Development Level

Tbio 4 | 11,445

IMPC Phenotype

abnormal brain morphology 1 | 13
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
athymia 1 | 2
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
hydroencephaly 1 | 14
hydrometra 1 | 53
increased monocyte cell number 1 | 63
small superior vagus ganglion 1 | 74

Disease

Carcinoma 4 | 11,493
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Hypoplastic mandible condyle 3 | 275
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Craniofacial Abnormalities 2 | 151
Cryptorchidism 2 | 296
Muscle hypotonia 2 | 571
Osteoporosis 2 | 363
Penile hypospadias 2 | 106
Short stature 2 | 531
Streak ovary 2 | 15
ependymoma 2 | 4,679
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pituitary cancer 2 | 1,972
46, XX Testicular Disorders of Sex Development 1 | 3
46,XY partial gonadal dysgenesis 1 | 9
46,Xx Sex Reversal 1 1 | 3
Abnormal sex determination 1 | 11
Abnormality of male internal genitalia 1 | 4
Abnormality of the labia 1 | 9
Abnormality of the scrotum 1 | 9
Aniridia 1 | 25
Aniridia 1 1 | 5
Aniridia cerebellar ataxia mental deficiency 1 | 2
Aniridia type 2 1 | 1
Anterior Segment Dysgenesis 5 1 | 4
Aplasia/Hypoplasia of the macula 1 | 8
Axenfeld-Rieger Syndrome, Type 1 1 | 3
Bifid scrotum 1 | 16
CATARACT, AUTOSOMAL DOMINANT 1 | 4
Campomelic dysplasia 1 | 7
Coloboma of Optic Nerve 1 | 2
Coloboma, Ocular, Autosomal Dominant 1 | 6
Congenital Hand Deformities 1 | 8
Congenital ectopic pupil 1 | 7
Congenital neurologic anomalies 1 | 20
Contiguous gene syndrome 1 | 2
Decreased fertility in females 1 | 20
Degenerative disc disease 1 | 35
Deletion 11p13 1 | 3
Disorder of the optic nerve 1 | 1
Displacement of the external urethral meatus 1 | 3
Dull foveal reflex 1 | 9
Elevated follicle stimulating hormone 1 | 15
Elevated luteinizing hormone 1 | 14
Explosive speech 1 | 9
FOVEAL HYPOPLASIA 1 1 | 1
Female external genitalia in males 1 | 13
Femoral bowing 1 | 20
Foveal hypoplasia (finding) 1 | 9
Foveal hypoplasia and presenile cataract syndrome 1 | 1
Foveal hypoplasia-presenile cataract syndrome 1 | 1
Gillespie syndrome 1 | 2
Hand Deformities, Congenital 1 | 8
Hypoplasia of vagina 1 | 14
Hypoplastic cervical vertebrae 1 | 3
Hypoplastic iliac wing 1 | 19
Hypoplastic inferior ilia 1 | 3
Hypoplastic scapulae 1 | 14
Keratitis, hereditary 1 | 1
Keratopathy 1 | 12
Morning glory syndrome 1 | 1
Nervous System Malformations 1 | 10
O'Donnell Pappas syndrome 1 | 1
Oligodactyly 1 | 6
Optic Nerve Diseases 1 | 1
Optic Nerve Hypoplasia, Bilateral 1 | 1
Optic nerve aplasia 1 | 3
Peters anomaly 1 | 16
Pierre Robin Syndrome 1 | 11
Presenile cataract 1 | 1
Rudimentary vagina 1 | 14
Scanning speech 1 | 9
Scleral staphyloma 1 | 1
Sex reversal 1 | 10
Short limb dwarfism recognizable at birth 1 | 9
Shortening of all phalanges of fingers 1 | 2
Skin dimple 1 | 2
Split hand-foot malformation 1 | 18
T cell deficiency 1 | 8
T-Lymphocytopenia 1 | 9
Testicular regression syndrome 1 | 9
Thymic dysplasia 1 | 3
Tibial bowing 1 | 19
Tracheobronchomalacia 1 | 2
True Hermaphroditism (disorder) 1 | 4
Upper airway obstruction 1 | 6
Urogenital sinus anomaly 1 | 15
Vaginal malformation 1 | 7
WAGR syndrome 1 | 10
XX males 1 | 3

Tissue

Blood and immune system 4 | 16,909
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Male tissues 4 | 17,142
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678
Liver and Pancreas 3 | 16,750
Nervous System 3 | 16,725
Cardiovascular System 2 | 15,192

Target Family

Transcription Factor 3 | 1,400
Non-IDG 1 | 12,091

GO Process

positive regulation of epithel... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Forkhead box protein N1 FOXN1 Tbio Transcription Factor -2.30206 196.4 204
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Protein Wnt-10b WNT10B Tbio Non-IDG -2.07635 120.7 149