Development Level

Tbio 7 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal pericardium morpholog... 1 | 26
increased heart rate variabili... 1 | 7

Disease

Carcinoma 7 | 11,493
glioblastoma 6 | 5,792
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
Cancer 4 | 2,499
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
Astrocytoma, Pilocytic 3 | 3,081
Intellectual disability 3 | 1,016
atypical teratoid / rhabdoid tumor 3 | 5,112
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Acute Promyelocytic Leukemia 2 | 40
Anemia 2 | 365
Arthritis 2 | 290
Cardiovascular Abnormalities 2 | 31
Depressive disorder 2 | 409
Dull intelligence 2 | 645
Epilepsy 2 | 792
Gynecomastia 2 | 64
Hypersensitivity reaction type II disease 2 | 253
Infantile onset 2 | 238
Infertility, Female 2 | 28
Inflammatory bowel disease 2 | 151
Kidney cancer 2 | 2,613
Leukemia, Promyelocytic, Acute 2 | 36
Low intelligence 2 | 645
Lymphopenia 2 | 67
Meningioma 2 | 41
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Orbital separation excessive 2 | 244
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Poor school performance 2 | 645
Severe combined immunodeficiency 2 | 51
Skin Neoplasms 2 | 69
Skin cancer 2 | 469
Splenomegaly 2 | 190
Syndactyly of fingers 2 | 48
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
pituitary cancer 2 | 1,972
Absence of B cells 1 | 4
Absent B cells 1 | 4
Absent peripheral blood T cells 1 | 4
Acrodermatitis chronica atrophicans 1 | 4
Atypical lymphocyte observed 1 | 10
Basal cell carcinoma of skin 1 | 2
Chronic diarrhea 1 | 29
Combined Cellular And Humoral Immune Defects With Granulomas 1 | 2
Combined immunodeficiency 1 | 5
Combined immunodeficiency with skin granulomas 1 | 2
Compression of spinal cord 1 | 10
Cowden disease 1 | 18
Curry-Jones syndrome 1 | 1
Desquamation of skin soon after birth 1 | 10
Diffusely thickened skin 1 | 20
Exfoliative dermatitis 1 | 24
Facial asymmetry 1 | 32
Failure to thrive secondary to recurrent infections 1 | 4
Fibrous skin tumor of tuberous sclerosis 1 | 18
Fissured tongue 1 | 25
Frequent opportunistic infections 1 | 5
Gastrointestinal hamartomatous polyps 1 | 10
Hamartoma Syndrome, Multiple 1 | 10
Hamartomatous polyp 1 | 10
Hyperkeratosis, generalized 1 | 14
Hypoproteinemia 1 | 8
Low B cell count 1 | 8
Macule 1 | 19
Marfanoid body habitus 1 | 11
Maxillary Neoplasms 1 | 1
Metaplasia 1 | 5
Mucosal telangiectasiae 1 | 14
Multiple, subcutaneous nodules 1 | 53
Omenn syndrome 1 | 13
Pachyderma 1 | 20
Polyp of large intestine 1 | 8
Recurrent fungal infections 1 | 13
Recurrent viral infections 1 | 15
Reticuloendotheliosis, familial, with eosinophilia 1 | 3
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, NK Cell-Positive 1 | 2
Severe T lymphocytopenia 1 | 4
Small thymus 1 | 13
Spinal canal stenosis 1 | 12
Stricture of anus 1 | 13
Subcutaneous lipomas 1 | 9
Subcutaneous nodule 1 | 53
T-Lymphocytopenia 1 | 9
Thyroid Gland Follicular Adenoma 1 | 9
Winter Shortland Temple syndrome 1 | 1

Tissue

Blood and immune system 11 | 16,909
Endocrine System 11 | 18,159
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Urinary Tract 11 | 16,678
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 4 | 12,091
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

positive regulation of organ g... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565
Interleukin-7 IL7 Tbio Non-IDG -3.06671 1222.2 599
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Homeobox protein ARX ARX Tbio Transcription Factor -2.21255 163.7 328
Fibroblast growth factor 8 FGF8 Tbio Non-IDG -2.73368 532.0 299
Y-box-binding protein 3 YBX3 Tbio Transcription Factor -2.13168 143.1 204
V(D)J recombination-activating protein 2 RAG2 Tbio Epigenetic -2.94111 784.2 194
H2.0-like homeobox protein HLX Tbio Transcription Factor -1.82547 73.2 189
Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 Tclin Ion Channel -1.59683 37.4 101
Stress-associated endoplasmic reticulum protein 1 SERP1 Tbio Non-IDG -1.37994 31.0 79