Development Level

Tbio 8 | 11,445

IMPC Phenotype

abnormal heart morphology 1 | 162
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210

Disease

ovarian cancer 8 | 8,520
osteosarcoma 6 | 7,950
Carcinoma 5 | 11,493
non-small cell lung cancer 5 | 2,890
Cancer 4 | 2,499
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
nasopharyngeal carcinoma 4 | 1,058
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
invasive ductal carcinoma 3 | 2,951
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Bloom syndrome 2 | 29
Breast cancer 2 | 3,578
Colorectal Neoplasms 2 | 243
Multiple myeloma 2 | 1,332
Neurodegenerative disease 2 | 414
Waldenstrons macroglobulinemia 2 | 765
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
pancreatic cancer 2 | 2,398
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abdominal Pain 1 | 98
Achondroplasia 1 | 21
Adenocarcinoma of lung (disorder) 1 | 60
Anxiety 1 | 136
Anxiety disease 1 | 113
Ataxia telangiectasia 1 | 34
Axial hypotonia 1 | 46
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 1 | 13
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Beta thalassemia 1 | 16
Birthmark 1 | 35
Breast Neoplasms 1 | 445
Cafe-au-Lait Spots 1 | 37
Cell Transformation, Neoplastic 1 | 97
Cerebellar cyst 1 | 5
Colorectal cancer 1 | 25
Death in early adulthood 1 | 24
Degenerative brain disorder 1 | 100
Ectropion 1 | 38
Endometrial Neoplasms 1 | 55
Familial adenomatous polyposis 1 | 32
Fanconi anemia 1 | 56
Fatigue 1 | 182
Glioma 1 | 74
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Human immunodeficiency virus infectious disease 1 | 138
Hyperpigmented macules 1 | 42
IgG Deficiency 1 | 22
Immunoglobulin A deficiency (disorder) 1 | 19
Immunologic Deficiency Syndromes 1 | 113
Impaired Ig class-switch recombination (CSR) 1 | 3
Increased IgM levels 1 | 16
Increased gastric cancer 1 | 21
Increased susceptibility to bacterial infections 1 | 42
Intermittent migraine headaches 1 | 68
Iron Metabolism Disorders 1 | 5
Iron metabolism disease 1 | 20
Irritation - emotion 1 | 68
Kabuki syndrome 1 | 27
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Lymphadenopathy 1 | 62
Lymphoma 1 | 81
Lymphoma, Non-Hodgkin 1 | 24
Lynch syndrome 1 | 35
Malignant tumor of colon 1 | 19
Mammary Neoplasms 1 | 425
Microsatellite Instability 1 | 12
Microvillus inclusion disease 1 | 8
Migraine Disorders 1 | 76
Myocardial Reperfusion Injury 1 | 37
Nausea and vomiting 1 | 97
Neoplastic Cell Transformation 1 | 89
Nijmegen breakage syndrome 1 | 24
Pontocerebellar Hypoplasia Type 1 1 | 5
Poor head control 1 | 14
Progressive microcephaly 1 | 32
Prone to bacterial infection 1 | 42
Recurrent bacterial infection 1 | 42
Rhabdomyosarcoma 1 | 39
Sebaceous adenoma 1 | 26
Severe combined immunodeficiency 1 | 51
Supratentorial atrophy 1 | 94
Thalassemia 1 | 53
Weight decreased 1 | 103
X-linked cerebral adrenoleukodystrophy 1 | 116
nutritional deficiency disease 1 | 9

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 4 | 12,091
Enzyme 2 | 4,145
Epigenetic 2 | 242

GO Process

positive regulation of isotype... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Uracil-DNA glycosylase UNG Tbio Enzyme -2.82957 680.9 352
Telomere-associated protein RIF1 RIF1 Tbio Non-IDG -0.03141 1.27 98
DNA mismatch repair protein Msh6 MSH6 Tbio Epigenetic -2.72594 572.3 479
Exosome complex component MTR3 EXOSC6 Tbio Enzyme -0.78888 5.11 84
PAX-interacting protein 1 PAXIP1 Tbio Non-IDG -1.63612 44.7 79
Exosome complex component RRP40 EXOSC3 Tbio Non-IDG -1.19555 14.9 179