Development Level

Tbio 52 | 11,651
Tchem 17 | 1,388
Tclin 15 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 3 | 298
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
preweaning lethality, incomple... 3 | 499
thrombocytopenia 3 | 56
abnormal femur morphology 2 | 14
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased lean body mass 2 | 135
impaired pupillary reflex 2 | 26
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal cornea morphology 1 | 31
abnormal eyelid morphology 1 | 7
abnormal fibula morphology 1 | 2
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal mandible morphology 1 | 2
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
abnormal zygomatic bone morpho... 1 | 3
absent startle reflex 1 | 24
absent teeth 1 | 3
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged adrenal glands 1 | 3
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
fused cornea and lens 1 | 5
hydrometra 1 | 53
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
irregularly shaped pupil 1 | 7
male infertility 1 | 123
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small thymus 1 | 16

Disease

Carcinoma 52 | 11,493
Cancer 51 | 2,499
psoriasis 42 | 6,694
osteosarcoma 40 | 7,950
ovarian cancer 40 | 8,520
glioblastoma 38 | 5,792
lung cancer 37 | 4,740
lung carcinoma 34 | 2,843
malignant mesothelioma 33 | 3,232
invasive ductal carcinoma 31 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
Astrocytoma, Pilocytic 28 | 3,081
Breast cancer 27 | 3,578
atypical teratoid / rhabdoid tumor 27 | 5,112
ependymoma 27 | 4,679
diabetes mellitus 26 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
medulloblastoma, large-cell 26 | 6,241
adult high grade glioma 25 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
ulcerative colitis 23 | 1,819
interstitial cystitis 22 | 2,312
subependymal giant cell astrocytoma 22 | 2,287
Schizophrenia 20 | 1,160
cystic fibrosis 20 | 1,696
Kidney cancer 19 | 2,613
group 3 medulloblastoma 19 | 4,104
lung adenocarcinoma 19 | 2,716
non-small cell lung cancer 19 | 2,890
oligodendroglioma 19 | 2,850
tuberculosis 19 | 2,010
Alzheimer's disease 18 | 658
Obesity 18 | 678
Rheumatoid arthritis 18 | 1,191
Anemia 17 | 365
Liver Cirrhosis, Experimental 17 | 769
colon cancer 17 | 1,478
pancreatic cancer 17 | 2,398
pituitary cancer 17 | 1,972
Kidney disease 16 | 430
Autosomal recessive predisposition 15 | 1,442
Depressive disorder 15 | 409
juvenile dermatomyositis 15 | 1,187
Arthritis 14 | 290
breast carcinoma 14 | 1,638
cutaneous lupus erythematosus 14 | 1,057
Atherosclerosis 13 | 291
Breast Neoplasms 13 | 445
Coronary artery disease 13 | 268
Hypertension 13 | 396
Mammary Neoplasms 13 | 425
Prostatic Neoplasms 13 | 495
Thrombocytopenia 13 | 197
group 4 medulloblastoma 13 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Autistic Disorder 12 | 364
Bipolar Disorder 12 | 666
Down syndrome 12 | 499
Hypertensive disease 12 | 292
Liver disease 12 | 237
Myocardial Ischemia 12 | 169
astrocytic glioma 12 | 2,597
Asthma 11 | 385
Cerebrovascular disease 11 | 238
Heart disease 11 | 306
Inflammation 11 | 120
Mental Depression 11 | 333
Pulmonary Fibrosis 11 | 106
adrenocortical carcinoma 11 | 1,428
primitive neuroectodermal tumor 11 | 3,035
Endometriosis 10 | 540
Hyperglycemia 10 | 137
Hypersensitivity reaction type II disease 10 | 253
Inflammatory bowel disease 10 | 151
Lung disease 10 | 142
Myocardial Infarction 10 | 151
Neoplasm Metastasis 10 | 168
Pick disease 10 | 1,894
astrocytoma 10 | 1,146
ductal carcinoma in situ 10 | 1,745
Abortion, Spontaneous 9 | 109
Duchenne muscular dystrophy 9 | 601
Polycystic ovary syndrome 9 | 360
Reperfusion Injury 9 | 86
Spontaneous abortion 9 | 113
acute quadriplegic myopathy 9 | 1,158
Acute kidney injury 8 | 70
Arthritis, Rheumatoid 8 | 174
Carcinoma, Squamous Cell 8 | 110
Liver Cirrhosis 8 | 181
Major Depressive Disorder 8 | 301
Melanoma 8 | 711
Squamous cell carcinoma 8 | 129
Stomach Neoplasms 8 | 300
Unipolar Depression 8 | 250
Vascular disease 8 | 319
gastric carcinoma 8 | 807
non primary Sjogren syndrome sicca 8 | 891
non-small cell lung carcinoma 8 | 317
primary Sjogren syndrome 8 | 735

Tissue

Digestive Tract 83 | 17,369
Endocrine System 83 | 18,159
Female tissues 83 | 17,400
Blood and immune system 82 | 16,909
Respiratory system 82 | 16,393
Liver and Pancreas 81 | 16,750
Male tissues 81 | 17,142
Nervous System 81 | 16,725
Skin and soft tissues 81 | 17,230
Urinary Tract 81 | 16,678
Cardiovascular System 75 | 15,192

Target Family

Non-IDG 63 | 12,091
Kinase 14 | 634
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145
GPCR 1 | 408

GO Process

positive regulation of peptidy... 84 | 84
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075