Development Level

Tbio 31 | 11,445
Tchem 3 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 2 | 298
decreased body weight 2 | 161
embryonic lethality prior to o... 2 | 239
increased startle reflex 2 | 112
abnormal kidney morphology 1 | 65
abnormal posture 1 | 2
absent pinna reflex 1 | 23
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 22 | 8,520
Carcinoma 18 | 11,493
osteosarcoma 18 | 7,950
psoriasis 16 | 6,694
lung cancer 15 | 4,740
group 3 medulloblastoma 12 | 4,104
medulloblastoma, large-cell 12 | 6,241
lung adenocarcinoma 11 | 2,716
Multiple myeloma 10 | 1,332
glioblastoma 10 | 5,792
Breast cancer 9 | 3,578
Cancer 9 | 2,499
invasive ductal carcinoma 9 | 2,951
malignant mesothelioma 9 | 3,232
atypical teratoid / rhabdoid tumor 8 | 5,112
colon cancer 8 | 1,478
primitive neuroectodermal tumor 8 | 3,035
Kidney cancer 7 | 2,613
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
non-small cell lung cancer 7 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pediatric high grade glioma 7 | 1,064
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
ependymoma 6 | 4,679
pancreatic cancer 6 | 2,398
Broad flat nasal bridge 5 | 236
Dull intelligence 5 | 645
Hypoplastic mandible condyle 5 | 275
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mandibular hypoplasia 5 | 275
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Micrognathism 5 | 275
Nasal bridge wide 5 | 236
Pick disease 5 | 1,894
Poor school performance 5 | 645
Rheumatoid arthritis 5 | 1,191
Small head 5 | 374
acute myeloid leukemia 5 | 783
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
oligodendroglioma 5 | 2,850
Epilepsy 4 | 792
Muscle hypotonia 4 | 571
Seizures 4 | 596
Short stature 4 | 531
Strabismus 4 | 270
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
hepatocellular carcinoma 4 | 547
pancreatic carcinoma 4 | 562
tuberculosis 4 | 2,010
Agenesis of corpus callosum 3 | 83
Angle class 2 malocclusion 3 | 57
Angle class 3 malocclusion 3 | 57
Astrocytoma, Pilocytic 3 | 3,081
Autistic Disorder 3 | 364
Autosomal recessive predisposition 3 | 1,442
Cataract 3 | 297
Cleft Palate 3 | 271
Cognitive delay 3 | 608
Craniofacial Abnormalities 3 | 151
Cryptorchidism 3 | 296
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Down syndrome 3 | 499
Downward slant of palpebral fissure 3 | 158
Global developmental delay 3 | 608
Hereditary spherocytosis type 5 3 | 12
Hyperkyphosis 3 | 111
Hypoplasia of the maxilla 3 | 66
Hypotrophic maxilla 3 | 66
Kyphosis deformity of spine 3 | 114
Lens Opacities 3 | 231
Long philtrum 3 | 137
Low Vision 3 | 174
Malocclusion 3 | 57
Maxillary retrognathia 3 | 66
Mental and motor retardation 3 | 608
Patent ductus arteriosus 3 | 90
Postnatal growth retardation 3 | 57
Retrusion of upper jaw bones 3 | 66
Schizophrenia 3 | 1,160
Sensorineural Hearing Loss (disorder) 3 | 284
Tremor 3 | 113
Uranostaphyloschisis 3 | 167
Visual Impairment 3 | 174
atypical teratoid/rhabdoid tumor 3 | 357
cutaneous lupus erythematosus 3 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
non-small cell lung carcinoma 3 | 317
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074

Tissue

Blood and immune system 36 | 16,909
Cardiovascular System 36 | 15,192
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678

Target Family

Enzyme 17 | 4,145
Non-IDG 14 | 12,091
Epigenetic 4 | 242
Transporter 1 | 473

GO Process

positive regulation of gene ex... 36 | 36
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase BAZ1B BAZ1B Tbio Epigenetic -1.45627 32.0 155
Sugar transporter SWEET1 SLC50A1 Tbio Transporter -2.23661 169.6 56
DNA-directed RNA polymerases I, II, and III subunit RPABC2 POLR2F Tbio Enzyme -1.13403 13.9 68
DNA-directed RNA polymerases I, II, and III subunit RPABC4 POLR2K Tbio Enzyme -0.90716 7.36 65
DNA-directed RNA polymerases I, II, and III subunit RPABC3 POLR2H Tbio Enzyme -1.13403 13.5 180
DNA-directed RNA polymerase I subunit RPA34 CD3EAP Tbio Enzyme -1.13064 13.8 209
DNA-directed RNA polymerases I, II, and III subunit RPABC5 POLR2L Tbio Enzyme -1.12793 13.8 66
Protein DEK DEK Tbio Non-IDG -2.24912 193.2 183
TATA box-binding protein-associated factor RNA polymerase I subunit A TAF1A Tbio Enzyme -0.84154 6.46 161
DNA excision repair protein ERCC-6 ERCC6 Tbio Non-IDG -2.31776 361.5 163