Development Level

Tbio 62 | 11,445
Tchem 10 | 1,598
Tclin 5 | 613
Tdark 4 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
decreased fasted circulating g... 2 | 65
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal ovary morphology 1 | 7
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
absent epididymis 1 | 3
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
premature death 1 | 5
tremors 1 | 39

Disease

Carcinoma 58 | 11,493
atypical teratoid / rhabdoid tumor 43 | 5,112
psoriasis 43 | 6,694
ependymoma 42 | 4,679
glioblastoma 42 | 5,792
medulloblastoma, large-cell 40 | 6,241
ovarian cancer 40 | 8,520
osteosarcoma 35 | 7,950
Cancer 34 | 2,499
primitive neuroectodermal tumor 29 | 3,035
oligodendroglioma 28 | 2,850
lung cancer 27 | 4,740
group 3 medulloblastoma 25 | 4,104
Breast cancer 24 | 3,578
malignant mesothelioma 24 | 3,232
adult high grade glioma 23 | 3,801
astrocytic glioma 23 | 2,597
lung carcinoma 22 | 2,843
Kidney cancer 20 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
Astrocytoma, Pilocytic 19 | 3,081
lung adenocarcinoma 19 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
invasive ductal carcinoma 18 | 2,951
non-small cell lung cancer 18 | 2,890
Intellectual disability 16 | 1,016
ductal carcinoma in situ 16 | 1,745
pancreatic cancer 16 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
pituitary cancer 15 | 1,972
subependymal giant cell astrocytoma 15 | 2,287
breast carcinoma 14 | 1,638
Breast Neoplasms 13 | 445
Mammary Neoplasms 13 | 425
colon cancer 13 | 1,478
medulloblastoma 12 | 720
Epilepsy 11 | 792
Short stature 11 | 531
cystic fibrosis 11 | 1,696
group 4 medulloblastoma 11 | 1,855
tuberculosis 11 | 2,010
Cognitive delay 10 | 608
Dull intelligence 10 | 645
Global developmental delay 10 | 608
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental and motor retardation 10 | 608
Mental deficiency 10 | 645
Muscle hypotonia 10 | 571
Parkinson's disease 10 | 392
Poor school performance 10 | 645
Seizures 10 | 596
gastric carcinoma 10 | 807
interstitial cystitis 10 | 2,312
pediatric high grade glioma 10 | 1,064
ulcerative colitis 10 | 1,819
Pick disease 9 | 1,894
Rheumatoid arthritis 9 | 1,191
Schizophrenia 9 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
acute quadriplegic myopathy 8 | 1,158
adrenocortical carcinoma 8 | 1,428
aldosterone-producing adenoma 8 | 665
diabetes mellitus 8 | 1,728
primary pancreatic ductal adenocarcinoma 8 | 1,109
Bipolar Disorder 7 | 666
Concave bridge of nose 7 | 195
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Down syndrome 7 | 499
Downward slant of palpebral fissure 7 | 158
Endometriosis 7 | 540
Failure to gain weight 7 | 365
Holoprosencephaly 7 | 56
Melanoma 7 | 711
Pediatric failure to thrive 7 | 365
Skin cancer 7 | 469
Strabismus 7 | 270
cutaneous lupus erythematosus 7 | 1,057
dermatomyositis 7 | 966
nasopharyngeal carcinoma 7 | 1,058
Alzheimer's disease 6 | 658
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
Cryptorchidism 6 | 296
Liver Cirrhosis, Experimental 6 | 769
Low set ears 6 | 181
Neoplasm Invasiveness 6 | 161
Obesity 6 | 678
Orbital separation excessive 6 | 244
Prostatic Neoplasms 6 | 495
Short nose 6 | 132
Small head 6 | 374
Small nose 6 | 132
fibroadenoma 6 | 559
juvenile dermatomyositis 6 | 1,187
Asthma 5 | 385
Duchenne muscular dystrophy 5 | 601
Immune system cancer 5 | 140
spina bifida 5 | 1,074

Tissue

Digestive Tract 76 | 17,369
Nervous System 76 | 16,725
Endocrine System 75 | 18,159
Skin and soft tissues 73 | 17,230
Female tissues 71 | 17,400
Blood and immune system 70 | 16,909
Liver and Pancreas 70 | 16,750
Male tissues 69 | 17,142
Urinary Tract 69 | 16,678
Respiratory system 67 | 16,393
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 34 | 12,091
Transcription Factor 29 | 1,400
Enzyme 7 | 4,145
Epigenetic 4 | 242
GPCR 3 | 408
Nuclear Receptor 2 | 48
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

positive regulation of neuron ... 81 | 81
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroblastoma suppressor of tumorigenicity 1 NBL1 Tbio Non-IDG -2.58132 362.9 217
Copine-1 CPNE1 Tbio Non-IDG -1.04880 11.6 151
Nucleosome assembly protein 1-like 2 NAP1L2 Tbio Non-IDG -1.99057 94.6 108
RING finger protein 112 RNF112 Tbio Non-IDG -2.36685 229.7 118
Lysine-specific demethylase 4A KDM4A Tchem Epigenetic -3.06159 1089.8 271
Growth/differentiation factor 6 GDF6 Tbio Non-IDG -2.31035 205.4 110
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
Zinc finger E-box-binding homeobox 1 ZEB1 Tbio Transcription Factor -2.88752 659.2 460
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785