Development Level

Tbio 6 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
pallor 1 | 34

Disease

Carcinoma 7 | 11,493
Cancer 6 | 2,499
osteosarcoma 6 | 7,950
atypical teratoid / rhabdoid tumor 5 | 5,112
breast carcinoma 5 | 1,638
lung adenocarcinoma 5 | 2,716
lung cancer 5 | 4,740
Osteoarthritis 4 | 184
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Breast cancer 3 | 3,578
Hemangioma, Cavernous 3 | 20
Hypertension 3 | 396
Immune system cancer 3 | 140
Liver Cirrhosis 3 | 181
Lymphoid leukemia 3 | 160
Mammary Neoplasms 3 | 425
Schizophrenia 3 | 1,160
Telangiectasis 3 | 36
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
ovarian cancer 3 | 8,520
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Abnormally small eyeball 2 | 97
Alzheimer's disease 2 | 658
Anemia 2 | 365
Arthritis, Juvenile 2 | 126
Arthritis, Rheumatoid 2 | 174
Brachydactyly 2 | 156
Carcinoma, Hepatocellular 2 | 228
Cataract 2 | 297
Chemical and Drug Induced Liver Injury 2 | 195
Cholecystitis 2 | 18
Cognitive delay 2 | 608
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Craniofacial Abnormalities 2 | 151
Decreased size of eyeball 2 | 97
Degenerative polyarthritis 2 | 115
Epistaxis 2 | 43
Global developmental delay 2 | 608
Heart disease 2 | 306
Hereditary hemorrhagic telangiectasia 2 | 13
Hypertension, Portal 2 | 22
Intermittent migraine headaches 2 | 68
Iron-Refractory Iron Deficiency Anemia 2 | 15
Juvenile arthritis 2 | 126
Lens Opacities 2 | 231
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Liver disease 2 | 237
Lung disease 2 | 142
Mental and motor retardation 2 | 608
Microphthalmos 2 | 100
Migraine Disorders 2 | 76
Multiple myeloma 2 | 1,332
Muscle hypotonia 2 | 571
Osteoporosis 2 | 363
Otosclerosis 2 | 15
Pulmonary hypertension 2 | 85
Rheumatoid arthritis 2 | 1,191
Skin cancer 2 | 469
Spontaneous haematoma 2 | 8
Spontaneous, recurrent epistaxis 2 | 3
Strabismus 2 | 270
Telangiectasia of the skin 2 | 39
Telangiectasia, Hereditary Hemorrhagic 2 | 3
Uterine Cervical Neoplasm 2 | 25
Uterine Cervical Neoplasms 2 | 26
Visceral angiomatosis 2 | 13
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
medulloblastoma 2 | 720
medulloblastoma, large-cell 2 | 6,241
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
pulmonary arterial hypertension 2 | 75

Tissue

Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 7 | 12,091
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

positive regulation of endothe... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Protein atonal homolog 8 ATOH8 Tbio Transcription Factor -0.96559 12.3 111
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Protein BTG1 BTG1 Tbio Non-IDG 0.13 1.00 154
ETS translocation variant 2 ETV2 Tbio Transcription Factor -1.64063 48.7 137
Arachidonate 12-lipoxygenase, 12S-type ALOX12 Tchem Enzyme -2.35458 223.8 137
Serine/threonine-protein kinase receptor R3 ACVRL1 Tchem Kinase -2.98370 969.8 432
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058