Development Level

Tbio 15 | 11,445
Tchem 15 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased lean body mass 2 | 135
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
fused cornea and lens 1 | 5
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 24 | 8,520
Cancer 21 | 2,499
Carcinoma 19 | 11,493
osteosarcoma 19 | 7,950
medulloblastoma, large-cell 15 | 6,241
psoriasis 15 | 6,694
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 13 | 5,792
group 3 medulloblastoma 12 | 4,104
lung cancer 12 | 4,740
invasive ductal carcinoma 10 | 2,951
ependymoma 9 | 4,679
lung adenocarcinoma 9 | 2,716
malignant mesothelioma 9 | 3,232
primitive neuroectodermal tumor 9 | 3,035
adrenocortical carcinoma 8 | 1,428
adult high grade glioma 8 | 3,801
astrocytic glioma 8 | 2,597
colon cancer 8 | 1,478
lung carcinoma 8 | 2,843
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
Pick disease 6 | 1,894
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
dermatomyositis 6 | 966
juvenile dermatomyositis 6 | 1,187
ulcerative colitis 6 | 1,819
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Intellectual disability 5 | 1,016
Mental and motor retardation 5 | 608
Multiple myeloma 5 | 1,332
Prostatic Neoplasms 5 | 495
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer's disease 4 | 658
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Down syndrome 4 | 499
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Schizophrenia 4 | 1,160
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
progressive supranuclear palsy 4 | 676
Adenocarcinoma 3 | 122
Amyotrophic lateral sclerosis 3 | 451
Bipolar Disorder 3 | 666
Carcinoma, Non-Small-Cell Lung 3 | 107
Cleft Palate 3 | 271
Downward slant of palpebral fissure 3 | 158
Epilepsy 3 | 792
Kidney cancer 3 | 2,613
Leukemia 3 | 104
Orbital separation excessive 3 | 244
Polycystic ovary syndrome 3 | 360
Precancerous Conditions 3 | 80
Prostate cancer 3 | 175
Seizures 3 | 596
Short stature 3 | 531
Small head 3 | 374
active Crohn's disease 3 | 922
aldosterone-producing adenoma 3 | 665
cystic fibrosis 3 | 1,696
hereditary spastic paraplegia 3 | 318
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung carcinoma 3 | 317
pituitary cancer 3 | 1,972
Acquired scoliosis 2 | 281
Anemia 2 | 365
Congenital Epicanthus 2 | 177
Curvature of spine 2 | 282
Depressive disorder 2 | 409
Endometriosis 2 | 540
Male infertility 2 | 206
Mental Depression 2 | 333
Pancreatic Neoplasm 2 | 85
acute quadriplegic myopathy 2 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
esophageal adenocarcinoma 2 | 737
limb girdle muscular dystrophy 2A 2 | 213
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 9 | 12,091
Transcription Factor 7 | 1,400
Kinase 5 | 634

GO Process

positive regulation of mitotic... 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Polymerase delta-interacting protein 2 POLDIP2 Tbio Enzyme 0.00000 154
Dynein light chain Tctex-type 3 DYNLT3 Tbio Non-IDG -0.83800 6.25 70
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
Ubiquitin carboxyl-terminal hydrolase 22 USP22 Tbio Enzyme -1.68483 57.9 220
Tubulin--tyrosine ligase TTL Tchem Enzyme -1.33229 15.7 84
Asparagine synthetase [glutamine-hydrolyzing] ASNS Tchem Enzyme -2.40144 244.3 223
Hepatocyte nuclear factor 3-alpha FOXA1 Tbio Transcription Factor -2.41829 249.1 744
SH2 domain-containing adapter protein B SHB Tbio Non-IDG -2.19060 169.7 209
Ribosomal protein S6 kinase beta-1 RPS6KB1 Tchem Kinase -3.18361 0.00000 1818