | 16,678
Male tissues 61 | 17,142
Respiratory system 61 | 16,393
Cardiovascular System 60 | 15,192

Target Family

Non-IDG 34 | 12,091
Kinase 15 | 634
Enzyme 8 | 4,145
GPCR 4 | 408
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

positive regulation of phospha... 65 | 65
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Reelin RELN Tbio Non-IDG -2.78255 645.2 121
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
Phosphoinositide 3-kinase adapter protein 1 PIK3AP1 Tbio Enzyme -0.26163 1.48 198