Development Level

Tbio 2 | 11,651

Disease

Cancer 2 | 2,499
Carcinoma 2 | 11,493
Kidney disease 2 | 430
Nephrogenic adenoma 2 | 10
Nephrogenic adenoma of urinary bladder 2 | 2
Abdomen distended 1 | 43
Arnold-Chiari Malformation, Type I 1 | 5
Athyreosis 1 | 4
Athyroidal hypothyroidism 1 | 5
Atresia of vagina 1 | 10
Bicornuate uterus 1 | 11
Bilateral renal hypoplasia 1 | 1
Bradycardia 1 | 36
Cervix endometriosis 1 | 3
Chorioretinal atrophy 1 | 11
Chronic kidney disease stage 5 1 | 31
Coarse facial features 1 | 108
Coloboma 1 | 51
Coloboma of optic disc 1 | 9
Colorectal Neoplasms 1 | 243
Congenital clubfoot 1 | 109
Congenital hypoplasia of kidney 1 | 32
Congenital hypothyroidism 1 | 26
Constipation 1 | 181
Denys-Drash syndrome 1 | 12
Dry skin 1 | 75
Dyschezia 1 | 135
Ectopic thyroid tissue (disorder) 1 | 2
Endosalpingiosis 1 | 1
FOCAL SEGMENTAL GLOMERULOSCLEROSIS 7 1 | 1
Fatigue 1 | 182
Female Urogenital Diseases 1 | 18
Follicular adenoma 1 | 7
Fundus coloboma 1 | 18
Glomerulosclerosis, Focal Segmental 1 | 28
Goiter 1 | 38
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
HYPOTHYROIDISM, CONGENITAL, DUE TO THYROID DYSGENESIS 1 | 4
Hereditary renal agenesis 1 | 4
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Highly variable severity 1 | 157
Hoarse cry 1 | 5
Hypersomnia 1 | 8
Hypothermia, natural 1 | 17
Icterus 1 | 82
Increased bilirubin level (finding) 1 | 18
Infantile onset 1 | 238
Joint laxity 1 | 54
Kidney Failure, Chronic 1 | 46
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large posterior fontanelle 1 | 3
Large, late-closing fontanelle 1 | 46
Lethargy 1 | 77
Low Vision 1 | 174
Macroglossia 1 | 65
Metanephric adenoma 1 | 9
Microphthalmia 1 | 76
Muscle Weakness 1 | 170
Myopia 1 | 176
Nephrotic Syndrome 1 | 78
Optic nerve dysplasia 1 | 6
Orbital cyst 1 | 8
Oxyphilic adenoma 1 | 22
Papillary thyroid carcinoma 1 | 43
Papillorenal syndrome 1 | 1
Phenotypic variability 1 | 150
Poor growth 1 | 114
Potter's facies 1 | 10
Prenatal onset 1 | 139
Primary physiologic amenorrhea 1 | 55
Proteinuria 1 | 144
RENAL ADYSPLASIA 1 | 25
Raised TSH level 1 | 8
Renal coloboma syndrome 1 | 4
Renal dysplasia 1 | 28
Retrognathia 1 | 54
Sensorineural Hearing Loss (disorder) 1 | 284
Severe mental retardation (I.Q. 20-34) 1 | 99
Skin hyperelastic 1 | 32
Soft skin 1 | 17
Thickened facial skin with coarse facial features 1 | 108
Thyroid Agenesis 1 | 5
Thyroid Hypoplasia 1 | 4
Thyroid cancer, follicular 1 | 8
Thyroid ectopia 1 | 2
Urinary tract obstruction 1 | 11
Variable expressivity 1 | 157
Velvety skin 1 | 17
Very poor growth 1 | 114
Vesico-Ureteral Reflux 1 | 33
Vesicoureteral reflux 1 | 32
Visual Impairment 1 | 174
Wide bregma sutures 1 | 46
Xerosis 1 | 75
end stage renal failure 1 | 8

Tissue

Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Urinary Tract 2 | 16,678
Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Liver and Pancreas 1 | 16,750
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230

Target Family

Transcription Factor 2 | 1,400

GO Process

positive regulation of metanep... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Paired box protein Pax-8 PAX8 Tbio Transcription Factor -2.64765 442.1 540