Development Level

Tbio 17 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal kidney morphology 1 | 65
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased threshold for audito... 1 | 26
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased grip strength 1 | 41
polycystic kidney 1 | 15

Disease

Carcinoma 13 | 11,493
ovarian cancer 10 | 8,520
osteosarcoma 9 | 7,950
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
psoriasis 7 | 6,694
acute quadriplegic myopathy 6 | 1,158
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
lung cancer 6 | 4,740
atypical teratoid / rhabdoid tumor 5 | 5,112
malignant mesothelioma 5 | 3,232
Multiple myeloma 4 | 1,332
astrocytic glioma 4 | 2,597
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cleft Palate 2 | 271
Congenital clubfoot 2 | 109
Congenital hypoplasia of radius 2 | 23
Low set ears 2 | 181
Radial ray hypoplasia 2 | 23
Short stature 2 | 531
Stomach Neoplasms 2 | 300
Uranostaphyloschisis 2 | 167
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
Abnormal nasal morphology 1 | 16
Acrofacial dysostosis 1 | 8
Acute coronary syndrome 1 | 39
Alexithymia 1 | 16
Ascariasis 1 | 7
Asthenopia 1 | 10
Atrioventricular block 1 | 35
Bicornuate uterus 1 | 11
Bowen-Conradi syndrome 1 | 16
Broad hallux 1 | 29
Bunion 1 | 26
CREST Syndrome 1 | 16
Cervical vertebral abnormalities 1 | 6
Chancroid 1 | 8
Chronic fatigue syndrome 1 | 25
Cleft uvula 1 | 27
Convex nasal bridge 1 | 57
Depressed cheekbone 1 | 22
Dysbaric osteonecrosis 1 | 3
Enamel erosion 1 | 19
Flattening of the zygomatic bone 1 | 22
Full lower lip 1 | 64
Hallux Valgus 1 | 26
Hirschsprung disease 1 1 | 8
Hyperplasia of supraorbital margins 1 | 19
Hyperplasia of supraorbital ridge 1 | 19
Hypertrophy of supraorbital margins 1 | 19
Hypertrophy of supraorbital ridge 1 | 19
Hypoplasia of the zygomatic bone 1 | 22
Hypoplasia of thumb 1 | 26
Hypotrophic cheekbone 1 | 22
Koolen de Vries syndrome 1 | 18
Lens subluxation 1 | 12
Limited jaw mobility 1 | 5
Limited jaw opening 1 | 5
Macroorchidism 1 | 7
Mixed connective tissue disease 1 | 16
Myositis 1 | 30
Periorbital fullness 1 | 9
Prominent lower lip 1 | 64
Prominent nasal bridge 1 | 57
Prominent supraorbital ridges 1 | 19
Respiratory Distress Syndrome, Adult 1 | 40
SPINOCEREBELLAR ATAXIA 17 1 | 9
Schistosomiasis 1 | 35
Short phalanx of finger 1 | 32
Small cheekbone 1 | 22
Specific language impairment 1 | 34
Spinocerebellar ataxia type 17 1 | 7
Thumb absent or hypoplastic 1 | 9
Thumb aplasia 1 | 16
Treacher Collins syndrome 1 | 27
Triphalangeal thumb 1 | 9
Trismus 1 | 6
Waterhouse-Friderichsen syndrome 1 | 11
relapsing-remitting multiple sclerosis 1 | 18

Tissue

Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Liver and Pancreas 17 | 16,750
Respiratory system 17 | 16,393
Blood and immune system 16 | 16,909
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

positive regulation of mRNA sp... 19 | 19
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heat shock cognate 71 kDa protein HSPA8 Tchem Non-IDG -2.95379 881.0 741
Peroxiredoxin-6 PRDX6 Tbio Non-IDG -2.63290 435.3 425
Pre-mRNA-processing factor 19 PRPF19 Tbio Non-IDG -1.71524 54.2 234
Splicing factor 3B subunit 4 SF3B4 Tbio Non-IDG -1.44416 28.7 222
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.26305 200.9 189
Nuclear cap-binding protein subunit 1 NCBP1 Tbio Non-IDG -2.34134 207.7 172
Eukaryotic initiation factor 4A-III EIF4A3 Tbio Non-IDG -2.34087 210.7 164
Homeobox protein HMX2 HMX2 Tbio Transcription Factor -1.69094 35.7 144
U1 small nuclear ribonucleoprotein 70 kDa SNRNP70 Tbio Non-IDG -2.68581 440.9 144
DAZ-associated protein 1 DAZAP1 Tbio Non-IDG -1.36520 25.2 143