Development Level

Tbio 22 | 11,445
Tchem 15 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased vertical activity 3 | 208
abnormal seminal vesicle morph... 2 | 114
decreased neutrophil cell numb... 2 | 42
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased bone mineral content 2 | 108
increased fasted circulating g... 2 | 76
increased lymphocyte cell numb... 2 | 32
abnormal gait 1 | 69
abnormal pancreas morphology 1 | 13
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased cardiac stroke volum... 1 | 6
decreased heart rate 1 | 18
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
enlarged uterus 1 | 11
hypoactivity 1 | 132
increased IgG2b level 1 | 1
increased bone mineral density 1 | 72
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24

Disease

Carcinoma 26 | 11,493
osteosarcoma 23 | 7,950
diabetes mellitus 20 | 1,728
ovarian cancer 19 | 8,520
medulloblastoma, large-cell 18 | 6,241
psoriasis 17 | 6,694
Obesity 16 | 678
lung carcinoma 13 | 2,843
group 3 medulloblastoma 12 | 4,104
primitive neuroectodermal tumor 12 | 3,035
Cancer 11 | 2,499
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
adult high grade glioma 10 | 3,801
astrocytic glioma 10 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
malignant mesothelioma 10 | 3,232
Astrocytoma, Pilocytic 9 | 3,081
Hyperglycemia 9 | 137
ependymoma 9 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
oligodendroglioma 9 | 2,850
pancreatic cancer 9 | 2,398
Autosomal recessive predisposition 8 | 1,442
Liver Cirrhosis, Experimental 8 | 769
breast carcinoma 8 | 1,638
group 4 medulloblastoma 8 | 1,855
lung adenocarcinoma 8 | 2,716
Breast cancer 7 | 3,578
Diabetes Mellitus, Non-Insulin-Dependent 7 | 145
Hypoglycemia 7 | 152
Rheumatoid arthritis 7 | 1,191
Seizures 7 | 596
interstitial cystitis 7 | 2,312
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
subependymal giant cell astrocytoma 7 | 2,287
ulcerative colitis 7 | 1,819
Diabetes Mellitus, Type 2 6 | 142
Kidney cancer 6 | 2,613
Multiple myeloma 6 | 1,332
Type 2 diabetes mellitus 6 | 272
ductal carcinoma in situ 6 | 1,745
pituitary cancer 6 | 1,972
Depressive disorder 5 | 409
Diabetes Mellitus, Experimental 5 | 108
Diabetes Mellitus, Noninsulin-Dependent 5 | 31
Duchenne muscular dystrophy 5 | 601
Epilepsy 5 | 792
Hyperinsulinism 5 | 133
Intellectual disability 5 | 1,016
Polycystic ovary syndrome 5 | 360
Schizophrenia 5 | 1,160
acute quadriplegic myopathy 5 | 1,158
cystic fibrosis 5 | 1,696
juvenile dermatomyositis 5 | 1,187
maturity-onset diabetes of the young 5 | 32
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Acquired metabolic disease 4 | 336
Adenoma 4 | 167
Anemia 4 | 365
Atopic dermatitis 4 | 952
Bipolar Disorder 4 | 666
Dull intelligence 4 | 645
Fatty liver disease 4 | 103
Hypertension 4 | 396
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle Weakness 4 | 170
Myocardial Ischemia 4 | 169
Poor school performance 4 | 645
acute myeloid leukemia 4 | 783
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
dermatomyositis 4 | 966
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
primary pancreatic ductal adenocarcinoma 4 | 1,109
Asthma 3 | 385
Cushing's syndrome 3 | 48
Down syndrome 3 | 499
Failure to gain weight 3 | 365
Liver carcinoma 3 | 240
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Unipolar Depression 3 | 250
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
medulloblastoma 3 | 720

Tissue

Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Respiratory system 40 | 16,393
Blood and immune system 39 | 16,909
Liver and Pancreas 39 | 16,750
Nervous System 39 | 16,725
Skin and soft tissues 38 | 17,230
Male tissues 37 | 17,142
Urinary Tract 37 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 7 | 4,145
Kinase 7 | 634
GPCR 4 | 408
Transcription Factor 4 | 1,400
Nuclear Receptor 2 | 48
Epigenetic 1 | 242
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

positive regulation of insulin... 42 | 42
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Tyrosine-protein kinase Blk BLK Tchem Kinase -1.88753 81.6 418
Calpain-10 CAPN10 Tbio Non-IDG -2.27096 197.8 112
Acetoacetyl-CoA synthetase AACS Tbio Enzyme -2.09428 127.1 97
Stress-associated endoplasmic reticulum protein 1 SERP1 Tbio Non-IDG -1.37994 31.0 79
Calcium uniporter protein, mitochondrial MCU Tbio Ion Channel -2.67075 458.1 25
Zinc transporter 8 SLC30A8 Tbio Transporter -2.20313 168.0 122
Glutamate dehydrogenase 1, mitochondrial GLUD1 Tbio Enzyme -2.39787 257.7 148
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Neuroligin-2 NLGN2 Tbio Enzyme -1.71616 50.4 77