Development Level

Tbio 17 | 11,445
Tclin 5 | 613
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal iris morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased circulating glucose ... 1 | 24
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
mydriasis 1 | 6
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

ovarian cancer 22 | 8,520
Carcinoma 16 | 11,493
Cancer 14 | 2,499
osteosarcoma 14 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
psoriasis 13 | 6,694
atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 12 | 5,792
medulloblastoma, large-cell 11 | 6,241
Breast cancer 10 | 3,578
ependymoma 10 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
Kidney cancer 9 | 2,613
adult high grade glioma 9 | 3,801
interstitial cystitis 9 | 2,312
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
pancreatic cancer 9 | 2,398
lung cancer 8 | 4,740
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
diabetes mellitus 6 | 1,728
group 3 medulloblastoma 6 | 4,104
malignant mesothelioma 6 | 3,232
primitive neuroectodermal tumor 6 | 3,035
Glaucoma 5 | 239
Kidney disease 5 | 430
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary pancreatic ductal adenocarcinoma 5 | 1,109
tuberculosis 5 | 2,010
Breast Neoplasms 4 | 445
Depressive disorder 4 | 409
Endometriosis 4 | 540
Liver Cirrhosis, Experimental 4 | 769
Mammary Neoplasms 4 | 425
Mental Depression 4 | 333
Retinopathy of prematurity 4 | 22
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,057
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
interstitial lung disease 4 | 298
juvenile dermatomyositis 4 | 1,187
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Adenocarcinoma 3 | 122
Bipolar Disorder 3 | 666
Carcinoma, Hepatocellular 3 | 228
Colorectal Neoplasms 3 | 243
Coronary artery disease 3 | 268
Diabetic retinopathy 3 | 56
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Epilepsy, Temporal Lobe 3 | 23
Hemangioma 3 | 69
Hemangiosarcoma 3 | 18
Hypertension 3 | 396
Liver carcinoma 3 | 240
Major Depressive Disorder 3 | 301
Melanoma 3 | 711
Neovascularization, Pathologic 3 | 6
Pathologic Neovascularization 3 | 6
Prostatic Neoplasms 3 | 495
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Skin cancer 3 | 469
Vascular disease 3 | 319
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484
urothelial carcinoma 3 | 318
Adenoma 2 | 167
Atherosclerosis 2 | 291
Cerebrovascular disease 2 | 238
Heart disease 2 | 306
Liver Cirrhosis 2 | 181
Liver cancer 2 | 604
Mood Disorders 2 | 184
Myocardial Ischemia 2 | 169
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Reperfusion Injury 2 | 86
Unipolar Depression 2 | 250
Waldenstrons macroglobulinemia 2 | 765
astrocytoma 2 | 1,146
glioblastoma multiforme 2 | 142
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468

Tissue

Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678
Blood and immune system 23 | 16,909
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 4 | 4,145
Kinase 4 | 634
Transcription Factor 1 | 1,400

GO Process

positive regulation of focal a... 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Protein phosphatase 1F PPM1F Tbio Enzyme -1.53852 37.0 236
Collagen alpha-1(XVI) chain COL16A1 Tbio Non-IDG -0.91124 6.99 35
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Receptor-type tyrosine-protein phosphatase eta PTPRJ Tbio Enzyme -1.98955 114.2 298
Protein S100-A10 S100A10 Tbio Non-IDG -2.26116 191.4 354
Integrin beta-1-binding protein 1 ITGB1BP1 Tbio Non-IDG -1.23128 20.8 138
Vascular endothelial growth factor receptor 2 KDR Tclin Kinase -3.67555 4544.8 2373
Ras GTPase-activating-like protein IQGAP1 IQGAP1 Tbio Enzyme -2.27732 224.8 291
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297