Development Level

Tbio 5 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal glucose homeostasis 1 | 4
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased large unstained cell... 1 | 11
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
thrombocytosis 1 | 27

Disease

Carcinoma 7 | 11,493
Obesity 7 | 678
Fatty liver disease 6 | 103
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
invasive ductal carcinoma 6 | 2,951
ovarian cancer 6 | 8,520
Cancer 5 | 2,499
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
group 3 medulloblastoma 5 | 4,104
psoriasis 5 | 6,694
Diabetes Mellitus, Experimental 4 | 108
Insulin Resistance 4 | 72
breast carcinoma 4 | 1,638
osteosarcoma 4 | 7,950
Breast cancer 3 | 3,578
Diabetes Mellitus, Noninsulin-Dependent 3 | 31
Hepatomegaly 3 | 285
Hyperglycemia 3 | 137
Hyperinsulinism 3 | 133
Kidney Failure, Chronic 3 | 46
Kidney cancer 3 | 2,613
Lipid metabolism disorder 3 | 114
Polycystic ovary syndrome 3 | 360
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Acute Kidney Tubular Necrosis 2 | 6
Autosomal recessive predisposition 2 | 1,442
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Cardiomegaly 2 | 116
Coronary artery disease 2 | 268
Epilepsy 2 | 792
Heart disease 2 | 306
Hyperlipidemia 2 | 43
Hyperlipidemias 2 | 17
Hypertension 2 | 396
Hypoglycemia 2 | 152
Kidney Tubular Necrosis, Acute 2 | 4
Liver carcinoma 2 | 240
Mammary Neoplasms 2 | 425
Prostatic Neoplasms 2 | 495
Seizures 2 | 596
Steatohepatitis 2 | 44
Stomach Neoplasms 2 | 300
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
fibroadenoma 2 | 559
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Acanthosis Nigricans 1 | 27
Autosomal recessive Robinow syndrome 1 | 27
Bunion 1 | 26
Cell Transformation, Neoplastic 1 | 97
Convex nasal bridge 1 | 57
Convex nasal ridge 1 | 37
Dyslipidemias 1 | 27
Facial asymmetry 1 | 32
Familial partial lipodystrophy 1 | 12
Flat forehead 1 | 5
Gynecomastia 1 | 64
Hallux Valgus 1 | 26
Hemiplegia and hemiparesis 1 | 38
Hypertriglyceridemia 1 | 17
Hypertriglyceridemia result 1 | 37
Intestinal volvulus 1 | 8
Large for gestational age 1 | 11
Lipidoses 1 | 19
Lipodystrophy 1 | 40
Lipoidosis 1 | 19
Lordosis 1 | 54
Myocardial Reperfusion Injury 1 | 37
Narrow nose 1 | 20
Narrow palate 1 | 20
Neoplasms 1 | 63
Neoplastic Cell Transformation 1 | 89
Obesity, Abdominal 1 | 24
Oligomenorrhea 1 | 16
Open Bite 1 | 21
Plagiocephaly 1 | 20
Plagiocephaly, Nonsynostotic 1 | 20
Precancerous Conditions 1 | 80
Primary Prevention of Coronary Heart Disease 1 | 4
Prominent nasal bridge 1 | 57
Saethre-Chotzen syndrome 1 | 7
Shallow orbits 1 | 13

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 4 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Process

positive regulation of fatty a... 9 | 9
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin receptor substrate 2 IRS2 Tbio Non-IDG -2.64133 414.7 227
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.38489 225.0 306
Peroxisome proliferator-activated receptor alpha PPARA Tclin Nuclear Receptor -3.37176 2457.9 501
Twist-related protein 1 TWIST1 Tbio Transcription Factor -3.91883 8025.6 425
RAC-beta serine/threonine-protein kinase AKT2 Tchem Kinase -2.60567 332.5 1173
Insulin receptor substrate 1 IRS1 Tbio Non-IDG -3.18611 1482.3 1920
Fatty acid-binding protein, liver FABP1 Tchem Non-IDG -2.57840 448.8 411
Perilipin-5 PLIN5 Tbio Non-IDG -1.72412 60.3 92
ATP-binding cassette sub-family D member 2 ABCD2 Tbio Transporter -1.65079 43.1 185