Development Level

Tbio 20 | 11,178
Tchem 9 | 1,885
Tclin 3 | 612
Tdark 1 | 6,569

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

decreased total body fat amoun... 3 | 207
decreased vertical activity 2 | 208
impaired glucose tolerance 2 | 75
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
enlarged heart 1 | 210
enlarged kidney 1 | 14
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
male infertility 1 | 123
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 16 | 11,192
medulloblastoma, large-cell 14 | 6,086
osteosarcoma 13 | 7,766
glioblastoma 12 | 5,635
psoriasis 12 | 6,514
adult high grade glioma 11 | 3,701
diabetes mellitus 10 | 1,683
ovarian cancer 10 | 8,297
ulcerative colitis 10 | 1,765
atypical teratoid / rhabdoid tumor 9 | 4,971
Breast cancer 8 | 3,469
astrocytic glioma 8 | 2,530
ependymoma 8 | 4,559
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,902
malignant mesothelioma 8 | 3,135
oligodendroglioma 8 | 2,768
primitive neuroectodermal tumor 8 | 2,957
Astrocytoma, Pilocytic 7 | 3,006
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,204
lung cancer 7 | 4,607
lung carcinoma 7 | 2,755
Cancer 6 | 2,388
Schizophrenia 6 | 1,136
non-small cell lung cancer 6 | 2,799
tuberculosis 6 | 1,963
Berylliosis 5 | 26
Diffuse cutaneous systemic sclerosis 5 | 17
Liver disease 5 | 227
Multiple Sclerosis, Susceptibility to 5 | 15
Narcolepsy 5 | 70
Narcolepsy-cataplexy 5 | 20
Obesity 5 | 655
Pick disease 5 | 1,856
Rheumatoid Arthritis, Systemic Juvenile 5 | 16
Rheumatoid arthritis 5 | 1,156
Sarcoidosis 1 5 | 14
Systemic lupus erythematosus 5 | 191
cystic fibrosis 5 | 1,629
follicular lymphoma 5 | 20
limited scleroderma 5 | 19
lung adenocarcinoma 5 | 2,627
non primary Sjogren syndrome sicca 5 | 861
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,911
sarcoidosis 5 | 357
Autosomal recessive predisposition 4 | 1,407
Bipolar Disorder 4 | 646
Hypertension 4 | 372
Seizures 4 | 584
active Crohn's disease 4 | 882
astrocytoma 4 | 1,113
colon cancer 4 | 1,428
cutaneous lupus erythematosus 4 | 1,016
group 3 medulloblastoma 4 | 4,002
group 4 medulloblastoma 4 | 1,806
interstitial cystitis 4 | 2,237
pancreatic cancer 4 | 2,322
subependymal giant cell astrocytoma 4 | 2,230
Addison's disease 3 | 30
Atopic dermatitis 3 | 915
Bradycardia 3 | 35
Constipation 3 | 174
Depressive disorder 3 | 401
Epilepsy 3 | 775
Heart failure 3 | 157
Hyperglycemia 3 | 134
Hypoglycemia 3 | 146
Juvenile rheumatoid arthritis 3 | 110
Major Depressive Disorder 3 | 293
Melanoma 3 | 689
Multiple Sclerosis 3 | 527
Pancreatitis 3 | 118
Prostatic Neoplasms 3 | 472
Unipolar Depression 3 | 244
Weight decreased 3 | 101
breast carcinoma 3 | 1,589
dermatomyositis 3 | 941
esophageal adenocarcinoma 3 | 696
invasive ductal carcinoma 3 | 2,867
maturity-onset diabetes of the young 3 | 32
Acromegaly 2 | 48
Adenoma 2 | 159
Alzheimer's disease 2 | 640
Cholestasis 2 | 154
Diabetes Mellitus, Non-Insulin-Dependent 2 | 140
Diabetes Mellitus, Type 2 2 | 136
Diarrhea 2 | 245
Failure to gain weight 2 | 359
Hypersensitivity reaction type II disease 2 | 245
Mood Disorders 2 | 181
Pancreatic Neoplasm 2 | 82
Pancreatic Neoplasms 2 | 82
Parkinson's disease 2 | 378
Pediatric failure to thrive 2 | 359
Short nose 2 | 127
Skin cancer 2 | 451
Small nose 2 | 127
Vasculitis 2 | 76
Waldenstrons macroglobulinemia 2 | 742
atypical teratoid/rhabdoid tumor 2 | 349

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Liver and Pancreas 29 | 16,750
Female tissues 28 | 17,400
Male tissues 27 | 17,142
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Nervous System 26 | 16,725
Urinary Tract 26 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 5 | 4,145
Ion Channel 3 | 344
Transcription Factor 3 | 1,400
GPCR 2 | 408
Nuclear Receptor 1 | 48

GO Process

positive regulation of insulin... 33 | 33
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631