Development Level

Tbio 20 | 11,445
Tchem 6 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal cecum morphology 1 | 7
abnormal embryo size 1 | 220
abnormal hair growth 1 | 10
abnormal vibrissa morphology 1 | 25
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
enlarged uterus 1 | 11
increased bone mineral content 1 | 108
increased circulating iron lev... 1 | 30
increased eosinophil cell numb... 1 | 11
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
small superior vagus ganglion 1 | 74

Disease

Carcinoma 19 | 11,493
ovarian cancer 18 | 8,520
psoriasis 15 | 6,694
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
Cancer 11 | 2,499
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
osteosarcoma 11 | 7,950
Influenza 10 | 142
juvenile dermatomyositis 9 | 1,187
Astrocytoma, Pilocytic 8 | 3,081
Breast cancer 8 | 3,578
dermatomyositis 8 | 966
Multiple Sclerosis 7 | 540
cutaneous lupus erythematosus 7 | 1,057
cystic fibrosis 7 | 1,696
group 4 medulloblastoma 7 | 1,855
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Arthritis 6 | 290
Hypersensitivity reaction type II disease 6 | 253
Kidney cancer 6 | 2,613
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
malignant mesothelioma 6 | 3,232
Asthma 5 | 385
Inflammation 5 | 120
Microphthalmia with limb anomalies 5 | 40
Systemic lupus erythematosus 5 | 194
astrocytic glioma 5 | 2,597
diabetes mellitus 5 | 1,728
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Atopic dermatitis 4 | 952
Autosomal recessive predisposition 4 | 1,442
Brain Injuries 4 | 65
Deglutition Disorders 4 | 132
Encephalitis 4 | 64
Gaucher disease type 1 4 | 180
Leishmaniasis 4 | 47
Liver disease 4 | 237
Melanoma 4 | 711
Rheumatoid arthritis 4 | 1,191
Vascular disease 4 | 319
active Crohn's disease 4 | 922
atypical teratoid / rhabdoid tumor 4 | 5,112
hepatocellular carcinoma 4 | 547
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
primary Sjogren syndrome 4 | 735
Allergic hypersensitivity disease 3 | 126
Bipolar Disorder 3 | 666
Brain disease 3 | 96
Cerebral atrophy 3 | 178
Crohn's disease 3 | 321
Dysarthria 3 | 192
Hepatitis 3 | 67
Hepatitis C 3 | 94
Highly variable clinical phenotype 3 | 150
Highly variable phenotype and severity 3 | 150
Highly variable phenotype, even within families 3 | 150
Human immunodeficiency virus infectious disease 3 | 138
Hyperreflexia 3 | 209
Hypogonadism 3 | 173
Hypoplasia of corpus callosum 3 | 90
Inflammatory bowel disease 3 | 151
Influenza, Human 3 | 51
Intellectual disability 3 | 1,016
Liver carcinoma 3 | 240
Lung disease 3 | 142
Malaria 3 | 160
Meningitis 3 | 67
Multiple myeloma 3 | 1,332
Muscle Spasticity 3 | 195
Obesity 3 | 678
Peritonitis 3 | 43
Phenotypic variability 3 | 150
Pick disease 3 | 1,894
Pneumonia 3 | 174
Progressive disorder 3 | 142
Schizophrenia 3 | 1,160
Short stature 3 | 531
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
breast carcinoma 3 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Atrophy of cerebellum 2 | 103
Cerebellar degeneration 2 | 103
Dystonia 2 | 164
Dystonic disease 2 | 106
Hepatitis B 2 | 108
Infratentorial atrophy 2 | 103

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678
Cardiovascular System 27 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 8 | 12,091
Transcription Factor 7 | 1,400
Kinase 3 | 634

GO Process

positive regulation of interfe... 28 | 28
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA-directed RNA polymerase III subunit RPC2 POLR3B Tbio Enzyme -1.25377 19.0 105
Zinc finger and BTB domain-containing protein 20 ZBTB20 Tbio Transcription Factor -2.14421 133.1 85
Interferon regulatory factor 5 IRF5 Tbio Transcription Factor -2.33923 241.0 400
High mobility group protein B2 HMGB2 Tbio Transcription Factor -1.52510 34.5 267
DNA-directed RNA polymerase III subunit RPC1 POLR3A Tbio Enzyme -2.25632 178.2 99
ATP-dependent RNA helicase DDX3X DDX3X Tchem Enzyme -2.32036 221.7 479
Serine/threonine-protein kinase RIO3 RIOK3 Tchem Kinase -1.08927 12.4 142
Interferon regulatory factor 1 IRF1 Tbio Transcription Factor -2.90315 827.7 366
Flotillin-1 FLOT1 Tbio Non-IDG -2.13455 128.8 277
Toll-like receptor 9 TLR9 Tclin Non-IDG -3.07216 1172.9 792