Development Level

Tbio 25 | 11,445
Tchem 3 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating serum al... 2 | 82
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal retina morphology 1 | 71
abnormal testis morphology 1 | 43
absent pinna reflex 1 | 23
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating magnesiu... 1 | 13
decreased eosinophil cell numb... 1 | 24
decreased mean corpuscular hem... 1 | 50
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112

Disease

Carcinoma 23 | 11,493
ovarian cancer 19 | 8,520
psoriasis 17 | 6,694
glioblastoma 16 | 5,792
medulloblastoma, large-cell 16 | 6,241
Astrocytoma, Pilocytic 13 | 3,081
Cancer 13 | 2,499
ependymoma 13 | 4,679
adult high grade glioma 12 | 3,801
group 3 medulloblastoma 11 | 4,104
lung cancer 11 | 4,740
lung carcinoma 11 | 2,843
osteosarcoma 11 | 7,950
Breast cancer 10 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
invasive ductal carcinoma 10 | 2,951
primitive neuroectodermal tumor 10 | 3,035
interstitial cystitis 9 | 2,312
Kidney cancer 8 | 2,613
pancreatic cancer 8 | 2,398
subependymal giant cell astrocytoma 8 | 2,287
tuberculosis 8 | 2,010
astrocytic glioma 6 | 2,597
astrocytoma 6 | 1,146
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Schizophrenia 5 | 1,160
colon cancer 5 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
juvenile dermatomyositis 5 | 1,187
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
Atopic dermatitis 4 | 952
Pick disease 4 | 1,894
Rheumatoid arthritis 4 | 1,191
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
group 4 medulloblastoma 4 | 1,855
pituitary cancer 4 | 1,972
Acquired flat foot 3 | 72
Bipolar Disorder 3 | 666
Flatfoot 3 | 73
Nonsyndromic deafness 3 | 142
Wiskott-Aldrich syndrome 3 | 30
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
interstitial lung disease 3 | 298
medulloblastoma 3 | 720
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
Acquired metabolic disease 2 | 336
Acquired scoliosis 2 | 281
Aortic Valve Insufficiency 2 | 40
Arachnodactyly 2 | 49
Autistic Disorder 2 | 364
Blue sclera 2 | 32
Byzanthine arch palate 2 | 194
Cardiomegaly 2 | 116
Chemical and Drug Induced Liver Injury 2 | 195
Chest Pain 2 | 38
Chronic Lymphocytic Leukemia 2 | 262
Cleft uvula 2 | 27
Colorectal Neoplasms 2 | 243
Coronary artery disease 2 | 268
Craniosynostosis 2 | 74
Curvature of spine 2 | 282
Deafness 2 | 198
Decreased tendon reflex 2 | 122
Dyspnea, Paroxysmal 2 | 13
Endometriosis 2 | 540
Gout 2 | 106
HIV Infections 2 | 102
Hypersensitivity reaction type II disease 2 | 253
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Loeys-Dietz syndrome 2 | 23
Multiple Sclerosis 2 | 540
Pectus excavatum 2 | 100
Pulmonary Fibrosis 2 | 106
Tall stature 2 | 34
aldosterone-producing adenoma 2 | 665
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
hereditary spastic paraplegia 2 | 318
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109
sarcoidosis 2 | 370

Tissue

Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Blood and immune system 29 | 16,909
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 7 | 4,145
Epigenetic 2 | 242
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

positive regulation of filopod... 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Teneurin-1 TENM1 Tbio Non-IDG -1.81805 61.8 60
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ARAP1 Tbio Non-IDG -0.99923 14.5 99
Rho family-interacting cell polarization regulator 2 RIPOR2 Tbio Non-IDG -0.97707 10.8 109
E3 ubiquitin-protein ligase NEURL1 NEURL1 Tbio Enzyme -1.09204 13.1 165
Dedicator of cytokinesis protein 11 DOCK11 Tdark Non-IDG -1.84321 58.6 35
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Rho-related GTP-binding protein RhoQ RHOQ Tbio Enzyme -1.48059 28.3 111
Serum response factor SRF Tbio Transcription Factor -2.94583 721.8 474
Paralemmin-1 PALM Tbio Non-IDG -1.24016 17.2 62
Phospholipid phosphatase-related protein type 5 PLPPR5 Tdark Enzyme -0.07918 1.14 87