Development Level

Tbio 10 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal vertebrae morphology 2 | 18
decreased vertical activity 2 | 208
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal neural tube closure 1 | 46
abnormal pelvic girdle bone mo... 1 | 12
abnormal placenta size 1 | 20
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal scapula morphology 1 | 3
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
absent mammary gland 1 | 1
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased grip strength 1 | 116
decreased skeletal muscle mass 1 | 1
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating creatine... 1 | 5
increased monocyte cell number 1 | 63
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small heart 1 | 10
small kidney 1 | 16
small ovary 1 | 1
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small uterus 1 | 3
thin skin 1 | 2

Disease

Carcinoma 11 | 11,493
psoriasis 11 | 6,694
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 8 | 7,950
ovarian cancer 8 | 8,520
Cancer 6 | 2,499
glioblastoma 6 | 5,792
malignant mesothelioma 6 | 3,232
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
Breast Neoplasms 3 | 445
Failure to gain weight 3 | 365
Mammary Neoplasms 3 | 425
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
group 3 medulloblastoma 3 | 4,104
nephrosclerosis 3 | 333
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
'Bulging' epiphyses 2 | 3
Alkaline phosphatase serum increased 2 | 29
Alopecia 2 | 115
Alzheimer's disease 2 | 658
Bone pain 2 | 42
Carcinoma, Squamous Cell 2 | 110
Cerebrovascular disease 2 | 238
Chronic Lymphocytic Leukemia 2 | 262
Defective enamel matrix 2 | 35
Delayed epiphyseal ossification 2 | 10
Delayed maturation of end part of long bone 2 | 10
Dental Enamel Hypoplasia 2 | 43
Difficulty walking 2 | 28
Dysplasia of tooth enamel 2 | 35
Enlargement of the ankles 2 | 3
Enlargement of the wrists 2 | 5
Femoral bowing 2 | 20
Fibular bowing 2 | 5
Flat back of the head 2 | 26
Flat occiput 2 | 26
Frequent fractures 2 | 53
Frontal bossing 2 | 157
Genu varum 2 | 29
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hypercalcemia 2 | 59
Hyperparathyroidism 2 | 48
Hyperphosphatemia 2 | 32
Hypertension 2 | 396
Hypophosphatemia 2 | 40
Increased fracture rate 2 | 53
Increased serum parathyroid hormone 2 | 14
Irritation - emotion 2 | 68
Late tooth eruption 2 | 61
Liver cancer 2 | 604
Metaphyseal irregularity 2 | 23
Motor delay 2 | 147
Multiple Sclerosis 2 | 540
No development of motor milestones 2 | 147
Osteoarthritis 2 | 184
Osteomalacia 2 | 35
Poor growth 2 | 114
Protuberant abdomen 2 | 16
Rickets 2 | 49
Sparse bone trabeculae 2 | 3
Tetralogy of Fallot 2 | 63
Thin bony cortex 2 | 9
Thin dental enamel 2 | 35
Tibial bowing 2 | 19
Varying degree of multiple fractures 2 | 53
Very poor growth 2 | 114
Widely patent fontanels and sutures 2 | 12
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
spina bifida 2 | 1,074

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Blood and immune system 14 | 16,909
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

positive regulation of keratin... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Transcription factor Ovo-like 2 OVOL2 Tbio Transcription Factor -1.20117 17.4 110
Forkhead box protein C1 FOXC1 Tbio Transcription Factor -2.28586 201.8 314
Vitamin D3 receptor VDR Tclin Nuclear Receptor -3.62166 3805.7 575
Protein kinase C eta type PRKCH Tchem Kinase -1.79158 65.4 184
Core histone macro-H2A.1 H2AFY Tbio Non-IDG -1.78572 69.6 95
Nucleoside diphosphate kinase B NME1-NME2 Tbio Kinase -2.85003 1033.0 85
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417
Interleukin-20 IL20 Tbio Non-IDG 0.30 0.07 361
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.70628 492.9 68