Development Level

Tbio 23 | 11,445
Tchem 10 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal cornea morphology 2 | 31
corneal opacity 2 | 32
embryonic lethality prior to o... 2 | 239
fused cornea and lens 2 | 5
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
persistence of hyaloid vascula... 2 | 33
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
cataract 1 | 92
decreased circulating glycerol... 1 | 16
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
narrow eye opening 1 | 12
preweaning lethality, incomple... 1 | 499
prolonged RR interval 1 | 8
tremors 1 | 39

Disease

Carcinoma 25 | 11,493
osteosarcoma 21 | 7,950
ovarian cancer 21 | 8,520
Cancer 18 | 2,499
glioblastoma 18 | 5,792
pancreatic cancer 16 | 2,398
lung adenocarcinoma 15 | 2,716
lung cancer 14 | 4,740
medulloblastoma, large-cell 14 | 6,241
psoriasis 14 | 6,694
Breast cancer 13 | 3,578
atypical teratoid / rhabdoid tumor 12 | 5,112
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung carcinoma 11 | 2,843
invasive ductal carcinoma 10 | 2,951
malignant mesothelioma 10 | 3,232
non-small cell lung cancer 10 | 2,890
Astrocytoma, Pilocytic 9 | 3,081
ductal carcinoma in situ 9 | 1,745
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
oligodendroglioma 9 | 2,850
primary pancreatic ductal adenocarcinoma 9 | 1,109
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Bipolar Disorder 7 | 666
Hypertensive disease 7 | 292
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
interstitial cystitis 7 | 2,312
Breast Neoplasms 6 | 445
Hypertension 6 | 396
Kidney cancer 6 | 2,613
Mammary Neoplasms 6 | 425
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
Vascular disease 6 | 319
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
ulcerative colitis 6 | 1,819
Amyotrophic lateral sclerosis 5 | 451
Arthritis 5 | 290
Asthma 5 | 385
Cleft Palate 5 | 271
Depressive disorder 5 | 409
Down syndrome 5 | 499
Liver Cirrhosis, Experimental 5 | 769
Major Depressive Disorder 5 | 301
Mental Depression 5 | 333
Multiple myeloma 5 | 1,332
Rheumatoid arthritis 5 | 1,191
acute quadriplegic myopathy 5 | 1,158
diabetes mellitus 5 | 1,728
nephrosclerosis 5 | 333
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Alzheimer's disease 4 | 658
Attention deficit hyperactivity disorder 4 | 278
Cardiomegaly 4 | 116
Colonic Neoplasms 4 | 142
Coronary artery disease 4 | 268
Dental caries 4 | 164
Hyperalgesia 4 | 83
Inflammatory bowel disease 4 | 151
Kidney disease 4 | 430
Lung Neoplasms 4 | 232
Lung disease 4 | 142
Neurodegenerative disease 4 | 414
Orbital separation excessive 4 | 244
Parkinson's disease 4 | 392
Polycystic ovary syndrome 4 | 360
Prostatic Neoplasms 4 | 495
Short stature 4 | 531
Waldenstrons macroglobulinemia 4 | 765
chronic lymphosyte leukemia 4 | 204
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
progressive supranuclear palsy 4 | 676
Acquired scoliosis 3 | 281
Cerebrovascular disease 3 | 238
Curvature of spine 3 | 282
Duchenne muscular dystrophy 3 | 601
Heart disease 3 | 306
Migraine 3 | 83
active ulcerative colitis 3 | 764
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic carcinoma 3 | 562
pterygium 3 | 76

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Nervous System 36 | 16,725
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 7 | 4,145
Kinase 4 | 634
Transcription Factor 4 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242

GO Process

positive regulation of epithel... 36 | 36
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Protein phosphatase 1F PPM1F Tbio Enzyme -1.53852 37.0 236
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Calpain-7 CAPN7 Tbio Non-IDG -1.51078 32.0 65
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 ENPP2 Tchem Enzyme -2.62921 463.2 377
Golgi-associated plant pathogenesis-related protein 1 GLIPR2 Tbio Non-IDG -0.85891 11.0 109
Pro-cathepsin H CTSH Tchem Enzyme -2.36930 222.0 253
Profilin-1 PFN1 Tbio Non-IDG -2.31736 223.5 260
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657