Development Level

Tbio 7 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal pancreas morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210

Disease

Carcinoma 11 | 11,493
lung cancer 10 | 4,740
glioblastoma 9 | 5,792
ovarian cancer 9 | 8,520
psoriasis 8 | 6,694
atypical teratoid / rhabdoid tumor 6 | 5,112
lung carcinoma 6 | 2,843
osteosarcoma 6 | 7,950
ulcerative colitis 6 | 1,819
Cancer 5 | 2,499
Waldenstrons macroglobulinemia 5 | 765
ependymoma 5 | 4,679
hepatocellular carcinoma 5 | 547
pancreatic cancer 5 | 2,398
subependymal giant cell astrocytoma 5 | 2,287
Asthma 4 | 385
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Prostatic Neoplasms 4 | 495
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
gastric cancer 4 | 459
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
tuberculosis 4 | 2,010
Acquired immunodeficiency syndrome 3 | 197
Arthritis, Rheumatoid 3 | 174
Liver Cirrhosis, Experimental 3 | 769
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
acute myeloid leukemia 3 | 783
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
Abnormally-shaped vertebrae 2 | 31
Acquired scoliosis 2 | 281
Advanced bone age 2 | 35
Amphetamine-Related Disorders 2 | 74
Amyotrophic lateral sclerosis 2 | 451
Arsenic Poisoning 2 | 62
Arthritis 2 | 290
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Chronic obstructive pulmonary disease 2 | 184
Coronary artery disease 2 | 268
Crohn's disease 2 | 321
Curvature of spine 2 | 282
Depressive disorder 2 | 409
Dermatologic disorders 2 | 93
Down syndrome 2 | 499
Dysuria 2 | 26
Fatigue 2 | 182
Fever 2 | 138
Gastrointestinal system disease 2 | 54
Gaucher disease type 3 2 | 67
Hypersensitivity reaction type II disease 2 | 253
Increased Urinary Frequency 2 | 11
Kidney cancer 2 | 2,613
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Lymphoid leukemia 2 | 160
Lymphoma 2 | 81
Mental Depression 2 | 333
Nocturia 2 | 9
Skin Diseases 2 | 71
Suprapubic pain 2 | 8
Urgent desire to urinate 2 | 11
Urinary Incontinence 2 | 50
Urinary Tract Irritation 2 | 24
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
chronic kidney disease 2 | 90
chronic lymphosyte leukemia 2 | 204
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
esophageal cancer 2 | 22
fibroadenoma 2 | 559
group 3 medulloblastoma 2 | 4,104
head and neck cancer 2 | 271
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 8 | 12,091
Kinase 3 | 634
Enzyme 2 | 4,145
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

positive regulation of interle... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B Tclin Enzyme -2.13222 124.3 341
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.19489 157.7 218
Serine/threonine-protein kinase D2 PRKD2 Tchem Kinase -1.46203 23.4 417
Tumor necrosis factor ligand superfamily member 4 TNFSF4 Tbio Non-IDG -2.42277 289.2 439
SAM and SH3 domain-containing protein 3 SASH3 Tdark Non-IDG 0.95 0.08 38
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
C-C chemokine receptor type 2 CCR2 Tchem GPCR -3.06548 1112.4 530
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Receptor-interacting serine/threonine-protein kinase 2 RIPK2 Tchem Kinase -2.03990 107.3 474
cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D Tclin Enzyme -2.25701 166.5 341