Development Level

Tbio 29 | 11,445
Tchem 16 | 1,598
Tclin 7 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
enlarged heart 3 | 210
increased circulating choleste... 3 | 66
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal seminal vesicle morph... 2 | 114
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
edema 2 | 59
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
microphthalmia 2 | 26
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
cataract 1 | 92
corneal opacity 1 | 32
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
female infertility 1 | 60
fused cornea and lens 1 | 5
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased circulating total pr... 1 | 28
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
male infertility 1 | 123
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4

Disease

Cancer 40 | 2,499
Carcinoma 33 | 11,493
ovarian cancer 33 | 8,520
osteosarcoma 32 | 7,950
glioblastoma 31 | 5,792
psoriasis 31 | 6,694
lung cancer 30 | 4,740
medulloblastoma, large-cell 26 | 6,241
Breast cancer 25 | 3,578
atypical teratoid / rhabdoid tumor 24 | 5,112
malignant mesothelioma 23 | 3,232
pancreatic cancer 23 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
lung carcinoma 20 | 2,843
ependymoma 19 | 4,679
invasive ductal carcinoma 19 | 2,951
group 3 medulloblastoma 18 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
adrenocortical carcinoma 17 | 1,428
Astrocytoma, Pilocytic 16 | 3,081
breast carcinoma 16 | 1,638
astrocytic glioma 15 | 2,597
lung adenocarcinoma 15 | 2,716
non-small cell lung cancer 15 | 2,890
adult high grade glioma 14 | 3,801
interstitial cystitis 14 | 2,312
oligodendroglioma 14 | 2,850
Atopic dermatitis 13 | 952
cystic fibrosis 13 | 1,696
ductal carcinoma in situ 13 | 1,745
pituitary cancer 13 | 1,972
tuberculosis 13 | 2,010
Liver Cirrhosis, Experimental 12 | 769
ulcerative colitis 12 | 1,819
Prostatic Neoplasms 11 | 495
Schizophrenia 11 | 1,160
acute quadriplegic myopathy 11 | 1,158
primary pancreatic ductal adenocarcinoma 11 | 1,109
primitive neuroectodermal tumor 11 | 3,035
Atherosclerosis 10 | 291
Autosomal recessive predisposition 10 | 1,442
Breast Neoplasms 10 | 445
Kidney cancer 10 | 2,613
Lung Neoplasms 10 | 232
Mammary Neoplasms 10 | 425
Mammary Neoplasms, Experimental 10 | 154
colon cancer 10 | 1,478
diabetes mellitus 10 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Animal Mammary Neoplasms 9 | 136
Duchenne muscular dystrophy 9 | 601
Endometriosis 9 | 540
Kidney disease 9 | 430
Mammary Neoplasms, Animal 9 | 136
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
subependymal giant cell astrocytoma 9 | 2,287
Carcinoma, Hepatocellular 8 | 228
Coronary artery disease 8 | 268
Hypertension 8 | 396
Hypertensive disease 8 | 292
Liver carcinoma 8 | 240
Small head 8 | 374
acute myeloid leukemia 8 | 783
astrocytoma 8 | 1,146
nasopharyngeal carcinoma 8 | 1,058
Bipolar Disorder 7 | 666
Cognitive delay 7 | 608
Depressive disorder 7 | 409
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
gastric carcinoma 7 | 807
juvenile dermatomyositis 7 | 1,187
limb girdle muscular dystrophy 2A 7 | 213
medulloblastoma 7 | 720
pediatric high grade glioma 7 | 1,064
urothelial carcinoma 7 | 318
Alzheimer's disease 6 | 658
Cell Transformation, Neoplastic 6 | 97
Cleft Palate 6 | 271
Delayed bone age 6 | 136
Fetal Growth Retardation 6 | 189
Hypoplastic mandible condyle 6 | 275
Intellectual disability 6 | 1,016
Lung disease 6 | 142
Mandibular hypoplasia 6 | 275
Mesothelioma, Malignant 6 | 105
Micrognathism 6 | 275
Neoplasm Invasiveness 6 | 161
Neoplasm Metastasis 6 | 168
Neoplastic Cell Transformation 6 | 89
Pulmonary Fibrosis 6 | 106
Rheumatoid arthritis 6 | 1,191
Stomach Neoplasms 6 | 300
cutaneous lupus erythematosus 6 | 1,057
Dull intelligence 5 | 645
Intrauterine retardation 5 | 176
Poor school performance 5 | 645
Vascular disease 5 | 319
spina bifida 5 | 1,074

Tissue

Blood and immune system 52 | 16,909
Digestive Tract 52 | 17,369
Endocrine System 52 | 18,159
Nervous System 52 | 16,725
Urinary Tract 52 | 16,678
Female tissues 51 | 17,400
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Respiratory system 51 | 16,393
Skin and soft tissues 51 | 17,230
Cardiovascular System 50 | 15,192

Target Family

Non-IDG 29 | 12,091
Kinase 8 | 634
Enzyme 7 | 4,145
Transcription Factor 5 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

GO Process

positive regulation of fibrobl... 52 | 52
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Urotensin-2 receptor UTS2R Tchem GPCR -1.95094 62.5 182
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 Tclin Enzyme -2.97252 871.7 197
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Ribonuclease H2 subunit B RNASEH2B Tbio Enzyme -1.44354 27.2 128
Zinc finger MIZ domain-containing protein 1 ZMIZ1 Tbio Transcription Factor -1.57174 37.9 126
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
CST complex subunit CTC1 CTC1 Tbio Non-IDG -1.74818 54.2 49
DNA ligase 4 LIG4 Tbio Enzyme -2.14909 140.9 204
Discoidin domain-containing receptor 2 DDR2 Tchem Kinase -2.12297 152.1 302