Development Level

Tbio 21 | 11,651
Tchem 7 | 1,388
Tclin 1 | 612

IMPC Phenotype

decreased mean platelet volume 2 | 25
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
decreased circulating phosphat... 1 | 27
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
increased heart weight 1 | 62
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 21 | 11,493
ovarian cancer 17 | 8,520
glioblastoma 14 | 5,792
osteosarcoma 14 | 7,950
Cancer 12 | 2,499
medulloblastoma, large-cell 12 | 6,241
psoriasis 11 | 6,694
lung cancer 10 | 4,740
atypical teratoid / rhabdoid tumor 9 | 5,112
acute quadriplegic myopathy 8 | 1,158
pancreatic cancer 8 | 2,398
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
adult high grade glioma 7 | 3,801
ependymoma 7 | 4,679
primary pancreatic ductal adenocarcinoma 7 | 1,109
Prostatic Neoplasms 6 | 495
dermatomyositis 6 | 966
diabetes mellitus 6 | 1,728
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Alzheimer's disease 5 | 658
Epilepsy 5 | 792
Neurodegenerative disease 5 | 414
Pick disease 5 | 1,894
Schizophrenia 5 | 1,160
astrocytoma 5 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
Amyotrophic lateral sclerosis 4 | 451
Astrocytoma, Pilocytic 4 | 3,081
Attention deficit hyperactivity disorder 4 | 278
Breast Neoplasms 4 | 445
Duchenne muscular dystrophy 4 | 601
Heart disease 4 | 306
Kidney disease 4 | 430
Mammary Neoplasms 4 | 425
Myocardial Ischemia 4 | 169
Nerve Degeneration 4 | 121
Vascular disease 4 | 319
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Atherosclerosis 3 | 291
Bipolar Disorder 3 | 666
Cardiomegaly 3 | 116
Dull intelligence 3 | 645
Dyspnea 3 | 76
Fibrosis 3 | 44
Heart failure 3 | 162
Hematuria 3 | 36
Highly variable clinical phenotype 3 | 150
Highly variable phenotype and severity 3 | 150
Highly variable phenotype, even within families 3 | 150
Hypertension 3 | 396
Insulin Resistance 3 | 72
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Major Depressive Disorder 3 | 301
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Neurodegenerative Disorders 3 | 79
Optic Atrophy 3 | 242
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Parkinson's disease 3 | 392
Phenotypic variability 3 | 150
Poor school performance 3 | 645
Pulmonary emphysema 3 | 48
Renal Cell Carcinoma 3 | 214
Seizures 3 | 596
Unipolar Depression 3 | 250
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
hypopigmented skin patch 3 | 59
pancreatic carcinoma 3 | 562
spina bifida 3 | 1,074
Abdominal Pain 2 | 98
Acute kidney injury 2 | 70
Chemical and Drug Induced Liver Injury 2 | 195
Chest Pain 2 | 38
Prominent back of the head 2 | 21
Prominent occiput 2 | 21
Squamous cell carcinoma 2 | 129
facioscapulohumeral dystrophy 2 | 288
sarcoidosis 2 | 370

Tissue

Digestive Tract 28 | 17,369
Female tissues 28 | 17,400
Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Endocrine System 27 | 18,159
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 15 | 12,091
Kinase 7 | 634
Enzyme 5 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Process

positive regulation of macroau... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WW domain-containing adapter protein with coiled-coil WAC Tbio Non-IDG -1.93384 84.9 87
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
5'-AMP-activated protein kinase catalytic subunit alpha-2 PRKAA2 Tchem Kinase -1.42705 21.1 603
Short coiled-coil protein SCOC Tbio Non-IDG -0.99386 9.57 48
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
G-protein-signaling modulator 1 GPSM1 Tbio Non-IDG -1.34464 28.6 132
Serine/threonine-protein kinase TBK1 TBK1 Tchem Kinase -2.76728 569.1 455
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 BNIP3 Tbio Non-IDG -2.51675 340.9 331
Hamartin TSC1 Tbio Non-IDG -2.25451 173.9 1622