Development Level

Tclin 11 | 613
Tbio 9 | 11,445
Tchem 9 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal retina morphology 2 | 71
embryonic lethality prior to t... 2 | 278
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
decreased circulating serum al... 1 | 82
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased monocyte cell number 1 | 63
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56

Disease

Cancer 24 | 2,499
Carcinoma 23 | 11,493
osteosarcoma 18 | 7,950
ovarian cancer 18 | 8,520
psoriasis 16 | 6,694
lung cancer 15 | 4,740
Breast cancer 14 | 3,578
Kidney cancer 14 | 2,613
malignant mesothelioma 13 | 3,232
medulloblastoma, large-cell 12 | 6,241
glioblastoma 11 | 5,792
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
non-small cell lung cancer 11 | 2,890
ulcerative colitis 11 | 1,819
lung adenocarcinoma 10 | 2,716
lung carcinoma 10 | 2,843
breast carcinoma 9 | 1,638
cystic fibrosis 9 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
invasive ductal carcinoma 9 | 2,951
Renal Cell Carcinoma 8 | 214
Skin cancer 8 | 469
adult high grade glioma 8 | 3,801
diabetes mellitus 8 | 1,728
ependymoma 8 | 4,679
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
Astrocytoma, Pilocytic 7 | 3,081
astrocytic glioma 7 | 2,597
atypical teratoid / rhabdoid tumor 7 | 5,112
pancreatic cancer 7 | 2,398
Blastic phase chronic myeloid leukemia 6 | 58
Chronic Myelocytic Leukemia Accelerated Phase 6 | 59
Schizophrenia 6 | 1,160
Skin Neoplasms 6 | 69
colon cancer 6 | 1,478
cutaneous lupus erythematosus 6 | 1,057
ductal carcinoma in situ 6 | 1,745
gastric carcinoma 6 | 807
group 4 medulloblastoma 6 | 1,855
subependymal giant cell astrocytoma 6 | 2,287
Bipolar Disorder 5 | 666
Chronic phase chronic myeloid leukemia 5 | 45
Depressive disorder 5 | 409
Gastrointestinal stromal tumor 5 | 62
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
Melanoma 5 | 711
Pancreatic Neuroendocrine Tumor 5 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 5 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 5 | 47
Rheumatoid arthritis 5 | 1,191
Sarcoma of soft tissue 5 | 11
adrenocortical carcinoma 5 | 1,428
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Arthritis 4 | 290
Carcinoma of thyroid 4 | 17
Carcinoma, Hepatocellular 4 | 228
Cleft Palate 4 | 271
Colorectal Neoplasms 4 | 243
Hamman-Rich syndrome 4 | 34
Heart disease 4 | 306
Hypertension 4 | 396
Increased gastric cancer 4 | 21
Liver cancer 4 | 604
Liver carcinoma 4 | 240
Liver cell carcinoma 4 | 15
Multiple, subcutaneous nodules 4 | 53
Pick disease 4 | 1,894
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Stomach Neoplasms 4 | 300
Subcutaneous nodule 4 | 53
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
mucosa-associated lymphoid tissue lymphoma 4 | 484
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
sarcoidosis 4 | 370
Anemia 3 | 365
Atopic dermatitis 3 | 952
Epilepsy 3 | 792
Exophthalmos 3 | 112
Hepatomegaly 3 | 285
Hypereosinophilic syndrome 3 | 71
Hypersensitivity reaction type II disease 3 | 253
Isolated cases 3 | 72
Liver Cirrhosis 3 | 181
Mastocytosis 3 | 27
Neoplasm Invasiveness 3 | 161
Psychotic Disorders 3 | 151
Status Epilepticus 3 | 98
Urticaria 3 | 67
active ulcerative colitis 3 | 764
astrocytoma 3 | 1,146
cystic fibrosis and chronic rhinosinusitis 3 | 214
spina bifida 3 | 1,074

Tissue

Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Liver and Pancreas 30 | 16,750
Nervous System 30 | 16,725
Skin and soft tissues 30 | 17,230
Cardiovascular System 29 | 15,192
Female tissues 29 | 17,400
Male tissues 29 | 17,142
Respiratory system 29 | 16,393
Urinary Tract 29 | 16,678

Target Family

Kinase 16 | 634
Non-IDG 12 | 12,091
Enzyme 1 | 4,145
GPCR 1 | 408

GO Process

positive regulation of phospha... 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Fibroblast growth factor receptor 3 FGFR3 Tclin Kinase -3.00731 1050.1 479
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
Tumor necrosis factor alpha-induced protein 8-like protein 3 TNFAIP8L3 Tdark Non-IDG -0.64300 4.23 66
C-C chemokine receptor type 7 CCR7 Tbio GPCR -2.99480 983.1 687
Receptor-type tyrosine-protein kinase FLT3 FLT3 Tclin Kinase -3.31736 2112.7 1076
Tyrosine-protein kinase Fgr FGR Tchem Kinase -2.37977 226.9 400