Development Level

Tbio 13 | 11,445
Tchem 5 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
increased total body fat amoun... 3 | 134
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
increased startle reflex 2 | 112
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased heart rate variabili... 1 | 7
limb grasping 1 | 41
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 19 | 11,493
ependymoma 12 | 4,679
Breast cancer 11 | 3,578
osteosarcoma 11 | 7,950
psoriasis 11 | 6,694
Intellectual disability 9 | 1,016
glioblastoma 9 | 5,792
lung cancer 9 | 4,740
Cancer 8 | 2,499
atypical teratoid / rhabdoid tumor 8 | 5,112
ovarian cancer 8 | 8,520
Astrocytoma, Pilocytic 7 | 3,081
Kidney cancer 7 | 2,613
Schizophrenia 7 | 1,160
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
medulloblastoma, large-cell 7 | 6,241
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Microcephaly 6 | 166
Poor school performance 6 | 645
breast carcinoma 6 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
Melanoma 5 | 711
Mood Disorders 5 | 184
Seizures 5 | 596
Small head 5 | 374
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
Abnormally small eyeball 4 | 97
Alzheimer's disease 4 | 658
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Cognitive delay 4 | 608
Decreased size of eyeball 4 | 97
Epilepsy 4 | 792
Global developmental delay 4 | 608
Hypertension 4 | 396
Major Depressive Disorder 4 | 301
Mammary Neoplasms 4 | 425
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Microphthalmia 4 | 76
Microphthalmos 4 | 100
Muscle hypotonia 4 | 571
Strabismus 4 | 270
Syndactyly of fingers 4 | 48
adult high grade glioma 4 | 3,801
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
non-small cell lung cancer 4 | 2,890
tuberculosis 4 | 2,010
Adenoma 3 | 167
Amyotrophic lateral sclerosis 3 | 451
Cataract 3 | 297
Cerebrovascular disease 3 | 238
Colonic Neoplasms 3 | 142
Congenital ocular coloboma (disorder) 3 | 40
Craniofacial Abnormalities 3 | 151
Depressive disorder 3 | 409
Highly variable severity 3 | 157
Holoprosencephaly 3 | 56
Keratitis 3 | 62
Liver Cirrhosis 3 | 181
Liver cancer 3 | 604
Lymphoid leukemia 3 | 160
Movement Disorders 3 | 55
Neoplasm Invasiveness 3 | 161
Neuropathy 3 | 261
Nevoid basal cell carcinoma syndrome 3 | 16
Obesity 3 | 678
Prostatic Neoplasms 3 | 495
Short stature 3 | 531
Skin cancer 3 | 469
Stomach Neoplasms 3 | 300
Syndactyly of the toes 3 | 45
Unipolar Depression 3 | 250
Uterine Cervical Neoplasm 3 | 25
Uterine Cervical Neoplasms 3 | 26
Variable expressivity 3 | 157
Vascular disease 3 | 319
astrocytoma 3 | 1,146
chronic lymphosyte leukemia 3 | 204
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035

Tissue

Endocrine System 20 | 18,159
Nervous System 19 | 16,725
Digestive Tract 18 | 17,369
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Blood and immune system 16 | 16,909
Urinary Tract 16 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 8 | 1,400
GPCR 4 | 408
Enzyme 1 | 4,145

GO Process

positive regulation of neurobl... 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein orthopedia OTP Tbio Transcription Factor -2.26130 187.7 110
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Doublesex- and mab-3-related transcription factor A2 DMRTA2 Tbio Transcription Factor -1.06699 14.5 78
Abnormal spindle-like microcephaly-associated protein ASPM Tbio Non-IDG -1.52453 32.7 40
Vascular endothelial growth factor C VEGFC Tbio Non-IDG -2.99495 1028.1 667
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Forkhead box protein G1 FOXG1 Tbio Transcription Factor -2.63715 438.9 214
Zinc finger protein 335 ZNF335 Tbio Transcription Factor -1.17336 14.8 83
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 SMARCD3 Tbio Non-IDG -1.30404 22.1 170