Development Level

Tbio 42 | 10,625
Tchem 24 | 1,890
Tclin 15 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal behavior 4 | 226
decreased kidney weight 3 | 7
thrombocytopenia 3 | 46
abnormal femur morphology 2 | 14
corneal opacity 2 | 25
decreased blood urea nitrogen ... 2 | 31
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
impaired pupillary reflex 2 | 14
increased circulating HDL chol... 2 | 63
increased circulating alkaline... 2 | 119
increased mean corpuscular hem... 2 | 93
preweaning lethality, complete... 2 | 633
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal cornea morphology 1 | 24
abnormal eyelid morphology 1 | 6
abnormal fibula morphology 1 | 2
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal mandible morphology 1 | 2
abnormal maxilla morphology 1 | 16
abnormal pelvic girdle bone mo... 1 | 11
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vocalization 1 | 21
abnormal zygomatic bone morpho... 1 | 3
absent startle reflex 1 | 15
absent teeth 1 | 4
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased coping response 1 | 5
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged adrenal glands 1 | 3
enlarged heart 1 | 111
enlarged kidney 1 | 7
enlarged spleen 1 | 26
enlarged uterus 1 | 3
female infertility 1 | 34
hydrometra 1 | 13
impaired righting response 1 | 19
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating LDL chol... 1 | 15
increased circulating aspartat... 1 | 17
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
lethargy 1 | 5
male infertility 1 | 62
mydriasis 1 | 9
narrow eye opening 1 | 15
polycystic kidney 1 | 9
short tibia 1 | 82
small thymus 1 | 11

Disease

Cancer 49 | 2,346
psoriasis 42 | 6,685
osteosarcoma 41 | 7,933
ovarian cancer 40 | 8,484
glioblastoma 38 | 5,572
lung cancer 34 | 4,466
invasive ductal carcinoma 33 | 2,950
lung carcinoma 33 | 2,844
pilocytic astrocytoma 30 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
malignant mesothelioma 28 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,988
medulloblastoma, large-cell 26 | 6,234
diabetes mellitus 25 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
Breast cancer 23 | 3,094
subependymal giant cell astrocytoma 23 | 2,287
atypical teratoid / rhabdoid tumor 22 | 4,369
pediatric high grade glioma 22 | 2,712
ulcerative colitis 22 | 2,087
Obesity 19 | 616
interstitial cystitis 19 | 2,299
oligodendroglioma 19 | 2,849
cystic fibrosis 18 | 1,665
lung adenocarcinoma 18 | 2,713
Carcinoma 17 | 2,147
Rheumatoid Arthritis 17 | 1,160
group 4 medulloblastoma 17 | 1,875
non-small cell lung cancer 17 | 2,798
pancreatic cancer 17 | 2,300
tuberculosis 17 | 1,557
Alzheimer's disease 16 | 644
Kidney disease 16 | 396
colon cancer 16 | 1,475
ependymoma 15 | 2,514
pituitary cancer 15 | 1,972
posterior fossa group A ependymoma 15 | 1,511
Arthritis 14 | 248
astrocytoma 14 | 1,493
juvenile dermatomyositis 14 | 1,189
Anemia 13 | 252
Atherosclerosis 13 | 275
Coronary artery disease 13 | 240
Down syndrome 13 | 548
Prostatic Neoplasms 13 | 471
Autistic Disorder 12 | 320
Liver disease 12 | 219
Mammary Neoplasms 12 | 410
Schizophrenia 12 | 501
adrenocortical carcinoma 12 | 1,427
breast carcinoma 12 | 1,614
cutaneous lupus erythematosus 12 | 1,056
Asthma 11 | 349
Cerebrovascular disease 11 | 231
Inflammatory bowel disease 11 | 142
Liver Cirrhosis, Experimental 11 | 108
Myocardial Ischemia 11 | 169
ductal carcinoma in situ 11 | 1,745
primary pancreatic ductal adenocarcinoma 11 | 1,271
primitive neuroectodermal tumor 11 | 3,031
Heart disease 10 | 279
Hypertensive disease 10 | 193
Inflammation 10 | 109
Peripheral Neuropathy 10 | 303
Pick disease 10 | 1,893
Thrombocytopenia 10 | 105
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
primary Sjogren syndrome 10 | 789
Allergic hypersensitivity disease 9 | 123
Duchenne muscular dystrophy 9 | 602
Hypersensitivity reaction type II disease 9 | 235
Hypertension 9 | 287
IGA Glomerulonephritis 9 | 454
Lung disease 9 | 132
Neoplasm Metastasis 9 | 138
Polycystic Ovary Syndrome 9 | 332
Spontaneous abortion 9 | 108
acute quadriplegic myopathy 9 | 1,157
adult high grade glioma 9 | 2,148
Adenoma 8 | 165
Allergic rhinitis 8 | 91
Diabetic Retinopathy 8 | 53
Endometriosis 8 | 535
Hyperglycemia 8 | 120
Myocardial Infarction 8 | 126
Pulmonary Fibrosis 8 | 66
Reperfusion Injury 8 | 84
astrocytic glioma 8 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
group 3 medulloblastoma 8 | 2,254
Acute kidney injury 7 | 65
Atopic dermatitis 7 | 944
Liver carcinoma 7 | 217
Metabolic syndrome X 7 | 155
Multiple Sclerosis 7 | 498
Neuropathy 7 | 210
Osteoporosis 7 | 257
gastric carcinoma 7 | 832
non-small cell lung carcinoma 7 | 413
pancreatic carcinoma 7 | 567

Tissue

Digestive Tract 81 | 18,473
Endocrine System 81 | 18,512
Nervous System 81 | 18,561
Urinary Tract 81 | 18,444
Female tissues 80 | 18,647
Liver and Pancreas 80 | 18,136
Skin and soft tissues 80 | 18,115
Blood and immune system 79 | 17,995
Cardiovascular System 79 | 17,958
Male tissues 79 | 17,969
Respiratory system 78 | 17,484

Target Family

Non-IDG 59 | 11,971
Kinase 14 | 634
Transcription Factor 4 | 1,400
Enzyme 3 | 4,146
GPCR 1 | 406

GO Process

positive regulation of peptidy... 81 | 81
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
Erythroid transcription factor GATA1 Tbio Transcription Factor -2.97791 941.1 675
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
High affinity immunoglobulin epsilon receptor subunit alpha FCER1A Tchem Non-IDG -2.31101 208.2 301
CD81 antigen CD81 Tchem Non-IDG -2.72554 534.7 551
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.47805 3222.2 1533
Low-density lipoprotein receptor-related protein 4 LRP4 Tbio Non-IDG -1.98324 105.2 178
Hepatocyte growth factor HGF Tchem Enzyme -3.28069 2317.3 573
Receptor-interacting serine/threonine-protein kinase 2 RIPK2 Tchem Kinase -1.97280 103.9 435