Development Level

Tbio 20 | 11,651
Tclin 7 | 612
Tchem 3 | 1,388
Tdark 2 | 6,593

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
decreased body length 3 | 101
decreased lean body mass 3 | 135
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lumbar vertebrae num... 1 | 2
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating sodium l... 1 | 71
increased heart rate variabili... 1 | 7
thrombocytopenia 1 | 56

Disease

Carcinoma 26 | 11,493
psoriasis 16 | 6,694
osteosarcoma 14 | 7,950
ovarian cancer 14 | 8,520
Obesity 12 | 678
medulloblastoma, large-cell 12 | 6,241
Autosomal recessive predisposition 10 | 1,442
Short stature 10 | 531
diabetes mellitus 10 | 1,728
glioblastoma 10 | 5,792
group 3 medulloblastoma 9 | 4,104
lung carcinoma 9 | 2,843
Cancer 8 | 2,499
Depressive disorder 8 | 409
Dull intelligence 8 | 645
Intellectual disability 8 | 1,016
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
ependymoma 8 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung cancer 8 | 4,740
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
malignant mesothelioma 7 | 3,232
pancreatic cancer 7 | 2,398
Bipolar Disorder 6 | 666
Congenital hypoplasia of penis 6 | 176
Delayed bone age 6 | 136
Hypoglycemia 6 | 152
Hypothyroidism 6 | 122
Schizophrenia 6 | 1,160
ductal carcinoma in situ 6 | 1,745
oligodendroglioma 6 | 2,850
pituitary cancer 6 | 1,972
Alcoholic Intoxication, Chronic 5 | 289
Astrocytoma, Pilocytic 5 | 3,081
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Hypertensive disease 5 | 292
Hypogonadism 5 | 173
Hypopituitarism 5 | 40
Mental Depression 5 | 333
Mental and motor retardation 5 | 608
Nystagmus 5 | 317
Strabismus 5 | 270
adult high grade glioma 5 | 3,801
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Acromegaly 4 | 51
Adenoma 4 | 167
Alcohol dependence 4 | 107
Anorexia nervosa 4 | 80
Attention deficit hyperactivity disorder 4 | 278
Cocaine-Related Disorders 4 | 92
Congenital hypoplasia of ovary 4 | 30
Cryptorchidism 4 | 296
Gastroesophageal reflux disease 4 | 110
Hypertension 4 | 396
Hypoplastic ovary 4 | 30
Liver Cirrhosis, Experimental 4 | 769
Melanoma 4 | 711
Multicystic Dysplastic Kidney 4 | 52
Pituitary dwarfism 4 | 6
Polycystic ovary syndrome 4 | 360
Prader-Willi syndrome 4 | 48
Retinal Degeneration 4 | 106
Seizures 4 | 596
Small testicle 4 | 75
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
obsessive-compulsive disorder 4 | 61
pancreatic carcinoma 4 | 562
primitive neuroectodermal tumor 4 | 3,035
Alzheimer's disease 3 | 658
Anteverted nostril 3 | 191
Becker muscular dystrophy 3 | 191
Concave bridge of nose 3 | 195
Delayed speech and language development 3 | 112
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Epilepsy 3 | 792
Language Delay 3 | 112
Major Depressive Disorder 3 | 301
Parkinson's disease 3 | 392
Pick disease 3 | 1,894
Pituitary adenoma 3 | 38
Prostatic Neoplasms 3 | 495
Speech Delay 3 | 112
Speech impairment 3 | 112
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
breast carcinoma 3 | 1,638
juvenile dermatomyositis 3 | 1,187
pediatric high grade glioma 3 | 1,064
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 32 | 18,159
Digestive Tract 28 | 17,369
Female tissues 28 | 17,400
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Liver and Pancreas 27 | 16,750
Blood and immune system 26 | 16,909
Skin and soft tissues 26 | 17,230
Male tissues 25 | 17,142
Urinary Tract 25 | 16,678
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 15 | 12,091
Transcription Factor 6 | 1,400
GPCR 5 | 408
Enzyme 3 | 4,145
Transporter 2 | 473
Epigenetic 1 | 242

GO Process

positive regulation of multice... 32 | 32
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ezrin EZR Tbio Non-IDG -2.99865 981.3 1088
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.27852 217.0 1246
D(2) dopamine receptor DRD2 Tclin GPCR -3.28700 1882.2 264
Forkhead box protein S1 FOXS1 Tdark Transcription Factor -0.43453 3.53 53
Nipped-B-like protein NIPBL Tbio Non-IDG -2.25874 186.3 134
Probable G-protein coupled receptor 21 GPR21 Tdark GPCR -0.57204 4.04 59
Peptidyl-prolyl cis-trans isomerase B PPIB Tchem Enzyme -2.24866 187.1 304
Somatotropin GH1 Tbio Non-IDG -3.03406 1736.7 722
Somatoliberin GHRH Tbio Non-IDG -3.26565 1918.4 202
Signal transducer and activator of transcription 5B STAT5B Tchem Transcription Factor -3.02570 950.5 620