Development Level

Tchem 7 | 1,388
Tbio 5 | 11,651

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
decreased bone mineral content 1 | 151
decreased circulating insulin ... 1 | 76
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
enlarged heart 1 | 210
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating calcium ... 1 | 34
increased circulating triglyce... 1 | 42
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

glioblastoma 11 | 5,792
Carcinoma 10 | 11,493
atypical teratoid / rhabdoid tumor 10 | 5,112
adult high grade glioma 9 | 3,801
astrocytic glioma 9 | 2,597
ependymoma 9 | 4,679
osteosarcoma 9 | 7,950
Astrocytoma, Pilocytic 8 | 3,081
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
oligodendroglioma 7 | 2,850
psoriasis 7 | 6,694
tuberculosis 7 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pancreatic cancer 6 | 2,398
Cancer 5 | 2,499
Kidney cancer 5 | 2,613
cystic fibrosis 5 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
primitive neuroectodermal tumor 5 | 3,035
Kidney disease 4 | 430
Pick disease 4 | 1,894
Renal Cell Carcinoma 4 | 214
diabetes mellitus 4 | 1,728
malignant mesothelioma 4 | 3,232
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
Acquired scoliosis 3 | 281
Asthma 3 | 385
Breast Neoplasms 3 | 445
Breast cancer 3 | 3,578
Byzanthine arch palate 3 | 194
Colorectal Neoplasms 3 | 243
Curvature of spine 3 | 282
Fibrosis 3 | 44
Heart disease 3 | 306
Hypertension 3 | 396
Intellectual disability 3 | 1,016
Mammary Neoplasms 3 | 425
Schizophrenia 3 | 1,160
Seizures 3 | 596
colon cancer 3 | 1,478
hepatocellular carcinoma 3 | 547
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 1,819
Arthritis 2 | 290
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Concave bridge of nose 2 | 195
Coronary artery disease 2 | 268
Deafness 2 | 198
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Depressive disorder 2 | 409
Epilepsy 2 | 792
Exophthalmos 2 | 112
Heart conduction disease 2 | 83
Hyperplasia 2 | 27
Hypersensitivity reaction type II disease 2 | 253
Inflammation 2 | 120
Inflammatory bowel disease 2 | 151
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Liver Cirrhosis 2 | 181
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Macrotia 2 | 87
Mood Disorders 2 | 184
Myocardial Ischemia 2 | 169
Myopathy 2 | 185
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Pectus excavatum 2 | 100
Prominent eyes 2 | 96
Prominent globes 2 | 96
Prostatic Neoplasms 2 | 495
Proteinuria 2 | 144
Protruding eyes 2 | 96
Psychotic Disorders 2 | 151
Short nose 2 | 132
Small nose 2 | 132
Vascular disease 2 | 319
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
gastric carcinoma 2 | 807
head and neck cancer 2 | 271
lung adenocarcinoma 2 | 2,716
mucosa-associated lymphoid tissue lymphoma 2 | 484

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 6 | 12,091
Kinase 5 | 634
Transporter 1 | 473

GO Process

positive regulation of fibrobl... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Dematin DMTN Tbio Non-IDG -1.73686 56.6 158
Sodium/calcium exchanger 1 SLC8A1 Tchem Transporter -2.52990 349.1 141
Discoidin domain-containing receptor 2 DDR2 Tchem Kinase -2.12297 152.1 302
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.36734 20160.1 3565
Rho guanine nucleotide exchange factor 7 ARHGEF7 Tbio Non-IDG -2.18033 152.8 183
BAG family molecular chaperone regulator 4 BAG4 Tbio Non-IDG -1.37421 26.6 311
Serine/threonine-protein kinase PAK 3 PAK3 Tchem Kinase -1.35059 21.1 377