Development Level

Tbio 18 | 11,445
Tchem 7 | 1,598
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
increased circulating LDL chol... 2 | 13
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retinal inner nuclear... 1 | 8
abnormal tooth morphology 1 | 24
absent seminal vesicle 1 | 4
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
male infertility 1 | 123
polycystic kidney 1 | 15
premature death 1 | 5
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small uterus 1 | 3

Disease

Cancer 24 | 2,499
ovarian cancer 23 | 8,520
Carcinoma 21 | 11,493
psoriasis 21 | 6,694
lung cancer 18 | 4,740
glioblastoma 17 | 5,792
medulloblastoma, large-cell 15 | 6,241
osteosarcoma 15 | 7,950
astrocytoma 14 | 1,146
Alzheimer's disease 13 | 658
Breast cancer 13 | 3,578
Schizophrenia 12 | 1,160
atypical teratoid / rhabdoid tumor 12 | 5,112
Down syndrome 11 | 499
ependymoma 11 | 4,679
group 3 medulloblastoma 11 | 4,104
lung carcinoma 11 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
malignant mesothelioma 10 | 3,232
oligodendroglioma 10 | 2,850
Parkinson's disease 9 | 392
Rheumatoid arthritis 9 | 1,191
Toxic encephalopathy 9 | 141
adult high grade glioma 9 | 3,801
diabetes mellitus 9 | 1,728
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
pancreatic cancer 9 | 2,398
Bipolar Disorder 8 | 666
Kidney cancer 8 | 2,613
Pick disease 8 | 1,894
non-small cell lung cancer 8 | 2,890
ulcerative colitis 8 | 1,819
Alzheimer Disease 7 | 83
Astrocytoma, Pilocytic 7 | 3,081
Dementia 7 | 175
Neurodegenerative disease 7 | 414
adrenocortical carcinoma 7 | 1,428
colon cancer 7 | 1,478
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
juvenile dermatomyositis 7 | 1,187
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
Breast Neoplasms 6 | 445
Cerebrovascular disease 6 | 238
Depressive disorder 6 | 409
Intellectual disability 6 | 1,016
Vascular disease 6 | 319
breast carcinoma 6 | 1,638
Arthritis 5 | 290
Cognition Disorders 5 | 32
Hypertension 5 | 396
Kidney disease 5 | 430
Lung Neoplasms 5 | 232
Major Depressive Disorder 5 | 301
Mammary Neoplasms 5 | 425
Nerve Degeneration 5 | 121
Parkinsonian Disorders 5 | 56
Prostatic Neoplasms 5 | 495
Splenomegaly 5 | 190
astrocytic glioma 5 | 2,597
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
non primary Sjogren syndrome sicca 5 | 891
Adenocarcinoma 4 | 122
Alcoholic Intoxication, Chronic 4 | 289
Amyotrophic lateral sclerosis 4 | 451
Asthma 4 | 385
Atherosclerosis 4 | 291
Brain Ischemia 4 | 110
Brain disease 4 | 96
Disease Models, Animal 4 | 155
Hypertensive disease 4 | 292
Melanoma 4 | 711
Mental Depression 4 | 333
Multiple myeloma 4 | 1,332
Obesity 4 | 678
Parkinson Disease 4 | 64
Reperfusion Injury 4 | 86
Seizures 4 | 596
Thrombocytopenia 4 | 197
esophageal adenocarcinoma 4 | 737
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
hepatocellular carcinoma 4 | 547
nephrosclerosis 4 | 333
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
Duchenne muscular dystrophy 3 | 601
Juvenile arthritis 3 | 126
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
gastric carcinoma 3 | 807
mucosa-associated lymphoid tissue lymphoma 3 | 484
spina bifida 3 | 1,074

Tissue

Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Cardiovascular System 29 | 15,192

Target Family

Non-IDG 17 | 12,091
Kinase 5 | 634
Enzyme 4 | 4,145
Transcription Factor 4 | 1,400

GO Process

positive regulation of neuron ... 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.85307 72.5 189
DNA damage-inducible transcript 4 protein DDIT4 Tbio Non-IDG -2.11497 150.3 231
Zinc finger protein 746 ZNF746 Tbio Transcription Factor -0.53123 3.94 34
Integrin alpha-M ITGAM Tbio Non-IDG -3.63427 3939.5 2165
ETS domain-containing protein Elk-1 ELK1 Tbio Transcription Factor -0.51976 3.02 941
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 AIMP2 Tbio Enzyme -1.35413 26.1 138
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045
Proto-oncogene c-Fos FOS Tbio Transcription Factor -4.14231 13598.8 1058
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.92862 84.7 130