Development Level

Tchem 6 | 1,890
Tbio 5 | 10,625

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal heart morphology 1 | 51
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
decreased body length 1 | 108
decreased circulating insulin ... 1 | 75
enlarged heart 1 | 111
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
preweaning lethality, complete... 1 | 633

Disease

glioblastoma 9 | 5,572
atypical teratoid / rhabdoid tumor 8 | 4,369
osteosarcoma 8 | 7,933
medulloblastoma, large-cell 7 | 6,234
ovarian cancer 7 | 8,492
pilocytic astrocytoma 7 | 3,086
psoriasis 7 | 6,685
ependymoma 6 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
oligodendroglioma 6 | 2,849
tuberculosis 6 | 1,563
astrocytic glioma 5 | 2,241
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
pancreatic cancer 5 | 2,300
pediatric high grade glioma 5 | 2,712
Cancer 4 | 2,346
Carcinoma 4 | 2,147
Kidney disease 4 | 397
cystic fibrosis 4 | 1,670
diabetes mellitus 4 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
lung carcinoma 4 | 2,844
medulloblastoma 4 | 1,524
primary pancreatic ductal adenocarcinoma 4 | 1,271
primitive neuroectodermal tumor 4 | 3,031
Breast cancer 3 | 3,099
Colorectal Neoplasms 3 | 217
Diabetic Retinopathy 3 | 53
Fibrosis 3 | 40
Heart disease 3 | 279
Hypertension 3 | 293
Obesity 3 | 616
Pick disease 3 | 1,893
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
colon cancer 3 | 1,475
group 3 medulloblastoma 3 | 2,254
hepatocellular carcinoma 3 | 550
invasive ductal carcinoma 3 | 2,950
malignant mesothelioma 3 | 3,163
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 2,087
Adenoma 2 | 165
Alzheimer's disease 2 | 644
Arthritis 2 | 248
Asthma 2 | 349
Atherosclerosis 2 | 275
Atopic dermatitis 2 | 944
Cardiomyopathies 2 | 90
Colorectal Cancer 2 | 62
Coronary artery disease 2 | 240
Diabetes Mellitus, Experimental 2 | 106
Diabetic Nephropathy 2 | 37
Gastrointestinal stromal tumor 2 | 61
Hyperglycemia 2 | 120
Hyperplasia 2 | 26
Hypertensive disease 2 | 193
Inflammation 2 | 109
Inflammatory bowel disease 2 | 142
Intellectual disability 2 | 573
Liver Cirrhosis 2 | 101
Liver disease 2 | 219
Lung Neoplasms 2 | 171
Lung disease 2 | 136
Mammary Neoplasms 2 | 410
Myocardial Infarction 2 | 126
Myocardial Ischemia 2 | 169
Myopathy 2 | 128
Osteoporosis 2 | 259
Peripheral vascular disease 2 | 90
Portal hypertension 2 | 21
Prostatic Neoplasms 2 | 471
Renal Cell Carcinoma 2 | 199
Schizophrenia 2 | 503
Skin Neoplasms 2 | 49
Squamous cell carcinoma 2 | 96
Vascular disease 2 | 281
adrenocortical carcinoma 2 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
gastric carcinoma 2 | 832
head and neck cancer 2 | 270
lung adenocarcinoma 2 | 2,714
lung cancer 2 | 4,473
mucosa-associated lymphoid tissue lymphoma 2 | 480
non-small cell lung cancer 2 | 2,798
Adenocarcinoma 1 | 115
Aortic aneurysm 1 | 34
Aortic valve insufficiency 1 | 22
Calcinosis 1 | 63
Cardiomegaly 1 | 66
Colon Carcinoma 1 | 25
Familial adenomatous polyposis 1 | 33
Human immunodeficiency virus infectious disease 1 | 129
Meningioma 1 | 27
Neoplasm Invasiveness 1 | 127
Pancreatitis 1 | 97
Periodontal disease 1 | 37
Pulmonary emphysema 1 | 34
Skin disease 1 | 65

Tissue

Blood and immune system 11 | 17,995
Cardiovascular System 11 | 17,958
Digestive Tract 11 | 18,473
Endocrine System 11 | 18,512
Female tissues 11 | 18,647
Liver and Pancreas 11 | 18,136
Male tissues 11 | 17,969
Nervous System 11 | 18,561
Respiratory system 11 | 17,484
Skin and soft tissues 11 | 18,115
Urinary Tract 11 | 18,444

Target Family

Non-IDG 6 | 11,969
Kinase 4 | 634
Transporter 1 | 473

GO Process

positive regulation of fibrobl... 11 | 11
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.82684 20956.6 961
Dematin DMTN Tbio Non-IDG -1.71236 54.9 140
Serine/threonine-protein kinase PAK 3 PAK3 Tchem Kinase -1.33193 20.3 334
Protein kinase C epsilon type PRKCE Tchem Kinase -1.38686 21.9 345
Sodium/calcium exchanger 1 SLC8A1 Tchem Transporter -2.51097 236.4 122
Discoidin domain-containing receptor 2 DDR2 Tchem Kinase -2.07828 137.3 254
Rho guanine nucleotide exchange factor 7 ARHGEF7 Tbio Non-IDG -2.13575 139.1 160
RAC-alpha serine/threonine-protein kinase AKT1 Tchem Kinase -4.32386 18275.3 3137
Urotensin-2 UTS2 Tbio Non-IDG -2.53120 395.9 163
Thrombospondin-1 THBS1 Tbio Non-IDG -3.04674 1192.7 409