Development Level

Tbio 10 | 11,651
Tchem 4 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating insulin ... 1 | 76
decreased lactate dehydrogenas... 1 | 16
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased circulating glucose ... 1 | 24
small superior vagus ganglion 1 | 74

Disease

ovarian cancer 11 | 8,520
Carcinoma 10 | 11,493
glioblastoma 9 | 5,792
psoriasis 9 | 6,694
osteosarcoma 8 | 7,950
Cancer 7 | 2,499
atypical teratoid / rhabdoid tumor 7 | 5,112
medulloblastoma, large-cell 7 | 6,241
pancreatic cancer 7 | 2,398
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung cancer 6 | 4,740
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Breast cancer 4 | 3,578
Pick disease 4 | 1,894
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
nasopharyngeal carcinoma 4 | 1,058
primary pancreatic ductal adenocarcinoma 4 | 1,109
ulcerative colitis 4 | 1,819
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Mammary Neoplasms 3 | 425
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
Adenoma 2 | 167
Astrocytoma, Pilocytic 2 | 3,081
Attention deficit hyperactivity disorder 2 | 278
Bipolar Disorder 2 | 666
Craniofacial Abnormalities 2 | 151
Down syndrome 2 | 499
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Renal Cell Carcinoma 2 | 214
Sarcoma 2 | 62
Schizophrenia 2 | 1,160
Short stature 2 | 531
Skin cancer 2 | 469
X-linked cerebral adrenoleukodystrophy 2 | 116
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
head and neck cancer 2 | 271
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
Abnormality of the hip bone 1 | 16
Abnormality of the thorax 1 | 19
Abnormality of the tibia 1 | 9
Amyotrophic lateral sclerosis type 14 1 | 2
Autoimmune lymphoproliferative syndrome 1 | 11
Axillary freckling 1 | 5
Bone Diseases, Developmental 1 | 27
Broad hallux 1 | 29
Cone-shaped epiphyses 1 | 24
Fibrodysplasia ossificans progressiva 1 | 17
Gingival recession 1 | 13
Hearing Loss, Sensorineural 1 | 11
Hypoplastic finger 1 | 17
Juvenile xanthogranuloma 1 | 7
Learning Disorders 1 | 29
Moyamoya disease 1 | 10
NGLY1-deficiency 1 | 4
Nephritis, Interstitial 1 | 10
Neurofibromatoses 1 | 5
Optic nerve glioma 1 | 4
Paraparesis 1 | 6
Parathyroid Adenoma 1 | 19
Piebaldism 1 | 15
Primary immunodeficiency disease 1 | 54
Recurrent fungal infections 1 | 13
Recurrent viral infections 1 | 15
Short femoral neck 1 | 15
Short finger 1 | 17
Short middle phalanx of the 5th finger 1 | 13
Short phalanx of finger 1 | 32
Thrombotic thrombocytopenic purpura 1 | 14
Tuberous sclerosis 1 | 19

Tissue

Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Nervous System 14 | 16,725
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 10 | 12,091
Kinase 3 | 634
Enzyme 1 | 4,145

GO Process

positive regulation of extrins... 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
E3 ubiquitin-protein ligase ZSWIM2 ZSWIM2 Tbio Enzyme -2.28388 186.1 92
Ski-like protein SKIL Tbio Non-IDG -2.19816 173.0 352
Secreted frizzled-related protein 1 SFRP1 Tchem Non-IDG -2.40092 279.5 264
Astrocytic phosphoprotein PEA-15 PEA15 Tbio Non-IDG -1.95527 108.9 355
Myelin and lymphocyte protein MAL Tbio Non-IDG -1.38710 22.0 164
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.71858 56.5 209
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Bone morphogenetic protein receptor type-1B BMPR1B Tchem Kinase -2.00303 86.8 498