Development Level

Tbio 10 | 10,625
Tchem 4 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal bone mineralization 1 | 55
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating insulin ... 1 | 75
decreased lactate dehydrogenas... 1 | 14
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
increased body weight 1 | 42
increased bone mineral content 1 | 92
preweaning lethality, complete... 1 | 633
small superior vagus ganglion 1 | 20

Disease

ovarian cancer 11 | 8,492
glioblastoma 9 | 5,572
psoriasis 9 | 6,685
osteosarcoma 8 | 7,933
Cancer 7 | 2,346
medulloblastoma, large-cell 7 | 6,234
pancreatic cancer 7 | 2,300
atypical teratoid / rhabdoid tumor 6 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
lung cancer 6 | 4,473
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
invasive ductal carcinoma 5 | 2,950
lung carcinoma 5 | 2,844
malignant mesothelioma 5 | 3,163
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
Breast cancer 4 | 3,099
Pick disease 4 | 1,893
astrocytic glioma 4 | 2,241
colon cancer 4 | 1,475
cystic fibrosis 4 | 1,670
gastric carcinoma 4 | 832
group 3 medulloblastoma 4 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
nasopharyngeal carcinoma 4 | 1,056
ulcerative colitis 4 | 2,087
Mammary Neoplasms 3 | 410
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
ependymoma 3 | 2,514
interstitial cystitis 3 | 2,299
lung adenocarcinoma 3 | 2,714
non-small cell lung cancer 3 | 2,798
oligodendroglioma 3 | 2,849
primitive neuroectodermal tumor 3 | 3,031
Adenoma 2 | 165
Attention deficit hyperactivity disorder 2 | 156
Carcinoma 2 | 2,147
Craniofacial Abnormalities 2 | 147
Down syndrome 2 | 548
Renal Cell Carcinoma 2 | 199
X-linked cerebral adrenoleukodystrophy 2 | 115
active Crohn's disease 2 | 918
adrenocortical carcinoma 2 | 1,427
breast carcinoma 2 | 1,614
chronic rhinosinusitis 2 | 512
diabetes mellitus 2 | 1,663
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
head and neck cancer 2 | 270
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
hepatocellular carcinoma 2 | 550
medulloblastoma 2 | 1,524
pancreatic carcinoma 2 | 567
pediatric high grade glioma 2 | 2,712
pilocytic astrocytoma 2 | 3,086
sonic hedgehog group medulloblastoma 2 | 1,482
spina bifida 2 | 1,064
tuberculosis 2 | 1,563
Acromesomelic dysplasia 1 | 10
Brachydactyly 1 | 52
Cerebral artery occlusion 1 | 3
Colorectal Cancer 1 | 62
Common variable immunodeficiency 1 | 98
DOID:2627 1 | 14
Diabetic Retinopathy 1 | 53
Disease of mental health 1 | 22
Fibroid Tumor 1 | 6
Fibrosarcoma 1 | 12
Fibrosis 1 | 40
Fucosidosis 1 | 10
Gastrointestinal stromal tumor 1 | 61
Glioma 1 | 66
Hamman-Rich syndrome 1 | 35
Head and Neck Neoplasms 1 | 23
Hemangioma 1 | 35
Immune system cancer 1 | 38
Juvenile Myelomonocytic Leukemia 1 | 21
Kidney cancer 1 | 121
Learning disability 1 | 20
Leukemia, Myelocytic, Acute 1 | 113
Liposarcoma 1 | 20
Liver Cirrhosis 1 | 101
Melanoma 1 | 261
Neoplastic Syndromes, Hereditary 1 | 48
Neurilemmoma 1 | 20
Neurofibromatosis 1 | 37
Osteochondrosis 1 | 14
Pancreatic Neuroendocrine Tumor 1 | 45
Persistent generalized lymphadenopathy 1 | 15
Phaeochromocytoma 1 | 20
Pheochromocytoma 1 | 22
Poikiloderma with neutropenia 1 | 5
Primary immunodeficiency disease 1 | 52
Pulmonary Fibrosis 1 | 66
Sarcoma 1 | 49
Scoliosis 1 | 40
Squamous cell carcinoma 1 | 96
Syndactyly 1 | 56
sarcoidosis 1 | 368

Tissue

Cardiovascular System 14 | 17,958
Digestive Tract 14 | 18,473
Endocrine System 14 | 18,512
Female tissues 14 | 18,647
Nervous System 14 | 18,561
Skin and soft tissues 14 | 18,115
Urinary Tract 14 | 18,444
Blood and immune system 13 | 17,995
Liver and Pancreas 13 | 18,136
Male tissues 13 | 17,969
Respiratory system 13 | 17,484

Target Family

Non-IDG 10 | 11,969
Kinase 3 | 634
Enzyme 1 | 4,146

GO Process

positive regulation of extrins... 14 | 14
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.69176 51.3 183
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.67624 440.9 327
E3 ubiquitin-protein ligase ZSWIM2 ZSWIM2 Tbio Enzyme -2.24877 171.7 87
Astrocytic phosphoprotein PEA-15 PEA15 Tbio Non-IDG -1.92682 101.0 321
Ski-like protein SKIL Tbio Non-IDG -2.15950 140.8 225
Myelin and lymphocyte protein MAL Tbio Non-IDG -1.37645 21.5 151
Neurofibromin NF1 Tbio Non-IDG -3.57517 3833.1 331
Secreted frizzled-related protein 1 SFRP1 Tchem Non-IDG -2.37301 259.7 230
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -1.95873 74.2 409
p53-induced death domain-containing protein 1 PIDD1 Tbio Non-IDG -1.96396 92.0 75