Development Level

Tbio 29 | 11,445
Tchem 9 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased circulating glycerol... 2 | 16
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal head morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal limb morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
microphthalmia 1 | 26
polydactyly 1 | 7
preweaning lethality, incomple... 1 | 499
protruding tongue 1 | 3

Disease

Carcinoma 32 | 11,493
Cancer 29 | 2,499
ovarian cancer 29 | 8,520
lung cancer 26 | 4,740
Breast cancer 22 | 3,578
ependymoma 22 | 4,679
glioblastoma 22 | 5,792
psoriasis 20 | 6,694
Astrocytoma, Pilocytic 19 | 3,081
osteosarcoma 19 | 7,950
atypical teratoid / rhabdoid tumor 18 | 5,112
interstitial cystitis 18 | 2,312
malignant mesothelioma 18 | 3,232
pancreatic cancer 17 | 2,398
medulloblastoma, large-cell 16 | 6,241
adult high grade glioma 15 | 3,801
group 3 medulloblastoma 15 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 15 | 2,951
cystic fibrosis 14 | 1,696
lung carcinoma 14 | 2,843
non-small cell lung cancer 14 | 2,890
Kidney cancer 13 | 2,613
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 12 | 3,035
Orbital separation excessive 11 | 244
Osteoarthritis 11 | 184
breast carcinoma 11 | 1,638
diabetes mellitus 11 | 1,728
Cleft Palate 10 | 271
Hypertensive disease 10 | 292
cutaneous lupus erythematosus 10 | 1,057
oligodendroglioma 10 | 2,850
pituitary cancer 10 | 1,972
subependymal giant cell astrocytoma 10 | 2,287
Kidney disease 9 | 430
gastric carcinoma 9 | 807
ulcerative colitis 9 | 1,819
Breast Neoplasms 8 | 445
Craniofacial Abnormalities 8 | 151
Hypotrophic malar bone 8 | 129
Liver Cirrhosis, Experimental 8 | 769
Malar flattening 8 | 129
Pulmonary Fibrosis 8 | 106
Stomach Neoplasms 8 | 300
colon cancer 8 | 1,478
dermatomyositis 8 | 966
tuberculosis 8 | 2,010
Acquired scoliosis 7 | 281
Aortic Valve Insufficiency 7 | 40
Cardiomegaly 7 | 116
Coronary artery disease 7 | 268
Curvature of spine 7 | 282
Hernia, Inguinal 7 | 89
Hypertension 7 | 396
Liver Cirrhosis 7 | 181
Mammary Neoplasms 7 | 425
Osteoporosis 7 | 363
Prostatic Neoplasms 7 | 495
Schizophrenia 7 | 1,160
Ureteral obstruction 7 | 33
active ulcerative colitis 7 | 764
acute quadriplegic myopathy 7 | 1,158
astrocytic glioma 7 | 2,597
group 4 medulloblastoma 7 | 1,855
Acquired flat foot 6 | 72
Alzheimer's disease 6 | 658
Brachydactyly 6 | 156
Colonic Neoplasms 6 | 142
Colorectal Neoplasms 6 | 243
Craniosynostosis 6 | 74
Cutis marmorata 6 | 32
Duchenne muscular dystrophy 6 | 601
Exophthalmos 6 | 112
Flatfoot 6 | 73
Heart disease 6 | 306
Hypoplastic mandible condyle 6 | 275
Increase in blood pressure 6 | 119
Liver disease 6 | 237
Loeys-Dietz syndrome 6 | 23
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Neoplasm Invasiveness 6 | 161
Neoplasm Metastasis 6 | 168
Pick disease 6 | 1,894
Prominent eyes 6 | 96
Prominent globes 6 | 96
Protruding eyes 6 | 96
Short stature 6 | 531
Vascular disease 6 | 319
astrocytoma 6 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
urothelial carcinoma 6 | 318
primary pancreatic ductal adenocarcinoma 5 | 1,109

Tissue

Endocrine System 40 | 18,159
Female tissues 40 | 17,400
Male tissues 40 | 17,142
Skin and soft tissues 40 | 17,230
Urinary Tract 40 | 16,678
Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Cardiovascular System 38 | 15,192
Liver and Pancreas 38 | 16,750
Nervous System 38 | 16,725
Respiratory system 38 | 16,393

Target Family

Non-IDG 26 | 12,091
Transcription Factor 9 | 1,400
Kinase 3 | 634
Epigenetic 2 | 242
Enzyme 1 | 4,145

GO Process

positive regulation of epithel... 41 | 41
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Insulin gene enhancer protein ISL-1 ISL1 Tbio Transcription Factor -2.63352 410.3 382
Forkhead box protein C1 FOXC1 Tbio Transcription Factor -2.28586 201.8 314
Transforming growth factor beta-1-induced transcript 1 protein TGFB1I1 Tbio Non-IDG -1.82580 89.7 147
Golgi-associated plant pathogenesis-related protein 1 GLIPR2 Tbio Non-IDG -0.85891 11.0 109
Protein crumbs homolog 2 CRB2 Tbio Non-IDG -1.44852 30.9 92
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Zinc finger protein 703 ZNF703 Tbio Non-IDG -1.21377 18.7 190
Transforming growth factor beta-3 TGFB3 Tbio Non-IDG -3.02749 1062.5 308
Zinc finger protein SNAI1 SNAI1 Tbio Transcription Factor -3.28636 1782.9 566