Development Level

Tchem 22 | 1,598
Tbio 21 | 11,445
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased vertical activity 4 | 208
embryonic lethality prior to t... 4 | 278
decreased total body fat amoun... 3 | 207
embryonic lethality prior to o... 3 | 239
increased circulating alkaline... 3 | 122
abnormal retina morphology 2 | 71
abnormal sleep behavior 2 | 70
decreased body weight 2 | 161
decreased lean body mass 2 | 135
decreased spleen weight 2 | 10
hypoactivity 2 | 132
increased mean corpuscular hem... 2 | 96
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal social-conspecific in... 1 | 3
abnormal startle reflex 1 | 15
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
enlarged heart 1 | 210
enlarged kidney 1 | 14
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
shortened ST segment 1 | 10
thrombocytopenia 1 | 56

Disease

Cancer 29 | 2,499
medulloblastoma, large-cell 29 | 6,241
Carcinoma 28 | 11,493
lung cancer 28 | 4,740
ovarian cancer 27 | 8,520
osteosarcoma 23 | 7,950
glioblastoma 21 | 5,792
psoriasis 21 | 6,694
atypical teratoid / rhabdoid tumor 18 | 5,112
Schizophrenia 17 | 1,160
malignant mesothelioma 16 | 3,232
oligodendroglioma 16 | 2,850
astrocytic glioma 15 | 2,597
ependymoma 15 | 4,679
Breast cancer 14 | 3,578
adult high grade glioma 14 | 3,801
Astrocytoma, Pilocytic 13 | 3,081
diabetes mellitus 13 | 1,728
group 3 medulloblastoma 13 | 4,104
subependymal giant cell astrocytoma 12 | 2,287
Vascular disease 11 | 319
group 4 medulloblastoma 11 | 1,855
pancreatic cancer 11 | 2,398
tuberculosis 11 | 2,010
Alzheimer's disease 10 | 658
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
invasive ductal carcinoma 10 | 2,951
lung carcinoma 10 | 2,843
Intellectual disability 9 | 1,016
Kidney cancer 9 | 2,613
Obesity 9 | 678
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Epilepsy 8 | 792
Prostatic Neoplasms 8 | 495
Toxic encephalopathy 8 | 141
hepatocellular carcinoma 8 | 547
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
non-small cell lung cancer 8 | 2,890
primitive neuroectodermal tumor 8 | 3,035
Brain Ischemia 7 | 110
Dull intelligence 7 | 645
Kidney disease 7 | 430
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Multiple myeloma 7 | 1,332
Poor school performance 7 | 645
lung adenocarcinoma 7 | 2,716
Diabetes Mellitus, Experimental 6 | 108
Lung disease 6 | 142
Melanoma 6 | 711
Parkinson's disease 6 | 392
Seizures 6 | 596
Small head 6 | 374
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
colon cancer 6 | 1,478
cutaneous lupus erythematosus 6 | 1,057
pituitary cancer 6 | 1,972
Amyotrophic lateral sclerosis 5 | 451
Autosomal recessive predisposition 5 | 1,442
Bipolar Disorder 5 | 666
Brain disease 5 | 96
Carcinoma, Hepatocellular 5 | 228
Cognitive delay 5 | 608
Concave bridge of nose 5 | 195
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Eye disease 5 | 62
Global developmental delay 5 | 608
Liver cancer 5 | 604
Liver carcinoma 5 | 240
Mental and motor retardation 5 | 608
Mesothelioma, Malignant 5 | 105
Multiple Sclerosis 5 | 540
Myocardial Infarction 5 | 151
Polycystic ovary syndrome 5 | 360
Rheumatoid arthritis 5 | 1,191
Skin cancer 5 | 469
Strabismus 5 | 270
atypical teratoid/rhabdoid tumor 5 | 357
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
non primary Sjogren syndrome sicca 5 | 891
non-small cell lung carcinoma 5 | 317
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
ulcerative colitis 5 | 1,819
Arthritis 4 | 290
Contact Dermatitis 4 | 81
Dermatitis, Contact 4 | 71
Endometriosis 4 | 540
Pick disease 4 | 1,894
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
gastric cancer 4 | 459
gastric carcinoma 4 | 807
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074

Tissue

Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Male tissues 46 | 17,142
Skin and soft tissues 46 | 17,230
Blood and immune system 45 | 16,909
Female tissues 45 | 17,400
Nervous System 45 | 16,725
Respiratory system 45 | 16,393
Urinary Tract 45 | 16,678
Cardiovascular System 44 | 15,192
Liver and Pancreas 44 | 16,750

Target Family

Non-IDG 15 | 12,091
Transcription Factor 12 | 1,400
Enzyme 10 | 4,145
Kinase 8 | 634
Ion Channel 2 | 344
Epigenetic 1 | 242

GO Process

positive regulation of neuron ... 48 | 48
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Caspase-2 CASP2 Tchem Enzyme -2.62373 431.8 571
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.44791 277.6 405
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
NAD(P)H dehydrogenase [quinone] 1 NQO1 Tchem Enzyme -3.12097 1326.4 550
DNA damage-inducible transcript 3 protein DDIT3 Tchem Transcription Factor -2.94434 736.0 704
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998