Development Level

Tbio 2 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal clavicle morphology 1 | 6
abnormal eyelid morphology 1 | 7
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal locomotor behavior 1 | 24
abnormal mandible morphology 1 | 2
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal snout morphology 1 | 23
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
absent teeth 1 | 3
decreased basophil cell number 1 | 16
decreased circulating alkaline... 1 | 46
decreased eosinophil cell numb... 1 | 24
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small thymus 1 | 16
thrombocytopenia 1 | 56

Disease

Carcinoma 5 | 11,493
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
cystic fibrosis 4 | 1,696
lung carcinoma 4 | 2,843
medulloblastoma, large-cell 4 | 6,241
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
invasive ductal carcinoma 3 | 2,951
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
Bone pain 2 | 42
Chronic Lymphocytic Leukemia 2 | 262
Leukemia, Lymphocytic, Chronic, B-Cell 2 | 34
Osteopetrosis 2 | 43
Vascular disease 2 | 319
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
ulcerative colitis 2 | 1,819
Abnormal blistering of the skin 1 | 54
Abnormal visual evoked potential 1 | 26
Abnormality of epiphysis morphology 1 | 39
Abnormality of hair consistency 1 | 5
Abnormality of hair curl pattern 1 | 5
Abnormality of hair texture 1 | 5
Abnormality of hair volume 1 | 5
Abnormality of the metaphyses 1 | 48
Abnormality of the ribs 1 | 32
Angiolipoma 1 | 3
Arthropathy 1 | 43
Autosomal recessive malignant osteopetrosis 1 | 4
Blister of skin 1 | 54
Blue rubber bleb nevus syndrome 1 | 1
Body Temperature Changes 1 | 10
Bone disease 1 | 10
Cherubism 1 | 13
Chronic rhinitis 1 | 7
Compression of optic nerve 1 | 7
Congenital arteriovenous malformation 1 | 8
Decreased bone mineral density Z score 1 | 31
Dental caries 1 | 164
Depersonalization disorder 1 | 4
Diabetic retinopathy 1 | 56
Epilepsy, Temporal Lobe 1 | 23
Exanthema 1 | 43
Facial paralysis 1 | 18
Failure of exfoliation of primary tooth 1 | 8
GLAUCOMA 3, PRIMARY CONGENITAL, A 1 | 4
Glomangioma 1 | 3
Hemangioma, Cavernous 1 | 20
Hemangiosarcoma 1 | 18
Hepatosplenomegaly 1 | 22
Hypercalcemia 1 | 59
Hypotension 1 | 82
Infantile malignant osteopetrosis 1 | 4
Intestinal hemorrhage NOS 1 | 2
Intestinal volvulus 1 | 8
Knee joint valgus deformity 1 | 56
Late tooth eruption 1 | 61
Liver Neoplasms, Experimental 1 | 59
Lymphadenopathy 1 | 62
Lytic lesion 1 | 32
Mouth Abnormalities 1 | 14
Multiple cutaneous and mucosal venous malformations 1 | 10
Multiple personality disorder 1 | 8
Multiple, subcutaneous nodules 1 | 53
Narrow thorax 1 | 53
Opsoclonus 1 | 5
Otitis Media 1 | 52
Ovarian Neoplasms 1 | 102
Paget's disease of bone 1 | 36
Pallor 1 | 40
Pathologic Neovascularization 1 | 6
Poor temperature regulation 1 | 10
Precocious exfoliation of primary tooth 1 | 11
Psoriatic arthritis 1 | 86
Pulmonary Fibrosis 1 | 106
Renal Cell Carcinoma 1 | 214
Retinopathy of prematurity 1 | 22
Root resorption 1 | 22
Rotting teeth 1 | 73
Skin bulla 1 | 54
Skull malformation 1 | 38
Subcutaneous nodule 1 | 53
Synovitis 1 | 78
Type 1 diabetes mellitus 1 | 109
Visceral angiomatosis 1 | 13
inflammatory breast cancer 1 | 286
ovarian neoplasm 1 | 99
primary congenital glaucoma 1 | 5

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192
Nervous System 5 | 16,725

Target Family

Kinase 3 | 634
Non-IDG 2 | 12,091
Enzyme 1 | 4,145

GO Process

positive regulation of intrace... 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase D2 PRKD2 Tchem Kinase -1.46203 23.4 417
Leucine-rich repeat serine/threonine-protein kinase 1 LRRK1 Tbio Kinase -1.33128 18.1 134
Neuroligin-1 NLGN1 Tbio Enzyme -1.96626 95.1 225
Angiopoietin-1 receptor TEK Tclin Kinase -3.00257 906.7 1009
Tumor necrosis factor ligand superfamily member 11 TNFSF11 Tclin Non-IDG -3.58408 4276.7 781
Fibroblast growth factor 1 FGF1 Tchem Non-IDG -3.21050 1645.9 514