Development Level

Tbio 38 | 11,445
Tchem 10 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to t... 3 | 278
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal gait 1 | 69
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased B cell number 1 | 5
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
edema 1 | 59
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating potassiu... 1 | 29
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
microphthalmia 1 | 26
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 31 | 11,493
ovarian cancer 25 | 8,520
osteosarcoma 22 | 7,950
Cancer 21 | 2,499
psoriasis 20 | 6,694
glioblastoma 18 | 5,792
lung cancer 18 | 4,740
atypical teratoid / rhabdoid tumor 16 | 5,112
ependymoma 15 | 4,679
Breast cancer 14 | 3,578
malignant mesothelioma 14 | 3,232
adult high grade glioma 13 | 3,801
Astrocytoma, Pilocytic 12 | 3,081
invasive ductal carcinoma 12 | 2,951
lung adenocarcinoma 12 | 2,716
lung carcinoma 11 | 2,843
medulloblastoma, large-cell 11 | 6,241
Kidney cancer 9 | 2,613
Osteoarthritis 9 | 184
diabetes mellitus 9 | 1,728
ductal carcinoma in situ 9 | 1,745
interstitial cystitis 9 | 2,312
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
Hereditary hemorrhagic telangiectasia 8 | 13
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
cystic fibrosis 8 | 1,696
group 3 medulloblastoma 8 | 4,104
ulcerative colitis 8 | 1,819
Anemia 7 | 365
Cleft Palate 7 | 271
Hypertensive disease 7 | 292
group 4 medulloblastoma 7 | 1,855
Acquired scoliosis 6 | 281
Curvature of spine 6 | 282
Increase in blood pressure 6 | 119
Liver Cirrhosis, Experimental 6 | 769
Telangiectasis 6 | 36
astrocytoma 6 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
subependymal giant cell astrocytoma 6 | 2,287
Ankylosis 5 | 28
Autosomal recessive predisposition 5 | 1,442
Brachydactyly 5 | 156
Breast Neoplasms 5 | 445
Cholecystitis 5 | 18
Congenital heart disease 5 | 93
Coronary artery disease 5 | 268
Decreased joint mobility 5 | 53
Hypertension 5 | 396
Liver Cirrhosis 5 | 181
Mammary Neoplasms 5 | 425
Orbital separation excessive 5 | 244
Osteoporosis 5 | 363
Polycystic ovary syndrome 5 | 360
Rheumatoid arthritis 5 | 1,191
Short stature 5 | 531
active ulcerative colitis 5 | 764
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
nasopharyngeal carcinoma 5 | 1,058
oligodendroglioma 5 | 2,850
primary pancreatic ductal adenocarcinoma 5 | 1,109
Atopic dermatitis 4 | 952
Bilateral fifth finger clinodactyly 4 | 110
Cardiomegaly 4 | 116
Colorectal Neoplasms 4 | 243
Congenital deafness 4 | 185
Curvature of little finger 4 | 110
Deafness 4 | 198
Degenerative polyarthritis 4 | 115
Epistaxis 4 | 43
Exophthalmos 4 | 112
Hearing Loss, Partial 4 | 185
Heart disease 4 | 306
Hemangioma, Cavernous 4 | 20
Hemoglobin low 4 | 124
Hypertension, Portal 4 | 22
Hypotrophic malar bone 4 | 129
Iron-Refractory Iron Deficiency Anemia 4 | 15
Liver carcinoma 4 | 240
Malar flattening 4 | 129
Migraine Disorders 4 | 76
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Right atrial isomerism 4 | 29
Visceral heterotaxy 4 | 14
active Crohn's disease 4 | 922
cutaneous lupus erythematosus 4 | 1,057
hearing impairment 4 | 199
juvenile dermatomyositis 4 | 1,187
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010

Tissue

Endocrine System 48 | 18,159
Female tissues 47 | 17,400
Liver and Pancreas 46 | 16,750
Digestive Tract 45 | 17,369
Male tissues 44 | 17,142
Nervous System 44 | 16,725
Skin and soft tissues 44 | 17,230
Urinary Tract 44 | 16,678
Blood and immune system 42 | 16,909
Cardiovascular System 42 | 15,192
Respiratory system 42 | 16,393

Target Family

Non-IDG 38 | 12,091
Kinase 9 | 634
Transcription Factor 1 | 1,400

GO Process

positive regulation of pathway... 48 | 48
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Embryonic growth/differentiation factor 1 GDF1 Tbio Non-IDG -2.00590 102.6 64
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Bone morphogenetic protein 3 BMP3 Tbio Non-IDG -2.11354 130.5 361
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Growth/differentiation factor 6 GDF6 Tbio Non-IDG -2.31035 205.4 110