Development Level

Tbio 201 | 11,445
Tchem 64 | 1,598
Tclin 28 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 17 | 979
preweaning lethality, incomple... 11 | 499
embryonic lethality prior to t... 9 | 278
enlarged heart 9 | 210
abnormal heart morphology 6 | 162
decreased lymphocyte cell numb... 6 | 83
increased circulating alkaline... 6 | 122
abnormal embryo size 5 | 220
cataract 5 | 92
decreased circulating HDL chol... 5 | 68
decreased total body fat amoun... 5 | 207
small superior vagus ganglion 5 | 74
decreased circulating LDL chol... 4 | 38
decreased circulating choleste... 4 | 93
decreased mean corpuscular vol... 4 | 79
decreased vertical activity 4 | 208
impaired glucose tolerance 4 | 75
abnormal bone structure 3 | 187
abnormal eye morphology 3 | 68
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
decreased grip strength 3 | 116
decreased leukocyte cell numbe... 3 | 73
decreased spleen weight 3 | 10
embryonic lethality prior to o... 3 | 239
enlarged uterus 3 | 11
hyperactivity 3 | 148
increased circulating chloride... 3 | 41
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased neutrophil cell numb... 3 | 46
increased red blood cell distr... 3 | 34
short tibia 3 | 97
abnormal behavior 2 | 298
abnormal cecum morphology 2 | 7
abnormal cranium morphology 2 | 36
abnormal facial morphology 2 | 17
abnormal forebrain development 2 | 20
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
abnormal spleen morphology 2 | 55
abnormal thymus morphology 2 | 7
decreased T cell number 2 | 15
decreased circulating alkaline... 2 | 46
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased circulating glycerol... 2 | 16
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 50
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
enlarged spleen 2 | 41
hemorrhage 2 | 23
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 96
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
prenatal lethality prior to he... 2 | 87
small thymus 2 | 16
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal lung morphology 1 | 26
abnormal tooth morphology 1 | 24
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating creatine... 1 | 4
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased mean corpuscular hem... 1 | 31
decreased pulmonary respirator... 1 | 5
enlarged stomach 1 | 2
increased aggression 1 | 4
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating creatine... 1 | 5
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased startle reflex 1 | 112
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
tremors 1 | 39

Disease

Carcinoma 187 | 11,493
psoriasis 163 | 6,694
ovarian cancer 161 | 8,520
Cancer 140 | 2,499
osteosarcoma 138 | 7,950
glioblastoma 131 | 5,792
lung cancer 130 | 4,740
medulloblastoma, large-cell 118 | 6,241
atypical teratoid / rhabdoid tumor 96 | 5,112
malignant mesothelioma 95 | 3,232
Breast cancer 94 | 3,578
ependymoma 92 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 85 | 3,291
invasive ductal carcinoma 82 | 2,951
adult high grade glioma 78 | 3,801
group 3 medulloblastoma 78 | 4,104
pancreatic cancer 78 | 2,398
Astrocytoma, Pilocytic 77 | 3,081
Schizophrenia 73 | 1,160
lung carcinoma 73 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 72 | 2,955
lung adenocarcinoma 72 | 2,716
non-small cell lung cancer 72 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 71 | 2,989
interstitial cystitis 67 | 2,312
oligodendroglioma 66 | 2,850
Kidney cancer 64 | 2,613
cystic fibrosis 64 | 1,696
ulcerative colitis 60 | 1,819
diabetes mellitus 58 | 1,728
primitive neuroectodermal tumor 57 | 3,035
ductal carcinoma in situ 56 | 1,745
astrocytic glioma 54 | 2,597
pituitary cancer 54 | 1,972
breast carcinoma 52 | 1,638
tuberculosis 49 | 2,010
colon cancer 46 | 1,478
cutaneous lupus erythematosus 46 | 1,057
group 4 medulloblastoma 46 | 1,855
Prostatic Neoplasms 44 | 495
Rheumatoid arthritis 44 | 1,191
subependymal giant cell astrocytoma 43 | 2,287
Bipolar Disorder 41 | 666
Breast Neoplasms 40 | 445
Autosomal recessive predisposition 39 | 1,442
Mammary Neoplasms 39 | 425
Obesity 38 | 678
Vascular disease 38 | 319
adrenocortical carcinoma 38 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,962
Pick disease 37 | 1,894
juvenile dermatomyositis 36 | 1,187
Depressive disorder 35 | 409
Kidney disease 35 | 430
acute quadriplegic myopathy 34 | 1,158
primary pancreatic ductal adenocarcinoma 34 | 1,109
Alzheimer's disease 33 | 658
Atopic dermatitis 33 | 952
Hypertension 33 | 396
astrocytoma 33 | 1,146
Intellectual disability 32 | 1,016
Endometriosis 31 | 540
Osteoporosis 31 | 363
Multiple myeloma 30 | 1,332
dermatomyositis 30 | 966
Liver Cirrhosis, Experimental 29 | 769
Mental Depression 29 | 333
Short stature 29 | 531
Melanoma 28 | 711
Hypertensive disease 27 | 292
Arthritis 26 | 290
Heart disease 26 | 306
Major Depressive Disorder 26 | 301
nasopharyngeal carcinoma 26 | 1,058
spina bifida 26 | 1,074
Dull intelligence 25 | 645
Liver carcinoma 25 | 240
Low intelligence 25 | 645
Mental Retardation 25 | 645
Mental deficiency 25 | 645
Multiple Sclerosis 25 | 540
Parkinson's disease 25 | 392
Poor school performance 25 | 645
Anemia 24 | 365
Atherosclerosis 24 | 291
Carcinoma, Hepatocellular 24 | 228
Epilepsy 24 | 792
Neoplasm Invasiveness 24 | 161
Seizures 24 | 596
autosomal dominant Emery-Dreifuss muscular dystrophy 24 | 510
Asthma 23 | 385
Cerebrovascular disease 23 | 238
Liver disease 23 | 237
Lung Neoplasms 23 | 232
Neoplasm Metastasis 23 | 168
Unipolar Depression 23 | 250
Waldenstrons macroglobulinemia 23 | 765
active Crohn's disease 23 | 922
active ulcerative colitis 23 | 764
pancreatic carcinoma 23 | 562

Tissue

Endocrine System 293 | 18,159
Skin and soft tissues 292 | 17,230
Digestive Tract 290 | 17,369
Female tissues 288 | 17,400
Blood and immune system 286 | 16,909
Liver and Pancreas 283 | 16,750
Urinary Tract 282 | 16,678
Male tissues 281 | 17,142
Respiratory system 277 | 16,393
Nervous System 276 | 16,725
Cardiovascular System 250 | 15,192

Target Family

Non-IDG 160 | 12,091
Transcription Factor 48 | 1,400
Enzyme 33 | 4,145
Kinase 32 | 634
GPCR 7 | 408
Epigenetic 6 | 242
Nuclear Receptor 4 | 48
Transporter 3 | 473
Ion Channel 2 | 344
TF/Epigenetic 2 | 38

GO Process

positive regulation of gene ex... 297 | 297
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anterior gradient protein 2 homolog AGR2 Tbio Non-IDG -2.07496 136.6 594
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Homeobox protein ARX ARX Tbio Transcription Factor -2.21255 163.7 328
Zinc finger protein 580 ZNF580 Tbio Transcription Factor -1.04597 11.4 74
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Plakophilin-3 PKP3 Tbio Non-IDG -1.37372 26.0 200
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.13442 140.5 524
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236