Development Level

Tbio 22 | 11,651
Tchem 3 | 1,388
Tclin 3 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased or absent threshold ... 2 | 101
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal ovary morphology 1 | 7
absent epididymis 1 | 3
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

osteosarcoma 19 | 7,950
Carcinoma 18 | 11,493
glioblastoma 18 | 5,792
psoriasis 18 | 6,694
ovarian cancer 15 | 8,520
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
medulloblastoma, large-cell 13 | 6,241
adult high grade glioma 12 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
Astrocytoma, Pilocytic 11 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
invasive ductal carcinoma 11 | 2,951
lung cancer 11 | 4,740
lung carcinoma 11 | 2,843
non-small cell lung cancer 11 | 2,890
Breast cancer 10 | 3,578
Cancer 10 | 2,499
group 3 medulloblastoma 10 | 4,104
interstitial cystitis 10 | 2,312
pancreatic cancer 10 | 2,398
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
malignant mesothelioma 9 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
atypical teratoid / rhabdoid tumor 8 | 5,112
Autosomal recessive predisposition 7 | 1,442
ependymoma 7 | 4,679
subependymal giant cell astrocytoma 7 | 2,287
Bipolar Disorder 6 | 666
Liver Cirrhosis, Experimental 6 | 769
Obesity 6 | 678
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
Fever 5 | 138
Rheumatoid arthritis 5 | 1,191
diabetes mellitus 5 | 1,728
lung adenocarcinoma 5 | 2,716
mucosa-associated lymphoid tissue lymphoma 5 | 484
periodontitis 5 | 293
Atherosclerosis 4 | 291
Coronary artery disease 4 | 268
Dull intelligence 4 | 645
Glaucoma 4 | 239
Hyperinsulinism 4 | 133
Hypertensive disease 4 | 292
Intellectual disability 4 | 1,016
Kidney disease 4 | 430
Liver disease 4 | 237
Low intelligence 4 | 645
Lung Neoplasms 4 | 232
Major Depressive Disorder 4 | 301
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Pneumonia 4 | 174
Poor school performance 4 | 645
Splenomegaly 4 | 190
Unipolar Depression 4 | 250
dermatomyositis 4 | 966
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 735
primitive neuroectodermal tumor 4 | 3,035
Abnormality of retinal pigmentation 3 | 111
Allergic hypersensitivity disease 3 | 126
Alzheimer Disease 3 | 83
Alzheimer's disease 3 | 658
Anemia 3 | 365
Anteverted nostril 3 | 191
Atopic dermatitis 3 | 952
Blind Vision 3 | 111
Blindness, Legal 3 | 110
Broad flat nasal bridge 3 | 236
Conductive hearing loss 3 | 123
Dementia 3 | 175
Gout 3 | 104
Hypertension 3 | 396
Influenza 3 | 142
Leishmaniasis 3 | 47
Liver Cirrhosis 3 | 181
Malaria 3 | 160
Myocardial Ischemia 3 | 169
Myopathy 3 | 185
Nasal bridge wide 3 | 236
Neoplasm Invasiveness 3 | 161
Neuropathy 3 | 261
Ophthalmoplegia 3 | 106
Pick disease 3 | 1,894
Premature Birth 3 | 77
Retinal pigment epithelial abnormality 3 | 111
Seizures 3 | 596
Sensorineural Hearing Loss (disorder) 3 | 284
Stomach Neoplasms 3 | 300
Vasculitis 3 | 80
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
oligodendroglioma 3 | 2,850
posterior fossa group A ependymoma 3 | 468
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Liver and Pancreas 28 | 16,750
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Urinary Tract 26 | 16,678
Respiratory system 25 | 16,393
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 3 | 4,145
Transcription Factor 3 | 1,400
Kinase 2 | 634
Transporter 2 | 473

GO Process

positive regulation of phagocy... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B Tbio Non-IDG -2.61667 619.4 476
Calreticulin CALR Tbio Non-IDG -3.19563 1544.2 778
Apoptosis-associated speck-like protein containing a CARD PYCARD Tbio Non-IDG -1.86744 55.9 477
Alpha-2-HS-glycoprotein AHSG Tbio Non-IDG -3.09085 1300.3 437
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.58058 376.0 164
Ras-related protein Rab-27A RAB27A Tbio Enzyme -2.30319 204.9 308
Dynamin-2 DNM2 Tchem Non-IDG -2.43547 282.5 143
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
Mannose-binding protein C MBL2 Tbio Non-IDG -2.78880 522.8 359
Vesicular integral-membrane protein VIP36 LMAN2 Tbio Non-IDG -1.40373 27.5 117