Development Level

Tbio 40 | 11,445
Tchem 13 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
decreased vertical activity 3 | 208
increased startle reflex 3 | 112
preweaning lethality, complete... 3 | 979
abnormal bone mineralization 2 | 38
abnormal seminal vesicle morph... 2 | 114
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
increased bone mineral density 2 | 72
increased lean body mass 2 | 172
mammalian phenotype 2 | 17
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal craniofacial morpholo... 1 | 33
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased mature B cell number 1 | 7
embryonic lethality prior to t... 1 | 278
hydroencephaly 1 | 14
hydrometra 1 | 53
hyperactivity 1 | 148
increased body length 1 | 32
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
kinked tail 1 | 2
long tibia 1 | 25
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 41 | 11,493
ovarian cancer 40 | 8,520
Cancer 33 | 2,499
osteosarcoma 33 | 7,950
glioblastoma 32 | 5,792
psoriasis 32 | 6,694
ependymoma 28 | 4,679
lung cancer 28 | 4,740
medulloblastoma, large-cell 25 | 6,241
Astrocytoma, Pilocytic 24 | 3,081
atypical teratoid / rhabdoid tumor 24 | 5,112
Breast cancer 22 | 3,578
group 3 medulloblastoma 22 | 4,104
invasive ductal carcinoma 21 | 2,951
malignant mesothelioma 20 | 3,232
non-small cell lung cancer 20 | 2,890
pancreatic cancer 20 | 2,398
adult high grade glioma 19 | 3,801
interstitial cystitis 19 | 2,312
ulcerative colitis 18 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
lung carcinoma 17 | 2,843
cystic fibrosis 16 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
oligodendroglioma 16 | 2,850
pituitary cancer 16 | 1,972
breast carcinoma 15 | 1,638
lung adenocarcinoma 15 | 2,716
subependymal giant cell astrocytoma 15 | 2,287
Osteoporosis 14 | 363
group 4 medulloblastoma 14 | 1,855
primary pancreatic ductal adenocarcinoma 14 | 1,109
astrocytic glioma 13 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
ductal carcinoma in situ 13 | 1,745
Kidney cancer 12 | 2,613
acute quadriplegic myopathy 12 | 1,158
astrocytoma 12 | 1,146
juvenile dermatomyositis 12 | 1,187
Breast Neoplasms 11 | 445
Kidney disease 11 | 430
Mammary Neoplasms 11 | 425
Obesity 11 | 678
Rheumatoid arthritis 11 | 1,191
tuberculosis 11 | 2,010
colon cancer 10 | 1,478
cutaneous lupus erythematosus 10 | 1,057
pediatric high grade glioma 10 | 1,064
Duchenne muscular dystrophy 9 | 601
Liver carcinoma 9 | 240
Multiple myeloma 9 | 1,332
Pick disease 9 | 1,894
Short stature 9 | 531
active Crohn's disease 9 | 922
diabetes mellitus 9 | 1,728
gastric carcinoma 9 | 807
Carcinoma, Hepatocellular 8 | 228
Liver Cirrhosis, Experimental 8 | 769
Osteoarthritis 8 | 184
adrenocortical carcinoma 8 | 1,428
non primary Sjogren syndrome sicca 8 | 891
primitive neuroectodermal tumor 8 | 3,035
Arthritis, Rheumatoid 7 | 174
Atopic dermatitis 7 | 952
Colorectal Neoplasms 7 | 243
Concave bridge of nose 7 | 195
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Fibrodysplasia ossificans progressiva 7 | 17
Liver cancer 7 | 604
Orbital separation excessive 7 | 244
Prostatic Neoplasms 7 | 495
Stomach Neoplasms 7 | 300
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Adenoma 6 | 167
Autosomal recessive predisposition 6 | 1,442
Brachydactyly 6 | 156
Craniofacial Abnormalities 6 | 151
Endometriosis 6 | 540
Hypertension 6 | 396
Hypoplastic mandible condyle 6 | 275
Lung Neoplasms 6 | 232
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Neoplasm Invasiveness 6 | 161
Neoplasm Metastasis 6 | 168
Polycystic ovary syndrome 6 | 360
Pulmonary Fibrosis 6 | 106
Schizophrenia 6 | 1,160
Ventricular Septal Defects 6 | 119
dermatomyositis 6 | 966
nasopharyngeal carcinoma 6 | 1,058
Bilateral fifth finger clinodactyly 5 | 110
Epilepsy 5 | 792
Myocardial Ischemia 5 | 169
Seizures 5 | 596
esophageal adenocarcinoma 5 | 737
mucosa-associated lymphoid tissue lymphoma 5 | 484
periodontitis 5 | 293

Tissue

Endocrine System 55 | 18,159
Female tissues 55 | 17,400
Blood and immune system 54 | 16,909
Digestive Tract 54 | 17,369
Nervous System 54 | 16,725
Respiratory system 54 | 16,393
Skin and soft tissues 54 | 17,230
Liver and Pancreas 53 | 16,750
Male tissues 53 | 17,142
Urinary Tract 53 | 16,678
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 28 | 12,091
Transcription Factor 14 | 1,400
Kinase 9 | 634
Enzyme 5 | 4,145
Ion Channel 1 | 344

GO Process

positive regulation of osteobl... 57 | 57
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Glycerophosphoinositol inositolphosphodiesterase GDPD2 GDPD2 Tbio Enzyme -0.91821 8.09 101
Runt-related transcription factor 2 RUNX2 Tbio Transcription Factor -3.40091 2392.3 631
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
DNA-binding protein inhibitor ID-4 ID4 Tbio Transcription Factor -2.22096 177.3 245
Protein Wnt-7b WNT7B Tbio Non-IDG -1.76807 52.2 46
Discoidin domain-containing receptor 2 DDR2 Tchem Kinase -2.12297 152.1 302
Collagen triple helix repeat-containing protein 1 CTHRC1 Tbio Non-IDG -1.72221 62.3 202