Development Level

Tchem 5 | 1,598
Tbio 2 | 11,445
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased bone mineral content 1 | 151
decreased circulating calcium ... 1 | 36
decreased lean body mass 1 | 135
decreased threshold for audito... 1 | 26
hyperactivity 1 | 148
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Cancer 5 | 2,499
Carcinoma 5 | 11,493
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Alcoholic Intoxication, Chronic 2 | 289
Amyotrophic lateral sclerosis 2 | 451
Cataract 2 | 297
Depressive disorder 2 | 409
Hypercalcemia 2 | 59
Hypercalciuria 2 | 27
Hyperparathyroidism 2 | 48
Hypoparathyroidism 2 | 41
Hypophosphatemia 2 | 40
Lens Opacities 2 | 231
Metaphyseal dysplasia 2 | 11
Osteoporosis 2 | 363
Osteosclerosis 2 | 31
Pseudohypoparathyroidism 2 | 18
Rickets 2 | 49
Schizophrenia 2 | 1,160
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
tuberculosis 2 | 2,010
Abnormal development of end part of bone 1 | 14
Abnormality of position of teeth 1 | 8
Abnormality of the acetabulum 1 | 2
Acquired cubitus valgus 1 | 18
Acrodysostosis 1 | 12
Aplastic clavicles 1 | 6
Blount's disease 1 | 3
Bone Diseases, Endocrine 1 | 2
Bone Resorption 1 | 8
Chromosome 3q29 microdeletion syndrome 1 | 11
Chromosome 3q29 microduplication syndrome 1 | 6
Clubbed Fingers 1 | 4
Cornelia de Lange syndrome 1 | 21
Diffuse, symmetrical osteosclerosis 1 | 5
Enchondromatosis 1 | 5
Epiphyseal dysplasia 1 | 14
Exostosis 1 | 15
Flexion contracture of hip 1 | 10
Gait, Shuffling 1 | 8
Glucocorticoid Induced Osteoporosis 1 | 4
Hereditary spastic paraplegia 14 1 | 1
Hyperostosis 1 | 18
Hyperparathyroidism, Secondary 1 | 7
Hyperphosphaturia 1 | 21
Hypervitaminosis D 1 | 8
Hypogonadal Osteoporosis in Males 1 | 4
Hypoparathyroidism familial isolated 1 | 3
Hypoparathyroidism, Familial Isolated 1 | 3
Increased bone density in skeletal bones 1 | 5
Inflammatory bowel disease 19 1 | 2
Laryngeal calcification 1 | 2
Lethal skeletal dysplasia 1 | 6
Lewy body dementia 1 | 4
Leydig cell tumor 1 | 9
Maffucci syndrome 1 | 6
Mesomelia 1 | 8
Metaphyseal chondrodysplasia 1 | 7
Metaphyseal cupping 1 | 10
Metaphyseal irregularity 1 | 23
Misalignment of teeth 1 | 8
Multiple Endocrine Neoplasia Type 1 1 | 29
Multiple, subcutaneous nodules 1 | 53
Narrow pelvis 1 | 6
Onset in middle age 1 | 4
Osteitis fibrosa 1 | 7
Osteoporosis, Postmenopausal 1 | 6
PARKINSON DISEASE 15, AUTOSOMAL RECESSIVE (disorder) 1 | 2
PARKINSON DISEASE 19, JUVENILE-ONSET 1 | 10
Paranoia 1 | 20
Parathyroid Adenoma 1 | 19
Protuberant abdomen 1 | 16
Sacral agenesis 1 | 3
Short limb dwarfism recognizable at birth 1 | 9
Short phalanx of finger 1 | 32
Short tubular bones 1 | 22
Spade-like hand 1 | 16
Splayed metaphyses 1 | 19
Split hand-foot malformation 1 | 18
Square iliac bones 1 | 4
Subcutaneous nodule 1 | 53
Thrombosis 1 | 46
Urine phosphorous concentration above normal 1 | 21
Young onset Parkinson disease 1 | 10
autosomal recessive early-onset Parkinson disease 15 1 | 2

Tissue

Endocrine System 8 | 18,159
Skin and soft tissues 8 | 17,230
Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Female tissues 6 | 17,400
Cardiovascular System 5 | 15,192
Respiratory system 5 | 16,393
Urinary Tract 5 | 16,678

Target Family

GPCR 5 | 408
Non-IDG 3 | 12,091

GO Process

positive regulation of inosito... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Platelet-activating factor receptor PTAFR Tchem GPCR -2.02420 116.1 134
Pituitary adenylate cyclase-activating polypeptide type I receptor ADCYAP1R1 Tchem GPCR -1.98111 94.8 184
Neurotensin receptor type 1 NTSR1 Tchem GPCR -2.94526 841.8 215
Natural killer cell receptor 2B4 CD244 Tbio Non-IDG -2.31642 197.2 481
Parathyroid hormone PTH Tbio Non-IDG -4.31704 21156.6 1312
Alpha-synuclein SNCA Tchem Non-IDG -3.63937 4224.9 1813
Parathyroid hormone/parathyroid hormone-related peptide receptor PTH1R Tclin GPCR -2.77825 573.5 287
Proto-oncogene Mas MAS1 Tchem GPCR -2.00943 96.9 232