Development Level

Tbio 22 | 10,625
Tchem 3 | 1,890
Tdark 1 | 7,003

IMPC Phenotype

decreased lean body mass 2 | 195
preweaning lethality, incomple... 2 | 260
abnormal embryo size 1 | 112
absent pinna reflex 1 | 21
decreased body weight 1 | 174
decreased caudal vertebrae num... 1 | 49
decreased circulating magnesiu... 1 | 11
decreased circulating serum al... 1 | 79
decreased eosinophil cell numb... 1 | 41
decreased mean corpuscular hem... 1 | 34
decreased total body fat amoun... 1 | 186
hydrops fetalis 1 | 22
increased bone mineral content 1 | 92
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
preweaning lethality, complete... 1 | 633

Disease

psoriasis 17 | 6,685
medulloblastoma, large-cell 14 | 6,234
ovarian cancer 14 | 8,491
glioblastoma 12 | 5,572
Cancer 11 | 2,346
lung cancer 9 | 4,473
pediatric high grade glioma 9 | 2,712
Breast cancer 8 | 3,098
invasive ductal carcinoma 8 | 2,950
lung carcinoma 8 | 2,844
osteosarcoma 8 | 7,933
pilocytic astrocytoma 8 | 3,086
primitive neuroectodermal tumor 8 | 3,031
astrocytoma 7 | 1,493
atypical teratoid / rhabdoid tumor 7 | 4,369
group 4 medulloblastoma 7 | 1,875
interstitial cystitis 7 | 2,299
pancreatic cancer 6 | 2,300
posterior fossa group A ependymoma 6 | 1,511
subependymal giant cell astrocytoma 6 | 2,287
colon cancer 5 | 1,475
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
tuberculosis 5 | 1,563
Atopic dermatitis 4 | 944
Carcinoma 4 | 2,147
adrenocortical carcinoma 4 | 1,427
adult high grade glioma 4 | 2,148
breast carcinoma 4 | 1,614
group 3 medulloblastoma 4 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
juvenile dermatomyositis 4 | 1,189
malignant mesothelioma 4 | 3,163
oligodendroglioma 4 | 2,849
sonic hedgehog group medulloblastoma 4 | 1,482
spina bifida 4 | 1,064
ulcerative colitis 4 | 2,087
Kidney disease 3 | 397
Pick disease 3 | 1,893
Rheumatoid Arthritis 3 | 1,170
active Crohn's disease 3 | 918
active ulcerative colitis 3 | 477
acute quadriplegic myopathy 3 | 1,157
astrocytic glioma 3 | 2,241
interstitial lung disease 3 | 292
lung adenocarcinoma 3 | 2,714
non-small cell lung cancer 3 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
pituitary cancer 3 | 1,972
Acquired metabolic disease 2 | 267
Alzheimer's disease 2 | 644
Autistic Disorder 2 | 320
Cleft palate 2 | 125
Colorectal Neoplasms 2 | 217
Craniosynostosis 2 | 47
Familial thoracic aortic aneurysm and aortic dissection 2 | 13
Hypersensitivity reaction type II disease 2 | 235
Multiple Sclerosis 2 | 498
Pulmonary Fibrosis 2 | 66
Wiskott-Aldrich syndrome 2 | 27
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
chronic lymphocytic leukemia 2 | 244
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,663
pancreatic carcinoma 2 | 567
sarcoidosis 2 | 368
Adult T-Cell Lymphoma/Leukemia 1 | 30
Age related macular degeneration 1 | 84
Amenorrhea 1 | 60
Aortic aneurysm 1 | 34
Arrhythmogenic right ventricular cardiomyopathy 1 | 27
Brachydactyly 1 | 52
Brain disease 1 | 84
Cleft Lip 1 | 91
Common variable immunodeficiency 1 | 98
Congestive heart failure 1 | 36
Craniofacial Abnormalities 1 | 147
Dental caries 1 | 67
Facies 1 | 8
HIV Infections 1 | 99
Hemolytic anemia 1 | 70
Hereditary hemorrhagic telangiectasia 1 | 14
Human immunodeficiency virus infectious disease 1 | 129
Intermediate coronary syndrome 1 | 12
Kidney cancer 1 | 121
Lambert-Eaton myasthenic syndrome 1 | 14
Learning disability 1 | 20
Leukemia, Myelocytic, Acute 1 | 113
Macular degeneration 1 | 44
Migraine Disorders 1 | 26
Myasthenia Gravis 1 | 26
Osteoarthritis 1 | 96
Ovarian dysfunction 1 | 19
Premature ovarian failure 1 | 64
Premature ovarian failure 1 1 | 2
Vaccinia 1 | 37

Tissue

Cardiovascular System 26 | 17,957
Digestive Tract 26 | 18,472
Endocrine System 26 | 18,511
Female tissues 26 | 18,646
Liver and Pancreas 26 | 18,135
Male tissues 26 | 17,968
Nervous System 26 | 18,560
Respiratory system 26 | 17,483
Skin and soft tissues 26 | 18,114
Urinary Tract 26 | 18,443
Blood and immune system 25 | 17,994

Target Family

Non-IDG 15 | 11,969
Enzyme 6 | 4,146
Epigenetic 2 | 242
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

positive regulation of filopod... 26 | 26
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynamin-3 DNM3 Tbio Non-IDG -1.39919 21.9 126
Protein kinase C-binding protein 1 ZMYND8 Tbio Epigenetic -1.02938 10.6 124
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.92178 654.5 340
Phospholipid phosphatase-related protein type 5 PLPPR5 Tdark Enzyme -0.07918 1.14 77
Ras-related protein Ral-A RALA Tbio Enzyme -2.19700 159.2 185
Breast carcinoma-amplified sequence 3 BCAS3 Tbio Non-IDG -1.20143 15.1 133
C-C chemokine receptor type 7 CCR7 Tchem GPCR -2.97056 928.0 549
Transforming growth factor beta-3 TGFB3 Tchem Non-IDG -3.01218 852.5 285
Formin-binding protein 1-like FNBP1L Tbio Non-IDG -1.53747 32.4 133
Serum response factor SRF Tbio Transcription Factor -2.93246 688.5 447