Development Level

Tchem 3 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

decreased blood urea nitrogen ... 1 | 51
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

Cancer 5 | 2,499
ovarian cancer 5 | 8,520
Acquired scoliosis 4 | 281
Carcinoma 4 | 11,493
Curvature of spine 4 | 282
glioblastoma 4 | 5,792
osteosarcoma 4 | 7,950
Abnormality of the iris 3 | 14
Acquired flat foot 3 | 72
Aortic Valve Insufficiency 3 | 40
Aortic aneurysm 3 | 38
Aortic aneurysm, familial thoracic 3 3 | 13
Arachnodactyly 3 | 49
Arterial tortuosity 3 | 5
Ascending aortic dissection 3 | 13
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Byzanthine arch palate 3 | 194
Cardiomegaly 3 | 116
Chest Pain 3 | 38
Cleft Palate 3 | 271
Coronary artery disease 3 | 268
Cutis marmorata 3 | 32
Cystic medial necrosis of aorta 3 | 13
Descending aortic dissection 3 | 13
Dissection of aorta 3 | 9
Dyspnea on exertion 3 | 24
Dyspnea, Paroxysmal 3 | 13
Familial thoracic aortic aneurysm and aortic dissection 3 | 13
Flatfoot 3 | 73
Hypertensive disease 3 | 292
Impaired left ventricular function 3 | 16
Increase in blood pressure 3 | 119
Left-Sided Heart Failure 3 | 16
Loeys-Dietz Aortic Aneurysm Syndrome 3 | 13
Loeys-Dietz syndrome 3 | 23
Tall stature 3 | 34
Thoracic aortic aneurysm 3 | 15
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
Aneurysm, Dissecting 2 | 8
Aortic Aneurysm, Thoracic 2 | 8
Atypical scarring of skin 2 | 62
Blue sclera 2 | 32
COPD 2 | 118
Cleft palate with cleft lip 2 | 23
Cleft uvula 2 | 27
Connective tissue disease 2 | 62
Craniofacial Abnormalities 2 | 151
Craniosynostosis 2 | 74
Cyanosis 2 | 17
Epilepsy 2 | 792
Eye Abnormalities 2 | 35
Flexion contracture of proximal interphalangeal joint 2 | 75
Gaucher disease type 1 2 | 180
Hereditary hemorrhagic telangiectasia 2 | 13
Hernia, Inguinal 2 | 89
Hypoplastic mandible condyle 2 | 275
Hypotrophic malar bone 2 | 129
Intermittent migraine headaches 2 | 68
Linear atrophy 2 | 15
Liver Cirrhosis 2 | 181
Malar flattening 2 | 129
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Migraine Disorders 2 | 76
Oral cleft 2 | 18
Orbital separation excessive 2 | 244
Patent ductus arteriosus 2 | 90
Retrognathia 2 | 54
Seizures 2 | 596
Skull malformation 2 | 38
Sternal anomalies 2 | 19
Ureteral obstruction 2 | 33
Uterine Rupture 2 | 2
active ulcerative colitis 2 | 764
adult high grade glioma 2 | 3,801
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
psoriasis 2 | 6,694
ulcerative colitis 2 | 1,819
Arterial tortuosity syndrome 1 | 7
Arterial tortuosity, generalized 1 | 2
Bunion 1 | 26
Diabetic Nephropathy 1 | 34
Fractures, Bone 1 | 13
Malignant Squamous Cell Neoplasm 1 | 17
Pulmonary Fibrosis 1 | 106
Pulmonary artery aneurysm 1 | 2

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Kinase 3 | 634
Non-IDG 2 | 12,091

GO Process

positive regulation of epithel... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413
Activin receptor type-1 ACVR1 Tchem Kinase -2.47071 290.9 428