Development Level

Tbio 41 | 11,445
Tchem 20 | 1,598
Tclin 9 | 613

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 3 | 278
decreased blood urea nitrogen ... 2 | 51
decreased circulating insulin ... 2 | 76
embryonic lethality prior to o... 2 | 239
hydrometra 2 | 53
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged uterus 1 | 11
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating glucose ... 1 | 24
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
short tibia 1 | 97
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 46 | 11,493
Cancer 44 | 2,499
osteosarcoma 37 | 7,950
ovarian cancer 37 | 8,520
glioblastoma 33 | 5,792
lung cancer 32 | 4,740
psoriasis 31 | 6,694
malignant mesothelioma 27 | 3,232
Breast cancer 26 | 3,578
lung adenocarcinoma 25 | 2,716
invasive ductal carcinoma 24 | 2,951
medulloblastoma, large-cell 23 | 6,241
atypical teratoid / rhabdoid tumor 22 | 5,112
non-small cell lung cancer 20 | 2,890
breast carcinoma 19 | 1,638
ependymoma 19 | 4,679
lung carcinoma 19 | 2,843
pancreatic cancer 19 | 2,398
ulcerative colitis 19 | 1,819
interstitial cystitis 18 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
cystic fibrosis 16 | 1,696
diabetes mellitus 16 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Kidney cancer 15 | 2,613
Schizophrenia 15 | 1,160
Vascular disease 15 | 319
Astrocytoma, Pilocytic 14 | 3,081
Hypertension 14 | 396
colon cancer 14 | 1,478
tuberculosis 14 | 2,010
Breast Neoplasms 13 | 445
Kidney disease 13 | 430
Mammary Neoplasms 13 | 425
ductal carcinoma in situ 13 | 1,745
group 3 medulloblastoma 13 | 4,104
oligodendroglioma 13 | 2,850
primitive neuroectodermal tumor 13 | 3,035
Alzheimer's disease 12 | 658
Heart disease 12 | 306
adult high grade glioma 12 | 3,801
Coronary artery disease 11 | 268
Prostatic Neoplasms 11 | 495
adrenocortical carcinoma 11 | 1,428
group 4 medulloblastoma 11 | 1,855
pituitary cancer 11 | 1,972
Asthma 10 | 385
Hypertensive disease 10 | 292
Obesity 10 | 678
aldosterone-producing adenoma 10 | 665
astrocytic glioma 10 | 2,597
astrocytoma 10 | 1,146
juvenile dermatomyositis 10 | 1,187
pediatric high grade glioma 10 | 1,064
Anemia 9 | 365
Atherosclerosis 9 | 291
Atopic dermatitis 9 | 952
Hemangioma 9 | 69
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
subependymal giant cell astrocytoma 9 | 2,287
Arthritis 8 | 290
Diabetic retinopathy 8 | 56
Endometriosis 8 | 540
Liver Cirrhosis 8 | 181
Liver Cirrhosis, Experimental 8 | 769
Major Depressive Disorder 8 | 301
Orbital separation excessive 8 | 244
Rheumatoid arthritis 8 | 1,191
Seizures 8 | 596
cutaneous lupus erythematosus 8 | 1,057
fibroadenoma 8 | 559
interstitial lung disease 8 | 298
primary pancreatic ductal adenocarcinoma 8 | 1,109
spina bifida 8 | 1,074
Autistic Disorder 7 | 364
Bipolar Disorder 7 | 666
Carcinoma, Hepatocellular 7 | 228
Colorectal Neoplasms 7 | 243
Depressive disorder 7 | 409
Downward slant of palpebral fissure 7 | 158
Duchenne muscular dystrophy 7 | 601
Epilepsy 7 | 792
Hyperglycemia 7 | 137
Liver carcinoma 7 | 240
Lung disease 7 | 142
Lymphedema 7 | 42
Multiple myeloma 7 | 1,332
Myocardial Ischemia 7 | 169
Pneumonia 7 | 174
Pulmonary Fibrosis 7 | 106
Allergic hypersensitivity disease 6 | 126
Cerebrovascular disease 6 | 238
Hypersensitivity reaction type II disease 6 | 253
Pick disease 6 | 1,894
acute quadriplegic myopathy 6 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
nasopharyngeal carcinoma 6 | 1,058
pancreatic carcinoma 6 | 562
periodontitis 6 | 293

Tissue

Endocrine System 70 | 18,159
Female tissues 70 | 17,400
Liver and Pancreas 70 | 16,750
Blood and immune system 69 | 16,909
Digestive Tract 69 | 17,369
Respiratory system 69 | 16,393
Skin and soft tissues 69 | 17,230
Urinary Tract 69 | 16,678
Cardiovascular System 68 | 15,192
Male tissues 68 | 17,142
Nervous System 68 | 16,725

Target Family

Non-IDG 43 | 12,091
Kinase 11 | 634
Transcription Factor 8 | 1,400
Enzyme 4 | 4,145
GPCR 2 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

positive regulation of endothe... 70 | 70
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 580 ZNF580 Tbio Transcription Factor -1.04597 11.4 74
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Rapamycin-insensitive companion of mTOR RICTOR Tbio Non-IDG -2.79454 597.0 440
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Semaphorin-5A SEMA5A Tbio Non-IDG -1.82162 69.8 238
Epidermal growth factor-like protein 7 EGFL7 Tbio Non-IDG -1.78690 72.8 217
Secretogranin-2 SCG2 Tbio Non-IDG -2.37107 283.4 175
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Tumor necrosis factor ligand superfamily member 12 TNFSF12 Tbio Non-IDG -2.49751 362.7 413
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390