Development Level

Tbio 4 | 11,445

IMPC Phenotype

abnormal facial morphology 1 | 17
cleft palate 1 | 8
cyanosis 1 | 7
preweaning lethality, complete... 1 | 979

Disease

Cleft Palate 4 | 271
Uranostaphyloschisis 4 | 167
ovarian cancer 3 | 8,520
Abnormality of the urinary system 2 | 21
Alzheimer's disease 2 | 658
Anemia, Diamond-Blackfan 2 | 16
Anemia, Macrocytic 2 | 18
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Conduction disorder of the heart 2 | 79
Delayed Puberty 2 | 97
Diamond-Blackfan anemia 2 | 31
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Fatigue 2 | 182
Hand deformities 2 | 32
Hypoplastic mandible condyle 2 | 275
Intermittent migraine headaches 2 | 68
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Migraine Disorders 2 | 76
Pallor 2 | 40
diabetes mellitus 2 | 1,728
genital abnormal 2 | 17
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
mucosa-associated lymphoid tissue lymphoma 2 | 484
reproductive system abnormality 2 | 17
Anemia 1 | 365
Ankyloglossia 1 | 17
Anodontia 1 | 12
Anodontia of Permanent Dentition 1 | 6
Bamforth-Lazarus syndrome 1 | 4
Breast Neoplasms 1 | 445
Cleft lip and alveolus 1 | 4
Cleft palate with cleft lip 1 | 23
Cleft uvula 1 | 27
Craniofacial Abnormalities 1 | 151
Decreased projection of maxilla 1 | 66
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Deficiency of upper jaw bones 1 | 66
Dentin dysplasia 1 | 19
Dentinogenesis imperfecta 1 | 25
Developmental absence of tooth 1 | 7
Everted lower lip vermilion 1 | 54
Fine hair 1 | 42
Fragile nails 1 | 16
Fuhrmann syndrome 1 | 7
Gingival Overgrowth 1 | 36
Hypodontia 1 | 81
Hypodontia and nail dysgenesis 1 | 1
Hypohidrotic ectodermal dysplasia 1 | 15
Hypoplasia of the maxilla 1 | 66
Hypoplastic deciduous teeth 1 | 1
Hypoplastic enamel-onycholysis-hypohidrosis syndrome 1 | 1
Hypoplastic fingernails 1 | 11
Hypoplastic toenails 1 | 22
Hypotrophic maxilla 1 | 66
Koilonychia 1 | 7
Late tooth eruption 1 | 61
Mammary Neoplasms 1 | 425
Maxillary retrognathia 1 | 66
Mean cell volume increased 1 | 5
Microdontia (disorder) 1 | 59
Microdontia of primary teeth 1 | 1
Micronychia (disorder) 1 | 24
Missing more than six teeth 1 | 22
Myofibrillar myopathy 1 1 | 6
Myofibrillar myopathy 3 1 | 5
Nonsyndromic deafness 1 | 142
OROFACIAL CLEFT 5 1 | 1
Oligodontia 1 | 24
Parietal foramina 1 | 10
Peg-shaped teeth 1 | 8
Pick's disease 1 | 15
Pitting of nails 1 | 6
Pointed teeth 1 | 8
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
Protruding lower lip 1 | 54
Retrusion of upper jaw bones 1 | 66
Ridged fingernails 1 | 4
Ridged nails 1 | 14
Sparse hair 1 | 59
Stomach Neoplasms 1 | 300
Submucous cleft of hard palate 1 | 11
Thin toenails 1 | 1
Thin, sparse hair 1 | 59
Tooth Abnormalities 1 | 69
Tooth Agenesis, Familial 1 | 1
Tooth Agenesis, Selective, 1 1 | 2
Tooth absent 1 | 6
Tooth agenesis 1 | 44
Tooth and nail syndrome 1 | 1
Triphalangeal thumb 1 | 9
Witkop syndrome 1 | 1
Wolf-Hirschhorn syndrome 1 | 32
glioblastoma multiforme 1 | 142

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 3 | 12,091
Transcription Factor 1 | 1,400

GO Process

positive regulation of intrins... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
40S ribosomal protein S7 RPS7 Tbio Non-IDG -1.84836 69.5 112
60S ribosomal protein L11 RPL11 Tbio Non-IDG -2.23549 158.9 237