Development Level

Tbio 8 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal glucose homeostasis 1 | 4
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
thrombocytosis 1 | 27

Disease

Carcinoma 11 | 11,493
Cancer 10 | 2,499
Obesity 10 | 678
diabetes mellitus 10 | 1,728
ovarian cancer 9 | 8,520
Hyperglycemia 8 | 137
Hyperinsulinism 8 | 133
psoriasis 8 | 6,694
Insulin Resistance 7 | 72
Polycystic ovary syndrome 7 | 360
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung cancer 7 | 4,740
Alzheimer's disease 6 | 658
Breast cancer 6 | 3,578
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
breast carcinoma 6 | 1,638
ependymoma 6 | 4,679
invasive ductal carcinoma 6 | 2,951
Adenoma 5 | 167
Anemia 5 | 365
Cognitive delay 5 | 608
Diabetes Mellitus, Experimental 5 | 108
Diabetes Mellitus, Noninsulin-Dependent 5 | 31
Diabetes Mellitus, Type 2 5 | 142
Epilepsy 5 | 792
Fetal Growth Retardation 5 | 189
Global developmental delay 5 | 608
Hypoglycemia 5 | 152
Hypothyroidism 5 | 122
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Liver disease 5 | 237
Low Birth Weights 5 | 69
Mental and motor retardation 5 | 608
Seizures 5 | 596
Small for gestational age (disorder) 5 | 69
adrenocortical carcinoma 5 | 1,428
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
Acromegaly 4 | 51
Alzheimer Disease 4 | 83
Arthritis 4 | 290
Atherosclerosis 4 | 291
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Blepharoptosis 4 | 231
Coronary artery disease 4 | 268
Fatty liver disease 4 | 103
Heart disease 4 | 306
Hypertension 4 | 396
Hyperthyroidism 4 | 53
Intellectual disability 4 | 1,016
Kidney disease 4 | 430
Lipid metabolism disorder 4 | 114
Motor delay 4 | 147
Neuropathy 4 | 261
No development of motor milestones 4 | 147
Osteoporosis 4 | 363
Peripheral Neuropathy 4 | 134
Prostatic Neoplasms 4 | 495
Weight decreased 4 | 103
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
Atopic dermatitis 3 | 952
Brain disease 3 | 96
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Cardiomegaly 3 | 116
Curvature of digit 3 | 57
Delayed bone age 3 | 136
Dull intelligence 3 | 645
Failure to gain weight 3 | 365
Hyperandrogenism 3 | 34
Hyperparathyroidism 3 | 48
Hypersensitivity reaction type II disease 3 | 253
Hypoplastic mandible condyle 3 | 275
Kidney cancer 3 | 2,613
Lewy Body Disease 3 | 21
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Lung disease 3 | 142
Mammary Neoplasms 3 | 425
Myopathy 3 | 185
Parkinson Disease 3 | 64
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Poor school performance 3 | 645
Radially deviated fingers 3 | 38
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
group 3 medulloblastoma 3 | 4,104
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Skin and soft tissues 15 | 17,230
Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Urinary Tract 14 | 16,678

Target Family

Non-IDG 9 | 12,091
Kinase 5 | 634
Nuclear Receptor 1 | 48

GO Process

positive regulation of glycoge... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Steroid hormone receptor ERR2 ESRRB Tchem Nuclear Receptor -1.95523 86.9 173
Sorbin and SH3 domain-containing protein 1 SORBS1 Tbio Non-IDG -1.57341 40.2 224
Insulin receptor INSR Tclin Kinase -2.50045 306.8 1417
Complement C1q tumor necrosis factor-related protein 2 C1QTNF2 Tdark Non-IDG -0.36938 3.10 225
Insulin receptor substrate 2 IRS2 Tbio Non-IDG -2.64133 414.7 227
Parathyroid hormone PTH Tbio Non-IDG -4.31704 21156.6 1312
Insulin-like growth factor II IGF2 Tbio Non-IDG -3.65750 4465.3 457
Insulin INS Tbio Non-IDG -5.17849 146933.7 2197
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565
RAC-beta serine/threonine-protein kinase AKT2 Tchem Kinase -2.60567 332.5 1173