Development Level

Tbio 37 | 11,445
Tchem 12 | 1,598
Tclin 9 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
decreased body weight 2 | 161
embryonic lethality prior to t... 2 | 278
impaired pupillary reflex 2 | 26
impaired righting response 2 | 26
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo development 1 | 7
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
cleft palate 1 | 8
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased spleen weight 1 | 10
enlarged heart 1 | 210
fused cornea and lens 1 | 5
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 38 | 11,493
Cancer 31 | 2,499
ovarian cancer 29 | 8,520
psoriasis 29 | 6,694
lung cancer 27 | 4,740
osteosarcoma 25 | 7,950
Breast cancer 24 | 3,578
invasive ductal carcinoma 24 | 2,951
atypical teratoid / rhabdoid tumor 23 | 5,112
glioblastoma 22 | 5,792
lung carcinoma 20 | 2,843
malignant mesothelioma 20 | 3,232
interstitial cystitis 19 | 2,312
medulloblastoma, large-cell 19 | 6,241
Cleft Palate 18 | 271
ependymoma 18 | 4,679
Astrocytoma, Pilocytic 17 | 3,081
non-small cell lung cancer 16 | 2,890
Autosomal recessive predisposition 15 | 1,442
ductal carcinoma in situ 15 | 1,745
lung adenocarcinoma 15 | 2,716
adult high grade glioma 14 | 3,801
group 3 medulloblastoma 14 | 4,104
ulcerative colitis 14 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
oligodendroglioma 13 | 2,850
Prostatic Neoplasms 12 | 495
Short stature 12 | 531
astrocytic glioma 12 | 2,597
pancreatic cancer 12 | 2,398
breast carcinoma 11 | 1,638
cystic fibrosis 11 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
primitive neuroectodermal tumor 11 | 3,035
Breast Neoplasms 10 | 445
Cleft Lip 10 | 141
Heart disease 10 | 306
Kidney cancer 10 | 2,613
Lung Neoplasms 10 | 232
Mammary Neoplasms 10 | 425
adrenocortical carcinoma 10 | 1,428
pituitary cancer 10 | 1,972
Adenoma 9 | 167
Bipolar Disorder 9 | 666
Craniofacial Abnormalities 9 | 151
Depressive disorder 9 | 409
Endometriosis 9 | 540
Neoplasm Metastasis 9 | 168
Orbital separation excessive 9 | 244
diabetes mellitus 9 | 1,728
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 2,010
Anemia 8 | 365
Asthma 8 | 385
Carcinoma, Hepatocellular 8 | 228
Down syndrome 8 | 499
Dull intelligence 8 | 645
Epilepsy 8 | 792
Failure to gain weight 8 | 365
Hypertensive disease 8 | 292
Hypoplastic mandible condyle 8 | 275
Intellectual disability 8 | 1,016
Liver carcinoma 8 | 240
Low intelligence 8 | 645
Low set ears 8 | 181
Lung disease 8 | 142
Mandibular hypoplasia 8 | 275
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Micrognathism 8 | 275
Neoplasm Invasiveness 8 | 161
Pediatric failure to thrive 8 | 365
Poor school performance 8 | 645
Pulmonary Fibrosis 8 | 106
Rheumatoid arthritis 8 | 1,191
Schizophrenia 8 | 1,160
Seizures 8 | 596
Stomach Neoplasms 8 | 300
acute quadriplegic myopathy 8 | 1,158
cutaneous lupus erythematosus 8 | 1,057
group 4 medulloblastoma 8 | 1,855
Alzheimer's disease 7 | 658
Arthritis 7 | 290
Atopic dermatitis 7 | 952
Concave bridge of nose 7 | 195
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Diarrhea 7 | 253
Hypertension 7 | 396
Liver Cirrhosis 7 | 181
Mammary Neoplasms, Experimental 7 | 154
Mental Depression 7 | 333
Muscle hypotonia 7 | 571
Osteoporosis 7 | 363
colon cancer 7 | 1,478
medulloblastoma 7 | 720
non-small cell lung carcinoma 7 | 317
pediatric high grade glioma 7 | 1,064
sarcoidosis 7 | 370

Tissue

Digestive Tract 58 | 17,369
Endocrine System 58 | 18,159
Female tissues 58 | 17,400
Liver and Pancreas 57 | 16,750
Male tissues 57 | 17,142
Urinary Tract 57 | 16,678
Skin and soft tissues 56 | 17,230
Blood and immune system 55 | 16,909
Nervous System 55 | 16,725
Respiratory system 55 | 16,393
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 29 | 12,091
Transcription Factor 11 | 1,400
Kinase 7 | 634
Enzyme 6 | 4,145
GPCR 4 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GO Process

positive regulation of epithel... 59 | 59
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
von Hippel-Lindau-like protein VHLL Tdark Non-IDG -1.04303 10.1 37
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Zinc finger protein 304 ZNF304 Tbio Transcription Factor -0.83471 4.32 16
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318